April 2014

Evaluation of the effects of long-term of pharmacotherapeutic follow-up intervention on clinical and humanistic outcomes in diabetes mellitus patients

This study aimed to evaluate the long-term effects of pharmacotherapeutic follow-up on clinical parameters and the quality of life of a group of elderly patients. A longitudinal pilot study was carried out to examine 14 elderly patients with diabetes mellitus 12 months after they completed the pharmacotherapeutic follow-up in a popular Pharmacy in Aracaju-SE, Brazil. Glycosylated hemoglobin, blood pressure, blood...

Author(s): Blície Jennifer Balisa-Rocha, Patrícia Melo Aguiar, Karine Santos Cerqueira, Micaele de Barros Novaes, Thaciana dos Santos Alcântara and Divaldo Pereira de Lyra Júnior

April 2014

Pakistani physicians’ knowledge and attitude towards reporting adverse drug reactions

The present study was designed to investigate the knowledge and attitude of Pakistani physicians towards adverse drug reaction (ADR) reporting. In this study, five hundred and fifty survey forms were distributed among the physicians belonging to different private and public sector clinics and hospitals of Karachi through email or direct correspondence. Two hundred and twenty five physicians provided consent to show...

Author(s): Wajiha Iffat, Sadia Shakeel, Najia Rahim, Fakhsheena Anjum, Shagufta Nesar and Sana Ghayas

April 2014

In vitro cytotoxic and genotoxic evaluation to ascertain toxicological potential of ketoprofen

Analgesic and anti-inflammatory properties of ketoprofen are well documented but little is known about its cytotoxic activity and the potential to damage the DNA. The present study was designed to evaluate the cytotoxic and genotoxic potential of ketoprofen. MTT dye (3-(4, 5-Dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide) was used to assess cytotoxicity in which confluent monolayer of vero cells were incubated...

Author(s): Dawood Ahmad Hamdani, Aqeel Javeed, Muhammad Ashraf, Jawad Nazir, Aamir Ghafoor, Imran Altaf and Muhammad Shahbaz yousaf

April 2014

Chemical composition and antimicrobial activity of essential oil from Brazilian plants Acanthospermum australe, Calea fruticosa and Mikania glauca

The essential oils of leaves of Acanthospermum australe, Calea fruticosa and Mikania glauca (Asteraceae) from southeastern Brazil were obtained by hydrodistillation and analyzed by gas chromatography-mass spectrometry (GC-MS). Oxygenated sesquiterpenes were predominant in C. fruticosa (47.8%) whereas sesquiterpenes hydrocarbons constituents predominated in A. australe (85.1%) and M. glauca (63.3%) oils. Caryophyllene...

Author(s): Cintia Cristina de Carvalho, Izabel Cristina Casanova Turatti, Norberto Peporine Lopes, Marcos José Salvador and Andréa Mendes do Nascimento