Scientific Research and Essays

  • Abbreviation: Sci. Res. Essays
  • Language: English
  • ISSN: 1992-2248
  • DOI: 10.5897/SRE
  • Start Year: 2006
  • Published Articles: 2745

Full Length Research Paper

Analysis of the antimicrobial action of copaiba oil and endodontic substances against anaerobic bacteria

Amaro de Mendonça Cavalcante
  • Amaro de Mendonça Cavalcante
  • Faculty of Dentistry, Federal University of Alagoas, (FOUFAL-UFAL), Maceió, AL, Brazil.
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Joanna Rodrigues da Silva
  • Joanna Rodrigues da Silva
  • Faculty of Dentistry, Federal University of Alagoas, (FOUFAL-UFAL), Maceió, AL, Brazil.
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Lisiane Cristina Lopes Oliveira
  • Lisiane Cristina Lopes Oliveira
  • Faculty of Dentistry, Federal University of Alagoas, (FOUFAL-UFAL), Maceió, AL, Brazil.
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Marcos Aurelio Bonfim da Silva
  • Marcos Aurelio Bonfim da Silva
  • Faculty of Dentistry, Federal University of Alagoas, (FOUFAL-UFAL), Maceió, AL, Brazil.
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Karlos Antônio Lisboa Ribeiro Junior
  • Karlos Antônio Lisboa Ribeiro Junior
  • Center of Agricultural Sciences, Federal University of Alagoas, (CECA-UFAL) Rio Largo, AL, Brazil.
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Antônio Euzébio Goulart de Santana
  • Antônio Euzébio Goulart de Santana
  • Center of Agricultural Sciences, Federal University of Alagoas, (CECA-UFAL) Rio Largo, AL, Brazil.
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  •  Received: 30 July 2020
  •  Accepted: 02 December 2020
  •  Published: 31 January 2021

Abstract

Endodontic infections are polymicrobial and predominantly caused by anaerobic bacteria and some facultative bacteria. The list of microorganisms involved in endodontic infections keeps expanding and has the potential to become increasingly more accurate during the next few years. Copaiba oil is an important Amazonian herbal medicine commercialized worldwide.  In this study, we evaluated the antimicrobial activity and minimum inhibitory concentration (MIC) of copaiba oil and substances used in the treatment of endodontic infections against anaerobic microorganisms such as Prevotella melaninogenica; Prevotella intermedia; and Clostridium acetobutylicum. The MIC was determined by thioglycollate broth dilution. The data were statistically analyzed by Tukey's parametric and non-parametric methods of Cochran and Kruskal-Wallis test with a confidence level of 99%. The analysis of the antimicrobial activity showed that the samples of Copaíba oil, Sodium Hypochlorite, Otosporin, Tricresol formalin, Chlorhexidine and PMCC showed high antimicrobial activity (p <0.01). However, different copaiba samples presented different activities. The results reveal Copaíba l sample was the most effective against anaerobic bacteria.

Key words: Essential oil, endodontic therapy, anaerobic microorganisms.