African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2286

Full Length Research Paper

Pharmacokinetics of gallic acid following oral administration of Triphala formulation in rats

Piracha Jumpa-ngern
  • Piracha Jumpa-ngern
  • Chulabhorn International College of Medicine, Thammasat University, Pathumthani, Thailand.
  • Google Scholar
Tullayakorn Plengsuriyakarn
  • Tullayakorn Plengsuriyakarn
  • Chulabhorn International College of Medicine, Thammasat University, Pathumthani, Thailand. 2Center of Excellence in Pharmacology and Molecular Biology of Malaria and Cholangiocarcinoma, Thammasat University, Pathumthani, Thailand.
  • Google Scholar
Kesara Na-Bangchang
  • Kesara Na-Bangchang
  • 1Chulabhorn International College of Medicine, Thammasat University, Pathumthani, Thailand. 2Center of Excellence in Pharmacology and Molecular Biology of Malaria and Cholangiocarcinoma, Thammasat University, Pathumthani, Thailand. 3Drug Discovery and Development Center, Office of Advanced Science and Technology, Thammasat University, Pathumthani, Thailand.
  • Google Scholar


  •  Received: 06 June 2021
  •  Accepted: 28 July 2021
  •  Published: 31 August 2021

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Ma F, Gong X, Zhou X, Zhao Y, Li M (2015). An UHPLC-MS/MS method for simultaneous quantification of gallic acid and protocatechuic acid in rat plasma after oral administration of Polygonum capitatum extract and its application to pharmacokinetics. Journal of Ethnopharmacology 62:377-383.
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Mukherjee PK, Rai S, Bhattacharya S, Wahile A, Saha BP (2008). Marker analysis of polyherbal formulation, Triphala-a well known Indian traditional. Indian Journal of Traditional Knowledge 7(3):379-383.

 
 

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Peterson CT, Denniston K, Chopra D (2017). Therapeutic Uses of Triphala in Ayurvedic Medicine. Journal of Alternative and Complementary Medicine 23(8):607-614.
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Phetkate P, Kummalue T, Kietinun S (2012). Significant increase in cytotoxic T lymphocytes and natural killer cells by triphala: a clinical phase I study. Evidence-Based Complementary and Alternative Medicine Article ID 239856.
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Phetkate P, Plengsuriyakarn T, Na-Bangchang K, Rinthong P, Kietinun S, Sriyakul S (2019). Acute and subacute oral toxicity evaluation of the water extract of triphala formulation in rats. International Journal of Biology, Pharmacology and Allied Science 8(4):779-792.

 
 

Phetkate P, Kummalue P, Rinthong PO, Kietinun S, Sriyakul K (2020). Study of the safety of oral Triphala aqueous extract on healthy volunteers. Journal of International Medicine 18(1):35-40.
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Takauji Y, Miki K, Mita J, Hossain M, Yamauchi M, Kioi M, Ayusawa D, Fujii M (2016). Triphala, a formulation of traditional Ayurvedic medicine, shows protective effect against X-radiation in HeLa cells. Journal of Bioscience 41(4):569-575.
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Wongnoppavich A, Kanjana J, Seewaboon S (2009). Triphala: The Thai traditional herbal formulation for cancer treatment. Songklanakarin Journal of Science and Technology 31(2):139-149.