January 2013
Variables determining the virologic response to adefovir treatment in patients with chronic HBV infection previously treated with lamivudine
The objective of this study was the investigation of the variables that determine the development of virological response to adefovir treatment. In this retrospective case-control study, files of patients with chronic HBV infection which previously used adefovir throughout different periods were examined for gender, age, height, weight, Knodell and fibrosis scores in liver biopsies, serum ALT and HBV DNA...
January 2013
Effects of ascorbic acid, citric acid, lactic acid, NaCl, potassium sorbate and Thymus vulgaris extract on Staphylococcus aureus and Escherichia coli
Staphylococcus aureus and some strains of Escherichia coli are frequently implicated in foodborne diseases. This study examined the effects of some compounds (ascorbic acid, citric acid, lactic acid, sodium chloride, potassium sorbate and Thymus vulgaris extract) on growth of S. aureus and E. coli. Lactic acid (0.03% or 0.1%) alone nearly completely inhibited growth of S....
January 2013
Isolation and characterization of naphthalene-degrading strains, Pseudomonas sp. CZ2 and CZ5
Bacterial strains CZ2 and CZ5, isolated from polycyclic aromatic hydrocarbons contaminated sludge in Wuhan, China, can utilize naphthalene as a sole source of carbon. They were both identified as Pseudomonas based on Gram staining and 16S rRNA gene sequence analysis. Pseudomonas sp. CZ2 and CZ5 can remove 61.8 and 64.3% of naphthalene with an initial concentration of 1...
January 2013
Development of a simplified and efficient method for genetic transformation of Gymnoascus reesii
The identification of complex genetic determinants that control the ability of a fungus to produce bioactive compounds enhances molecular breeding strategies. Through a series of optimizations, we developed a system for the genetic transformation of Gymnoascus reesii that can produce nematicidal activity against the root-knot nematode Meloidogyne incoginta. The optimal conditions for protoplast...
January 2013
Aetiology and frequency of cervico-vaginal infections among Mexican women
There are major concerns worldwide regarding sexually transmitted infections (STI), bacterial vaginosis (BV), and candidiasis as a major cause of morbidity as they result in significant health and economic consequences, particularly in developing countries. This study was intended to obtain information about the prevalence of these pathologies in women considered to be at low risk using both traditional...
January 2013
Unexpected hazard due to Fumonisins contaminating herbal teas used traditionally by Saudi people
Fumonisins are mycotoxins synthesized by various species of the genus Fusarium and are hazardous for human and animal health. The purpose of this study was to investigate fumonisin B1 (FB1) in herbal tea consumed especially by Saudi population. FB1 was detected using high performance liquid chromatography (HPLC) with fluorescence detection. Forty-seven commercially available samples for infusions...
January 2013
Solubilization of insoluble potassium and phosphate by Paenibacillus kribensis CX-7: A soil microorganism with biological control potential
From wheat field soil samples of Chang’an, Shanxi, seven multifunctional strains with the ability of solubilizing phosphate and potassium were isolated for its utilization as a biological fertilizer, and the most efficient strain named CX-7 was chosen for further study. CX-7 was identified as Paenibacillus kribbensis after a series of physiological and biochemical experiments, morphological observation...
January 2013
Engineering and evaluation of a mouse/human chimeric antibody against Shiga toxin 2
Hemolytic-uremic syndrome (HUS), mainly caused by Shiga toxin (Stx) producingEscherichia coli (STEC) such as E. coli O157:H7 and STEC/EAggEC, is a serious complication predominantly leading to renal failure and even death. We have previously reported that a monoclonal antibody effectively neutralizes Stx2 in vitro and in vivo toxicity models. As a therapeutic agent against HUS, the...
January 2013
Prevalence and comparison for detection methods of Candida species in vaginal specimens from pregnant and non pregnant Saudi women
Pregnancy represents a risk factor in the occurrence of vulvovaginal candidiasis. To investigate the prevalence rate of vaginal carriage of Candida species in Saudi pregnant and non-pregnant women, high vaginal swab (HVS) specimens (707) were examined by direct microscopy (10% KOH and Giemsa staining) and parallel cultured on Sabouraud Dextrose Agar (SDA) as well as on “CHROM agar...
January 2013
Cryptococcal meningitis with concurrent pulmonary cryptococcosis: Retrospective clinical analysis of 12 cases
The clinical and imaging characteristics of cryptococcal meningitis (CM) with concurrent pulmonary cryptococcosis (PC) were presented in the present study. Retrospective clinical data analysis of 20 histopathologically confirmed cases of CM with concurrent PC. The patients included eight males and four females, with four 62-year olds and an average age of 33.3 years ± 23.8 years. The...
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