African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5232

Full Length Research Paper

The bactericidal and fungicidal effects of salicid on pathogenic organisms involved in hospital infections

S. M. E. Rahman, Joong Hyun Park and Deog-Hwan Oh*
Department of Food Science and Biotechnology, Institute of Bioscience and Biotechnology, Kangwon National University, Chuncheon, Gangwon 200-701, Republic of Korea.
Email: [email protected]

  •  Accepted: 15 July 2011
  •  Published: 16 September 2011

Abstract

The study was designed to investigate bactericidal and fungicidal actions of salicid (pH: 6.7, ORP: 760 mV, residual chlorine of 2 to 5 ppm) on hospital infections. Four of the most common opportunistic pathogens (Klebsiella pneumoniaeStaphylococcus aureus,Rhizopus oryzae, and Aspergillus fumigatus) were used for this study. Cultures were inoculated in 9 mL of salicid and incubated for 0.5, 1, 3, 5, 7 and 10 min at room temperature (23 ± 2°C). A dipping method was followed for this study. Untreated pathogens were treated as control. Compared to the untreated control, a reduction of 1.10 to 6.08 log10 CFU/mL for aforementioned pathogens were recorded as the result of treatment with 2 and 5 ppm salicid, respectively. The highest bactericidal effect was found with S. aureus for 5 ppm salicid with 0.5 min immerse time. Salicid treatment with 0.5 min dipping and 5 ppm residual chlorine also reduced K. pneumoniaeR. oryzae, and A. fumigatus by 5.00, 3.50 and 2.63 log10 CFU/mL, respectively. Our findings showed that in each pathogen, efficacy of salicid decreased significantly (p < 0.05) with increased dipping time, from 0.5 to 10 min and there was significant difference (p < 0.05) observed between 2 and 5 ppm salicid treatment in reducing pathogens. The results indicate that salicid may be a useful disinfectant for hospital infections, but its clinical application has still to be evaluated.  

 

Key words: Salicid, Bactericidal and fungicidal effect, Hospital infections.