Abstract

This research was conducted to evaluate the antidiabetic effect of camel milk in alloxan-induced-diabetic dogs. Diabetes was induced by intravenous injection of alloxan monohydrate (65 mg/kg bodyweight). The effects of camel milk on diabetic dogs were investigated by observing changes in the glycometabolic index (fasting blood glucose,intravenous glucose tolerance test (IGTT)) test, the lipometabolic index (triglyceride, cholesterol), total proteins and in the degree of injury of β-cells in the pancreatic islets. A significant decrease in fasting plasma glucose, cholesterol and total proteins in blood sample and an improvement on the animal clinical state (increase of body weight, normal activity) was observed. Camel milk also induces renewal of pancreatic β-cells. A comparison was made between the effect of camel milk and cow milk. Treatment with cow milk does not have any benefit effect on alloxan-induced diabetic dogs.

Key words: Alloxan, diabetes, dogs, antidiabetic effect, camel milk, β-cells.