African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2286

Full Length Research Paper

Hypolipidemic and antithrombotic evaluation of Myrtus communis L. in cholesterol-fed rabbits

Rafeeq Alam Khan*
  • Rafeeq Alam Khan*
  • College of Medicine-Jeddah, Department of Basic Medical Sciences, King Saud bin Abdulaziz University for Health Sciences, Kingdom of Saudi Arabia., Department of Pharmacology, Faculty of Pharmacy, University of Karachi, Karachi-75270, Pakistan
  • Google Scholar
Zeeshan Feroz
  • Zeeshan Feroz
  • College of Science and Health Professions, Department of Basic Sciences, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia.
  • Google Scholar
Maria Jamil
  • Maria Jamil
  • Department of Pharmacology, Faculty of Pharmacy, University of Karachi, Karachi-75270, Pakistan
  • Google Scholar
Mansoor Ahmed
  • Mansoor Ahmed
  • Department of Pharmaceutical Chemistry, University of Karachi, Karachi-75270, Pakistan
  • Google Scholar


  •  Published: 28 February 2014

References

Aghasadeghi K, Zarei-Nezhad M, Keshavarzi A, Mehrabani D (2008). The prevalence of coronary risk factors in Iranian lor migrating tribe. Arch. Iran. Med. 11(3): 322-325.
Pubmed
 
Alcaraz MJ, Jimenez MJ (1989). Anti-inflammatory compound from Sideritis javalambrensis n-hexane extract. J. Nat. Prod. 52:1088-1091.
Crossref
 
Aleksic V, Knezevic P (2013). Antimicrobial and antioxidative activity of extracts and essential oils of Myrtus communis L. Microbiol. Res. http://dx.doi.org/10.1016/j.micres.2013.10.003.
Crossref
 
Allen JK, Young DR, Blumenthal RS, Moy TF, Yanek LR, Wilder L, Becker LC, Becker DM (1996). Prevalence of hypercholesterolemia among siblings of persons with premature coronary heart disease. Arch. Intern. Med. 156(15): 1654–1660.
Crossref
 
Asif HM, Akram M, Uddin S, Hasan ZU, Sami A, Iqbal A, Tauseef U, Bari A (2011). Myrtus communis Linn. (Pharmacological activity). J. Med. Plant Res. 5(26): 6257-6259.
 
Atzei AD (2003). Le piante nella tradizione popolare della Sardegna. Sassari, Italy: Carlo Delfino Editore. pp. 319–323.
 
Azaizeh H, Fulder S, Khalil K, Said O (2003). Ethnomedicinal knowledge of local Arab practitioners in the Middle East Region. Fitoterapia 74:98-108.
Crossref
 
Banerjee SK, Maulik SK (2002). Effect of garlic on cardiovascular disorders: a review. Nutr. J. 1:4.
Crossref
 
Barazzoni R, Zanetti M, Davanzo G, Kiwanuka E, Carraro P, Tiengo A, Tessari P (2000). Increased fibrinogen production in type 2 diabetic patients without detectable vascular complications: correlation with plasmaglucagon concentrations. J. Clin. Endocrinol. Metab. 85(9):3121-3125.
Crossref
 
Cakir A (2004). Essential oil and fatty acid composition of the fruits of Hippophae rhamnoides L. and Myrtus communis L. from Turkey. Biochem. Systemat. Ecol. 32:809–816.
Crossref
 
Chan K, Yin M, Chao W (2007). Effect of di-allyltrisulfide-richgarlicoil on blood coagulation and plasma activity of anticoagulation factors in rats. Food Chem. Toxicol. 45:502-507.
Crossref
 
Diaz AM, Abeger A (1986). Study of the polyphenolic compounds present in alcoholic extracts of Myrtus communis L. seeds. An Real Acad. Farm. 52:541–546.
 
Di Cera E (2008). Thrombin Review. Mol. Aspects Med. 29:203-254.
Crossref
 
Eitzman DT, Westrick RJ, Xu Z, Tyson J, Ginsburg D (2000). Hyperlipidemia promotes thrombosis after injury to atherosclerotic vessels in apolipoproteinE–deficient mice. Arterioscl. Throm. Vasc. 20(7):1831-1834.
Crossref
 
Friedwald WT, Levy RI, Fredrickson DS (1972). Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of ultra centrifuge. Clin. Chem.18: 499-502.
 
Gailani D, Renne T (2007). Intrinsic pathway of coagulation and arterial thrombosis. Arteriosclerosis Thrombosis Vasc. Biol., 27: 2507-2513.
Crossref
 
Gortzi O, Lalas S, Chinou I, Tsaknis J (2008). Reevaluation of bioactivity and antioxidant activity of Myrtus communis extract before and after encapsulation in liposomes. Eur. Food Res. Technol. 226:583-590.
Crossref
 
James JS, Halit S, Geoffrey HT, Travis HM, Patrice S, Izabela L, Joseph MM, Peter FW, James EM, D'Agostino RB (2000). Association of Fibrinogen with Cardiovascular Risk Factors and Cardiovascular Disease in the Framingham Offspring Population. Circulation 102:1634-1638.
Crossref
 
Jung M, Park M, Lee HC, Kang YH, Kang ES, Kim SK (2006). Antidiabetic agents from medicinal plants. Curr. Med. Chem. 13:1203-1218.
Crossref
 
Kabiri N, Asgary S, Setorki M (2011). Lipid lowering by hydroalcoholic extracts of Amaranthus caudatus L. induces regression of rabbit's atherosclerotic lesions. Lipids Health. Dis. 10: 89.
Crossref
 
Lane DA, Philippou H, Huntington JA (2005). Directing Thrombin. Blood 6:2605-2612.
Crossref
 
Mahmood ZA, Sualeh M, Mahmood SB, Karim MA (2010). Herbal treatment for cardiovascular disease the evidence based therapy. Pak. J. Pharm. Sci. 23(1):119-124.
Pubmed
 
Marcel L, Steven MO. (2006). Coagulation abnormalities in critically ill patients. Critical Care10:222 DOI: 10.1186/cc4975.
Crossref
 
Martin T, Villaescusa L, De Sotto M, Lucia A, Diaz AM (1990). Determination of anthocyanin pigments in Myrtus communis berries. Fitoterapia 61:85.
 
National Research Council (1996). Guide for the Care and Use of Laboratory Animals. Washington, DC: National Academy Press. pp. 1-7.
 
Paul L, Kailash P (2003). Suppression of Oxidative Stress as a Mechanism of Reduction of Hypercholesterolemic Atherosclerosis by Cyclooxygenase Inhibitors. Int. J. Angiol. 12:13–23.
Crossref
 
Romani A, Pinelli P, Mulinacci N, Vincieri FF, Tattini M (1999). Identification and quantification of polyphenols in leaves of Myrtus communis. Chromatographia 49:17–20.
Crossref
 
Rosa A, Melis MP, Deiana M, Atzeri A, Appendino G, Corona G, Incani A, Loru D, Dessì MA (2008). Protective effect of the oligomeric acylphloroglucinols from Myrtus communis on cholesterol and human low density lipoprotein oxidation. Chem. Phys. Lipids 155(1):16-23.
Crossref
 
Ross R (1999). Atherosclerosis- An Inflammatory Disease. N. Engl. J. Med. 340(2):115-126.
Crossref
 
Satrani B, Farah A, Talbi M. (2006). Fractional distillation effect on the chemical composition and antimicrobial activity of Moroccan Myrtle. Acta Bot. Gallica 153:235–242.
Crossref
 
Serce S, Ercisli S, Sengul M, Gunduz K, Orhan E (2010). Antioxidant activities and fatty acid composition of wild grown myrtle (Myrtus communis L.) fruits. Pharmacogn. Mag. 6(21): 9-12.
Crossref
 
Shikhiev AS, Abbasov RM, Mamedova ZA (1978). Composition of Myrtus communis essential oil. Khimiya Prirodnykh Soedinenii 4:529–530.
 
Srivastava SK, Rai V, Srivastava M, Rawat AKS, Mehrotra S (2006). Estimation of heavy metals in different Berberis Species and its market samples. Environ. Monit. Assess.116:315-320.
Crossref
 
Trinder P (1969). Enzymatic colorimetric determination of triglycerides by GPO-PAP Method. Ann. Clin. Biochem. 6:24-27.
 
Verma AK, Kumar M, Bussmann RW (2007). Medicinal plants in an urban environment: the medicinal flora of Banares Hindu University, Varanasi, Uttar Pradesh. J. Ethnobiol. Ethnomed. 3:35.
Crossref
 
Zhao Y, Zhang J, ZhangJ, Wu J (2011). Diabetes mellitus is associated with shortened activated partial thromboplastin time and increased fibrinogen values. PLoS One 6(1):e16470.
Crossref