African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2285

Full Length Research Paper

Supercritical fluid and pharmaceutical applications. Part I: Process classification

Valquíria Miwa Hanai Yoshida
  • Valquíria Miwa Hanai Yoshida
  • LaBNUS – Biomaterials and Nanotechnology Laboratory, University of Sorocaba, Sorocaba/SP, Brazil.
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Victor Manuel Cardoso Figueiredo Balcão
  • Victor Manuel Cardoso Figueiredo Balcão
  • LaBNUS – Biomaterials and Nanotechnology Laboratory, University of Sorocaba, Sorocaba/SP, Brazil.
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Marta Maria Duarte Carvalho Vila
  • Marta Maria Duarte Carvalho Vila
  • LaBNUS – Biomaterials and Nanotechnology Laboratory, University of Sorocaba, Sorocaba/SP, Brazil.
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José Martins Oliveira Júnior
  • José Martins Oliveira Júnior
  • LaFINAU – Laboratory of Applied Nuclear Physics, University of Sorocaba, Sorocaba/SP, Brazil.
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Norberto Aranha
  • Norberto Aranha
  • LaFINAU – Laboratory of Applied Nuclear Physics, University of Sorocaba, Sorocaba/SP, Brazil.
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Maria Palmira Daflon Gremião
  • Maria Palmira Daflon Gremião
  • Pharmaceutical Sciences School of São Paulo State University – UNESP, Araraquara/SP, Brazil.
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Marco Vinícius Chaud
  • Marco Vinícius Chaud
  • LaBNUS – Biomaterials and Nanotechnology Laboratory, University of Sorocaba, Sorocaba/SP, Brazil.
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  •  Received: 30 December 2014
  •  Accepted: 31 December 2015
  •  Published: 08 March 2016

Abstract

The supercritical fluid technology has been target of many pharmaceuticals investigations in particles production for almost 35 years. This is due to the great advantages it offers over others technologies currently used for the same purpose. A brief history is presented, as well the classification of supercritical technology based on the role that the supercritical fluid (carbon dioxide) performs in the process.

Key words: Supercritical fluid technology, supercritical carbon dioxide, pharmaceuticals.

Copyright © 2024 Author(s) retain the copyright of this article.

This article is published under the terms of the Creative Commons Attribution License 4.0

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