African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2288

Review

A review of ethnopharmacology of the commonly used antimalarial herbal agents for traditional medicine practice in Ethiopia

Asmare Amuamuta
  • Asmare Amuamuta
  • Center of Excellence in Pharmacology and Molecular Biology of Malaria and Cholangiocarcinoma, Chulabhorn International College of Medicine, Thammasat University, Klonglung, Pathum Thani, Thailand.
  • Google Scholar
Kesara Na-Bangchang*
  • Kesara Na-Bangchang*
  • Center of Excellence in Pharmacology and Molecular Biology of Malaria and Cholangiocarcinoma, Chulabhorn International College of Medicine, Thammasat University, Klonglung, Pathum Thani, Thailand.
  • Google Scholar


  •  Received: 18 November 2014
  •  Accepted: 15 June 2015
  •  Published: 09 July 2015

Abstract

Malaria is one of the parasitic infections that cause enormous public health, economic, and emotional burden in many tropical and subtropical countries of the world. Resistance of the vector mosquitoes to the current insecticides as well as the emergence of multidrug resistance by malaria parasite to widely used antimalarial drugs has made malaria control and treatment much more difficult. New alternative antimalarial drugs and approaches for mosquito control are urgently required. Ethiopia, as most of the African continent countries, is rich in a wide range of tropical habitats, remarkable biodiversity, and the uses of traditional medicines for treatment of various illnesses. The article thus focuses on review of ethnopharmacological activities (medicinal properties), phytochemistry, and safety (toxicity) of some of the commonly used antimalarial herbal agents in Ethiopia and around which could have significant potential for antimalarial drug discovery and development.

Key words: Medicinal plants, malaria, efficacy and safety, Ethiopia.