African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5232

Full Length Research Paper

Antimicrobial activity of seaweeds of Pernambuco, northeastern coast of Brazil

Renata Carla Corrêa Alves
  • Renata Carla Corrêa Alves
  • Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Pernambuco (UFPE), Av. Prof. Moraes Rego, 1235, Cidade Universitária, CEP 50670–901, Recife. PE, Brazil.
  • Google Scholar
Paula Fernanda Figueiredo das Mercês
  • Paula Fernanda Figueiredo das Mercês
  • Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Pernambuco (UFPE), Av. Prof. Moraes Rego, 1235, Cidade Universitária, CEP 50670–901, Recife. PE, Brazil.
  • Google Scholar
Isabel Renata Arruda de Souza
  • Isabel Renata Arruda de Souza
  • Centro de Tecnologias Estratégicas do Nordeste/Ministério da Ciência, Tecnologia e Inovação (CETENE/MCTI), Av. Prof. Moraes Rego, 01, Cidade Universitária, CEP 50740–540, Recife, Brazil.
  • Google Scholar
Clébia Maria Alves de Almeida
  • Clébia Maria Alves de Almeida
  • Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Pernambuco (UFPE), Av. Prof. Moraes Rego, 1235, Cidade Universitária, CEP 50670–901, Recife. PE, Brazil.
  • Google Scholar
Ana Paula Sant’Anna da Silva
  • Ana Paula Sant’Anna da Silva
  • Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Pernambuco (UFPE), Av. Prof. Moraes Rego, 1235, Cidade Universitária, CEP 50670–901, Recife. PE, Brazil.
  • Google Scholar
Vera Lúcia de Menezes Lima
  • Vera Lúcia de Menezes Lima
  • Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Pernambuco (UFPE), Av. Prof. Moraes Rego, 1235, Cidade Universitária, CEP 50670–901, Recife. PE, Brazil.
  • Google Scholar
Maria Tereza dos Santos Correia
  • Maria Tereza dos Santos Correia
  • Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Pernambuco (UFPE), Av. Prof. Moraes Rego, 1235, Cidade Universitária, CEP 50670–901, Recife. PE, Brazil.
  • Google Scholar
Márcia Vanusa da Silva
  • Márcia Vanusa da Silva
  • Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Pernambuco (UFPE), Av. Prof. Moraes Rego, 1235, Cidade Universitária, CEP 50670–901, Recife. PE, Brazil.
  • Google Scholar
Alexandre Gomes da Silva*
  • Alexandre Gomes da Silva*
  • Núcleo de Bioprospecção e Conservação da Caatinga, Instituto Nacional do Semiárido/Ministério da Ciência, Tecnologia e Inovação (INSA/MCTI), Av. Francisco Lopes de Almeida, s/n, Serrotão, CEP 58429-970 , Campina Grande, PB, Brazil.
  • Google Scholar


  •  Received: 08 June 2015
  •  Accepted: 10 August 2015
  •  Published: 14 March 2016

Abstract

The antibacterial efficacy of various solvent extracts of marine algae Caulerpa racemosa, Ulva lactuca (Chlorophyta), Jania adhaerens (Rhodophyta), Padina gymnospora and Sargassum polyceratium (Phaeophyta) against some selected gram-positive and gram-negative human pathogenic bacteria was screened. Crude extracts were prepared from the selected marine algae using different solvents namely, hexane, chloroform, ethyl acetate and methanol and were tested for their antibacterial activity against human pathogenic bacteria using disc diffusion method. Minimum inhibitory concentration (MIC) was also determined for selected solvent extracts for all the bacterial species. A suitable positive control was also maintained. Among the five marine algae screened C. racemosa and U. lactuca were found to be more active. It was observed that the ethyl acetate extracts of all the five marine algae showed higher inhibitory activity for the selected bacterial species than other solvent extracts. The results revealed that the crude ethyl acetate extracts seem to be a good source material in identifying the effective pure antibacterial compound(s) in all the five marine algae and particularly, C. racemosa and U. lactuca. The present study showed that the ethyl acetate extracts of marine algae such as C. racemosa, J. adhaerens, P. gymnospora, S. polyceratium and Ulva lactuca exhibited good antimicrobial activity. But the ethyl acetate extracts of C. racemosa and U. lactuca possessed highest antibacterial activity than others and so it could be useful in seeking active principles against human pathogenic bacteria.

Key words: Seaweeds, antimicrobial activity, marine macroalgae, human bacterial pathogens.