November 2013
Comparative effects of Sorghum bicolor leaf base extract on tissues isolated from some body systems of experimental animals
The knowledge of the effect(s) of substances to be used as medicines on different body systems is very vital in drug development vis-`a-vis drug safety. The effects of aqueous methanolic extract of Sorghum bicolor leaf base were tested on cardiovascular system-related in vitro models (such as isolated rat atria and rat portal vein), gastrointestinal system-related in vitro models (such as isolated rabbit jejunum, guinea...
November 2013
Evaluation of acute, subacute and subchronic oral toxicity of Rhaphidophora decursiva (Roxb.) Schott extract in male Sprague Dawley rats
Rhaphidophora decursiva (Roxb.) Schott has been used in some Chinese community to treat colon cancer. This study aims to evaluate the toxic effects of the plant extract after a single dose toxicity study (14-day acute toxicity study), as well as 28-day sub-acute and 90-day subchronic toxicity study in male Sprague Dawley rats. Seventy two rats were divided into 3 groups for the acute, sub-acute and sub-chronic toxicity...
November 2013
Determination of catechin as main bioactive component of gambir (Uncaria gambir Roxb) by FT-NIR Spectroscopy
Catechin, an abundant component within gambir, is the main determinant of gambir quality. The general method to determine catechin is time consuming, costly and produces chemical residual. The objective of this study was to develop NIR calibration model which could be used to predict catechin content of gambir efficiently. Calibration model was established using partial least square (PLS) algorithm by investigating 3...
November 2013
Contribution of fenugreek (Trigonella foenum graecum L.) seeds towards the nutritional characterization
In the present investigation biochemical contents in fenugreek seeds were estimated. Results revealed minimum polyphenol content in genotype NDM-278. Genotype HM-267 recorded the maximum phytic acid while RM-185 recorded the maximum saponin content. The maximum carbohydrate was observed in the genotypes NDM-12 and ACC-012 however; the maximum protein content in genotype NDM-33. Genotype HM-258-1 estimated the maximum...
November 2013
Effects of different ecological conditions and extraction techniques on the quality of volatile oils from flaxleaf fleabane (Erigeron bonariensis L.)
The objective of this study was mainly to compare the chemical composition of essential oils from the whole parts of Erigeron bonariensis obtained by traditional hydrodistillation technique and by supercritical fluid extraction recognized as an alternative efficient method. A comparison of the effects of different ecological conditions on the chemical composition of essential oil samples collected in different...
November 2013
A review on Decalepis hamiltonii Wight & Arn.
Decalepis hamiltonii is a climbing shrub with aromatic tuberous roots distributed in Southern parts of Peninsular India. Its tuberous roots are widely used as a health drink and are well known for its medicinal properties. D. hamiltonii is one of the important plants in Ayurvedic system of medicine in India and are used in curing various diseases like stomach disorders, gastric ulcers and to stimulate appetite. This...
November 2013
Preliminary phytochemical screening and antimicrobial activities of various fractions of Mallotus philippensis Muell.
The phytochemical studies and biochemical screening of various fractions, that is, hexane, chloroform, ethyl acetate, butanol and aqueous (F1 to F5) obtained from the medicinal plant Mallotus phillipensis were studied. The presence of alkaloids, flavonoids, glycosides, phenols, quinines, saponins, tannins and terpenoids were confirmed by performing chemical tests using standard protocols. The infrared (IR) spectroscopic...
November 2013
In vitro and in vivo antioxidant activity of Ixora coccinea
Ixora coccinea Linn. commonly known as Rangon, belongs to the family Rubiaceae. Antioxidant activity of root of I. coccinea extract was evaluated in a series of in vitro assay involving free radicals. IC50 values were determined. Extracts of I. coccinea exhibited scavenging effect in concentration dependent manner in all in vitro method. IC50 of ethyl acetate extract was 48.43, 75.811 and 60.60 µg/ml for...
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