Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3835

Full Length Research Paper

Terpens from aerial parts of Euphorbia splendida

Seyed Abdolmajid Ayatollahi1,4, Asie Shojaii1,4*, Farzad Kobarfard1,2, Mitra Nori3, Mohammad Fathi5 and Mohammad Iqbal Choudhari6
1Department of pharmacognosy, School of Pharmacy, Shahid Beheshti University, M.C., Tehran, Iran. 2Department of medicinal chemistry, School of Pharmacy, Shahid Beheshti University, M.C., Tehran, Iran. 3Department of biology, School of Science, Arak University, Arak, Iran. 4Phytochemistry Research Center, Shahid Beheshti University, M.C., Tehran, Iran. 5International center for chemical and biological sciences, H. E. J. Research Instituted of Chemistry, Karachi University, Karachi, Pakistan. 6Department of Anesthesiology, School of Medicine, Shahid Beheshti University, M.C., Tehran, Iran.
Email: [email protected]

  •  Accepted: 09 July 2009
  •  Published: 30 September 2009

Abstract

Euphorbia splendida Mobayen (Euphorbiaceae) is one of the Euphorbia species that has not been studied so far. The aerial parts of this plant was collected from Arak, Iran and extracted with methanol (by maceration). The dried extract was subjected to exhaustive separation by column chromatography and preparative TLC. Two terpens, a lupane-type triterpenoid and a diterpene with a tricylic lathyrane skeletone, were isolated and purified and identified as 3-28-dihydroxylup-20(29)-ene (betulin) and decipinone respectively for the first time from this plant. The structures of the isolated compounds were elucidated on the basis of spectroscopic methods including 1 and 2 D-NMR, IR, UV and MS.

 

Key words: Chromatography, diterpene, triterpen, betulin, decipinone.

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