Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3835

Full Length Research Paper

Antimicrobial and antioxidant activities of essential oil and methanol extract of Matricaria chamomilla L. from Djibouti

Fatouma M. Abdoul-Latif1, 2, Nabil Mohamed4, Prosper Edou3, Adwa A. Ali4, Samatar O.Djama4, Louis-Clément Obame5, 6*, Ismael H. N. Bassolé5 and Mamoudou H. Dicko2
1Laboratoire de Biologie, Université de Djibouti, BP 1904 Djibouti, République de Djibouti. 2Laboratoire BAEBIB, Université de Ouagadougou. 03 BP: 7021 Ouagadougou 03. Burkina Faso. 3Laboratoire Pluridisciplinaire des Sciences (LAPLUS), Ecole Normale Supérieure, BP 7131 Libreville, Gabon. 4Centre d’Etudes et de Recherches en Biotechnologie BP 486 Djibouti, République de Djibouti. 5Centre de Recherche en Sciences Biologiques, Alimentaires et Nutritionnelles, Laboratoire de Microbiologie etde Biotechnologie, Université de Ouagadougou 03 BP 7131 Ouagadougou Burkina Faso. 6Laboratoire de Substances Naturelles (LASUNA), USTM, Département de Chimie, BP 769, Franceville Gabon.
Email: [email protected]

  •  Accepted: 04 February 2011
  •  Published: 04 May 2011

Abstract

The essential oil and methanol of Matricaria Chamomilla L. were subjected to screening for their possible antioxidant activity by two complementary test systems, namely 2,2-Diphenykpicrylhydrazyl (DPPH) free radical scavenging and β-carotene-linoleic acid assays. BHT was used as positive control in both test systems. In the DPPH test system, the IC50 value of essential oil and methanol extract were respectively 4.18 and 1.83 µg/ml. In the β-carotene-linoleic acid system, oxidation was effectively inhibited by M. Chamomilla, the RAA value of essential oil and methanol extract were respectively 12.69 and 11.37%. When compared to BHT, the oil and methanol extract were nearly the same value. The essential oil and methanol extract were tested against bacterial and fungal strains using a broth microdilution method. The results suggest that M. Chamomilla, oil and methanol extract have significant antimicrobial activity.

 

Key words: Matricaria chamomilla L., essential oil, methanol extract, antioxidant activity, antimicrobial activity.