July 2014

Simultaneous spectrophotometric determination of phenacetin and paracetamol in human plasma for the quantitative assessment of liver function reserve

A simple, economical and reliable spectrophotometric method was developed for the simultaneous determination of phenacetin and paracetamol in human plasma. We purified the plasma samples by solid phase extraction procedure. The analytes reacted with chromogenic sodium 1,2-naphthoquinone-4-sulfonate and cetyltrimethyl ammonium bromide, and the products conformed to Beer’s law over the range 2 to 24 μg/ml for...

Author(s): Peng Yang, Lei Shi, Lin-Na Liu, Xin-You Liu, Xiang-Rui Wang, Ping He and Yan Zhang

July 2014

Resveratrol alleviates oxidative stress and inflammation in the hippocampus of rats subjected to global cerebral ischemia/reperfusion: Comparison with vitamin E

Resveratrol is a dietary polyphenol present in nuts and dried fruits. It is a potent antioxidant and anti-inflammatory agent; these properties led researchers to investigate its protective effects in several animal models of neurological disease, particularly those in which inflammation and oxidative stress may play a role in their pathogenesis. Thus it seemed interesting to study the possible neuro-protective effect of...

Author(s): Zainab K. Mahdi, Rania M. Abdelsalam and Azza M. Agha