African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2285

Full Length Research Paper

Fixed and volatile constituents of Croton heliotropiifolius Kunth from Bahia-Brazil

Douglas Dourado Oliveira
  • Douglas Dourado Oliveira
  • Laboratory of Research in Materia Medica, Faculty of Pharmacy, Federal University of Bahia, 40170290, Salvador-BA, Brazil.
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Cinara Vasconcelos da Silva
  • Cinara Vasconcelos da Silva
  • Laboratory of Research in Materia Medica, Faculty of Pharmacy, Federal University of Bahia, 40170290, Salvador-BA, Brazil.
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Maria Lenise Silva Guedes
  • Maria Lenise Silva Guedes
  • Alexandre Leal Costa Herbarium, Institute of Biology, Federal University of Bahia, 40170290, Salvador-BA, Brazil.
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Eudes da Silva Velozo
  • Eudes da Silva Velozo
  • Laboratory of Research in Materia Medica, Faculty of Pharmacy, Federal University of Bahia, 40170290, Salvador-BA, Brazil.
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  •  Received: 14 December 2015
  •  Accepted: 28 April 2016
  •  Published: 15 July 2016

Abstract

Essential oils from Croton heliotropiifolius Kunth roots and stems, popularly known in Bahia (Brazil) as velame or cassutinga, were obtained by hydro distillation. Fixed oil from the roots of this species was obtained by maceration in hexane. The oils were analyzed by nuclear magnetic resonance (NMR) and gas chromatography coupled with mass spectrometry (GCMS). 46 compounds were identified in the stems and 35 substances were found in the roots. The principal components oils were camphor, β-pinene, and α-pinene in the stems, and camphor, borneol, valencene, and viridiflorol in the roots. The fixed oil contained C8 to C18 fatty acids. It is the first study that reports the presence of fixed oil from the roots of this genus.

 

Key words: Croton heliotropiifolius, Euphorbiaceae, essential oils composition, fixed oil composition, velame.

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