Full Length Research Paper
Abstract
A series of several diazenyl schiff base molecules were designed and synthesized through azo coupling of diazotised primary amines with the novel synthesized schiff base ligand (E)-N-((2-chloroquinolin-3-yl)methylene)-4-phenylthiazol-2-amine. All the synthesized molecules have been characterized by different spectral techniques for their structural confirmation. The results of in vitro antioxidant activity of the molecules by 2,2-diphenyl-1- picryl hydrazyl (DPPH) assay method revealed that the molecules (NZ)-N-(((4-chlorophenyl) diazenyl) (2-chloroquinolin-3-yl) methylene) -4- phenylthiazol -2-amine (5A) and 4-(((Z)-(2-chloroquinolin-3-yl)(4-phenylthiazol-2-ylimino)methyl)diazenyl)phenol (5E) have shown potential free radical scavenging activity.
Key words: Schiff base, diazenyl, spectral, antioxidant.
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