Abstract

Nature always stands as a golden mark to exemplify the outstanding phenomena of symbiosis. Acne vulgaris is an extremely common disorder affecting many adolescents and adults throughout their lifetimes. The pathogenesis of acne is multifactorial and is thought to involve excess sebum, follicular hyperkeratinization, bacterial colonization, and inflammation. Pomegranate, Punica granatum Linn. (Punicaceae) is an ancient, mystical, unique fruit used in several systems of medicine for a variety of ailments. The synergistic action of the pomegranate constituents appears to be superior to that of single constituents. The current research was focused on evaluation of anti-acne activity ofPunica extract followed by its biological screening. The fingerprinting and spectroscopic analysis of the extract was determined. The attempt was made to investigate the extract ofP. granatum for the said activity with the goal of elucidating the active potential compounds.

Key words: Punica granatum, broth dilution, cup plate method, high performance thin layer chromatography.