September 2009
Traditional plants to modern medicine and methods for ex situ conservation of native medicinal plants
September 2009
The pharmacology and clinical properties of Kalopanax pictus
Kalopanax pictus is known as Castor-Aralia or Prickly Castor-oil tree. K. pictusextracts have been used for dietary health supplements and are an important area in drug development with numerous pharmacological functions in East Asia; however, their pharmacological functions have not been introduced in Western countries. This paper briefly reviews the most relevant experimental data on the pharmacological...
September 2009
Antimicrobial activity of ethanolic and aqueous extracts of Sida acuta on microorganisms from skin infections
The antimicrobial effect of the ethanolic and aqueous extracts of Sida acuta was investigated. Phytochemical analysis revealed the presence of saponins; tannins, cardiac glycosides, alkaloids and anthraquinones. The test isolates from human skin infections were Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa, Escherichia coli, Scopulariopsis candida, Aspergillus...
September 2009
Hypoglycaemic effect of Thymelaea hirsuta in normal and streptozotocin-induced diabetic rats
The present study has investigated the effect of oral administration of the aqueous extract of Thymelaea hirsuta (T.hirsuta) on blood glucose levels in normal, glucose-hyperglycemic and streptozotocin (STZ)-induced diabetic rats.In normal rats, single oral administration of T. hirsuta lowered blood glucose levels significantly. It omitted significantly reduced the fasting glucose level in rats...
September 2009
Determination of infochemicals and the phytochemical screening of the foliage and stem-bark of Senna siamea (lam.) in Yola, Adamawa State
Alkaloids, anthraquinonnes, cardiac glycosides, flavonoids, phlobatannin, polyphenols, saponins, steroids, tannins and terpenoids were ten groups of infochemicals studied in the foliage and stem-bark of Senna siamea (Lam.), a plantation species grown in Yola. The experimental design was the Randomized Complete Block Design (RCBD) with four replications. Results obtained from the experiments indicated that all the ten...
September 2009
Analgesic, anti-inflammatory and antiulcer properties of the extract of Uapaca guineensis (Euphorbiaceae)
Uapaca guineensis is an euphorbiaceae used traditionally for the management of pain and inflammation. The present study was aimed to investigate the analgesic, anti-inflammatory and anti-ulcer properties of the methanol extract of stilt root barks of U. guineensis in rats and mice. The analgesic properties of U. guineensis were investigated using the acetic acid writhing, hot plate as well as...
September 2009
Effects of Ruellia praetermissa extract on ovulation, implantation, and the uterine endometrium of female rats
The effects of extracts of Ruellia praetermissa (Acanthaceae) on ovulation, implantation, uterine weight and foetal development were studied in adult rats. Female rats weighing 180 to 220 g were divided into three experimental groups. Group 1 was administered 200 mg/kg body weight of the extract at 10, 14 and 18 h respectively on proestrous rats. Vaginal smears were taken daily to monitor the oestrous cycle...
September 2009
Insulin secreting and a-glucosidase inhibitory activity of Coscinium fenestratum and postprandial hyperglycemia in normal and diabetic rats
This work focused on the effect of Coscinium fenestratum ethanolic extract on plasma glucose concentrations in normal and streptozotocin (STZ)-induced diabetic rats, the stimulatory effect on insulin secretion from perfused rat pancreas and the inhibitory effects on rat intestinal α-glucosidase enzymes, maltase and sucrase. In oral glucose, maltose and sucrose loading tests, the extract (250 -...
September 2009
Promotion of seed germination, subsequent seedling growth and in vitro propagation of korarima (Aframomum corrorima (Braun) P.C.M. Jansen)
The germination of korarima (Aframomum corrorima (Braun) P.C.M. Jansen) seeds faces certain problems. The study was carried out to explore the effects of different seed treatments on germination and seedling growth attributes of korarima. Seeds were subjected to seven pre-sowing treatments viz., control (no pretreatment) (T0), soaking in tap water for 24 h (T1), soaking in 50% sulfuric acid...
September 2009
Terpens from aerial parts of Euphorbia splendida
Euphorbia splendida Mobayen (Euphorbiaceae) is one of the Euphorbia species that has not been studied so far. The aerial parts of this plant was collected from Arak, Iran and extracted with methanol (by maceration). The dried extract was subjected to exhaustive separation by column chromatography and preparative TLC. Two terpens, a lupane-type triterpenoid and a diterpene with a tricylic lathyrane...
September 2009
In vitro evaluation of antimicrobial activity of combinations of nystatin and Euphorbia hirta leaf extract against Candida albicans by the checkerboard method
The in vitro combined effects of Nystatin and methanol extract of leaves ofEuphorbia hirta against clinical isolates of Candida albicans were investigated using the Checkerboard technique. The organism was susceptible to the extract with MIC of 25 mg/ml, while Nystatin had MIC of 0.165 mg/ml against C. albicans. Upon combination, some ratios showed synergistic while others indicated...
September 2009
Gas chromatography-mass spectrometric studies of stems essential oil of Pinus roxburghaii and their antibacterial and antifungal activities
Essential oil of Pinus roxburghaii stems was analyzed by GC MS and their antibacterial activity was studied. Seventeen components out of fifty-two were identified in the oil. Major component in essential oil was α- pinene (41.9%) followed by 3-carene (16.3%), caryophyllene (12.3%), p-cymene (1.9%), Terpinenol (1.8%), Limonene (1.7%), Borneol acetate(1.1%), Caryophyllene oxide (1.0%),camphene...
September 2009
Mosquito larvicidal and cytotoxic activities of 3 Annona species and isolation of active principles
Cytotoxicity and larvicidal properties of the leaf extracts of 3 Annonaceous plants, Annona muricata L., A. senegalensis Pers and A. squamosa L. were tested against brine shrimp larva and the late 3rd instar of Culex quinquefascintus Say. The larval mortality was observed 24 h post-exposure. Based on the probit analysis, the LC50 value for crude extracts of A....
September 2009
A growth regulator for the propagation of Lippia multiflora Moldenke, a herbal for the management of mild hypertension in Ghana
A growth regulator containing 0.43% of Naphylacetric acid was applied to the propagation stocks (apical meristem, root and stem cuttings) of Lippia multifloraMoldenke using different soil media. The result shows that the applied growth regulator enhanced the germination of the root cuttings more than the other propagation stocks. The germination and sustainability of the root cuttings on transplanting onto the...
September 2009
Inhibition of endotoxin-Induced pro-inflammatory markers by water extracts of Onopordum cynarocephalum and Achillea damascena
Water extracts of Onopordum cynarocephalum (Oc) and Achillea damascena(Ad), traditionally used in Lebanon to treat various medical conditions including inflammatory diseases, were evaluated for anti-inflammatory activities employing an in vitro model of endotoxin (ET)-induced inflammation in mammary epithelial SCp2 cells and an in vivo model of ET-induced paw edema in male rats....
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