Studies on yeasts exposed non-steroidal anti-inflammatory drugs (NSAIDs) such as acetylsalicylic acid (aspirin) as potential anti-mitochondrial antifungals. In this study, various NSAIDs were tested for antifungal activity on the human yeast pathogens Candida albicans and Cryptococcus neoformans. Our results suggest a dual action for these drugs, that is, antifungal as well as anti-inflammatory. These results could be useful in the treatment of fungal infections.
Key words: Acetylsalicylic acid, antifungal, anti-inflammatory drugs, anti-mitochondrial,Candida albicans, Cryptococcus neoformans, Eremothecium ashbyi.
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