African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2285

Full Length Research Paper

Therapeutic and preventive effects of Commiphora gileadensis against diethylnitrosamine-induced hepatic injury in albino rats

Doa’a Anwar, I.
  • Doa’a Anwar, I.
  • Pharmacology Department, College of Pharmacy, University of Science and Technology, Sana’a, Yemen.
  • Google Scholar
Amani, S.
  • Amani, S.
  • Histopathology Department Hospital Lab, University of Science and Technology, Sana’a, Yemen
  • Google Scholar
Alzoreqy, A.
  • Alzoreqy, A.
  • Histopathology Department Hospital Lab, University of Science and Technology, Sana’a, Yemen
  • Google Scholar
Al-Dbhani, A.
  • Al-Dbhani, A.
  • Histopathology Department Hospital Lab, University of Science and Technology, Sana’a, Yemen
  • Google Scholar
Al-Fteih, L.
  • Al-Fteih, L.
  • Histopathology Department Hospital Lab, University of Science and Technology, Sana’a, Yemen
  • Google Scholar
Abu-Al-fatah, T.
  • Abu-Al-fatah, T.
  • Histopathology Department Hospital Lab, University of Science and Technology, Sana’a, Yemen
  • Google Scholar
QojaNazer, H.
  • QojaNazer, H.
  • Histopathology Department Hospital Lab, University of Science and Technology, Sana’a, Yemen
  • Google Scholar
Alnoor, E.
  • Alnoor, E.
  • College of Pharmacy, University of Science and Technology, Sana’a, Yemen.
  • Google Scholar


  •  Received: 29 May 2015
  •  Accepted: 07 October 2015
  •  Published: 29 April 2016

References

Abicht K, El-Samalouti V, Junge W, Kroll M, Luthe H, Treskes M, Klein G (2001). Multicenter evaluation of new GGT and ALP reagents with new reference standardization and determination of 37°C reference intervals. Clin. Chem. Lab. Med. 39(Suppl):S346

 

Al Howiriny T, Mohammed A, Al-Yahya, Mansour S, Al-Said, Kama l, El-Tahir EH, S Rafatullah (2004). Studies on the pharmacological activities of an ethanol extract of Balessan (Commiphora opoblsamum). Pak. J. Biol. Sci. 7(11):1933-1936.

 
 

Ala-Kokko L, Pihlajaniemi T, Myers JC, Kivirikko KI, Savolainen ER (1987). Gene expression of type I, III and IV collagens in hepatic fibrosis induced by dimethylnitrosamine in the rat. Biochem. J. 244:75-79.

 
 

Al-Amoudi NS (2009). Hypocholesterolemic effect of some plants and their blend as studied on albino rats. Int. J. Food Saf. Nutr. Public Health 2(2):176.

 
 

Al-Howiriny TA, Al-Sohaibani MO, El-Tahir KH, Rafatullah S (2003). Preliminary evaluation of the anti-inflammatory and anti-hepatotoxic activities of `Parsley' Petroselinum crispum in rats. J. Nat. Remed. 3(1):54-62.

 
 

Al-Rejaie S (2009). Progression of diethylnitrosamine-induced hepatic carcinogenesis in carnitine- depleted rats. World J. Gastroenterol. 15(11):1373-1380.

 
 

Altkofer W, Braune S, Ellendt K, Kettl-Grömminger M, Steiner G (2005). "Migration of nitrosamines from rubber products--are balloons and condoms harmful to the human health?" Mol. Nutr. Food Res. 49(3):235-8.
Crossref

 
 

Archer MC (1989). Mechanisms of action of N-nitrosocompounds. Cancer Surv. 8:241-250.

 
 

Bachoric P (2000). Measurement of Low-Density-Lipoprotein. In: Handbook of Lipoprotein Testing (eds. Rifai, Warnick and Dominiczak), 2nd edition, AACC press. pp. 245-263.

 
 

George J, Chandrakasan G (1996). Molecular characteristics of dimethylnitrosamine induced fibrotic liver collagen. Biochem. Biophys. Acta 1292:215-222.

 
 

George J. Rao K, Stern R, Chandrakasan (2001). Diethylnitrosamine-induced liver injury in rats: the early deposition of collagen. Toxicology 156:129-138.

 
 

Gupta C, Vikram A, Tripathi DN, Ramarao P, Jena GB (2010). Antioxidant and antimutagenic effect of quercetin against DEN induced hepatotoxicity in rat. Phytother. Res. 24(1):119-128.

 
 

Jaykaran PB, Kantharia N, Yadav P, Panwar A (2008). Acute toxicity study of an aqueous extract of Ficus racemosa Linn. bark in albino mice. Internet J. Toxicol. 6(1).

 
 

Jones SHL (1924). ed., The Geography of Strabo, Cambridge, MA: Harvard University press; London; William Heinemann, Ltd.

 
 

Jose JK, Kuttan R, Bhattacharaya RK (1998). Effect of Emblica officinalis extract on hepatocarcinogenesis and carcinogen metabolism. J. Clin. Biochem. Nutr. 25:31-39.

 
 

Kalaiselvan A, Gokulakrishnan K, Anand T, Akhilesh U, Velavan S (2013). Preventive Effect of Shorea Robusta Bark Extract against Diethylnitrosamine-Induced Hepatocellular Carcinoma in Rats. Int. Res. J. Med. Sci. 1(1):2-9.

 
 

Kikuzaki H, Sato A, Mayahara Y, Natakani N (2000). Galloylhlucosides from berries of Pimento dioica. J. Natural Prod. 63(6):749.

 
 

Knudson PE, Weinstock RS (2001). Carbohydrates. In: Henry JB, ed. Clinical Diagnosis and Management by Laboratory Methods. 20th ed. Philadelphia: WB Saunders. pp. 211-223

 
 

Magee PN, Barnes JM (1967). Carcinogenic nitroso compounds. Adv. Cancer Res. 10:163-246.

 
 

Mohammed F, Ahmed S, Sultan, Al-shimaa MA (2014). Chemopreventive and therapeutic effect of capsaicin against diethylnitrosamine induced liver injury and hepatocellular carcinoma in rats. Int. J. Biol. Pharm. Res. 5(8):630-642.

 
 

Pisani T, Gebski CP, Leary ET, Warnick GR, Ollington JF (1995). Accurate direct determination of low-density lipoprotein cholesterol using an immunoseparation reagent and enzymatic cholesterol assay. Arch. Pathol. Lab. Med. 119:1127-35)

 
 

Pliny G (1989). Naturalis Historia (Jones WHS, translator). LCL, London.

 
 

Schumann G, Bonora R, Ceriotti F, Férard G, Ferrero CA, Franck PF (2002). IFCC Primary Reference Procedures for the Measurement of Catalytic Activity Concentrations of Enzymes at 37°C – Part 4. Reference Procedure for the Measurement of Catalytic Activity Concentrations of Alanine Aminotransferase. Clin. Chem. Lab. Med. 40(7):718-724.

 
 

Sivaramkrishnan V, Shilpa PNM, Kumar VRP Devaraj SN (2008). Attenuation of N-nitrosodiethylamine- induced hepatocellular carcinogenesis by a novel flavonol-Morin. Chem. Biol. Interact 171:79-88.

 
 

Sonntag O, Scholer A (2001). Drug interferences in clinical chemistry: recommendation of drugs and their concentrations to be used in drug interference studies. Ann Clin. Biochem. 38:376-385.

 
 

Stein EA, Myers GL (1995). National Cholesterol Education Program recommendations for triglyceride measurement: executive summary. The National Cholesterol Education Program Working Group on Lipoprotein Measurement. Clin. Chem. 41:1421-1426.

 
 

Swann PF, Magee PN (1971). Nitrosamine induced Carcinogenesis. Biochem. J. 125:841-847.

 
 

Vogel G (1977). Natural substances with effects on the liver. In: Wagner B, Wolff R (Eds). "New Natural Products and Plant Drugs with Pharmacological, Biological or Therapeutic Activity." Springer-Verlag, Heidelberg. pp. 249-256.

 
 

Zohary M (1973). Geobotanical Foundations of the Middle East, volumes 1, 2. Gustav Fischer Verlag, Stuttgart, Germany. ASIN B0006CB7Z4.

 
 

Zohary M (1982). Plants of the Bible: A Complete Handbook to All the Plants with 200 Full-Color Plates Taken in the Natural Habitat. London, UK: Cambridge University Press.