Journal of
Toxicology and Environmental Health Sciences

  • Abbreviation: J. Toxicol. Environ. Health Sci.
  • Language: English
  • ISSN: 2006-9820
  • DOI: 10.5897/JTEHS
  • Start Year: 2009
  • Published Articles: 217

JTEHS Articles

The protective role of 3-aminothiazolo[3-2a]benzimadzole-2-carbonitrile against lung and colon injury induced by nitrosomorpholine in adult male albino rat

July 2013

Nitrites and morpholine are ubiquitous environmental contaminants found in drinking water and food. NMOR can be formed endogenously from nitrite and morpholine. Increased levels of reactive oxygen species/ reactive nitrite species (ROS/RNS) are involved in the mechanism of NMOR toxicity. Certain antimicrobial, antifungal and antioxidant potential were observed in heterocyclic benzimidazole derivatives and dimethyl...

Author(s): Hossam El-Din M. Omar, Heba M. Saad El-Din, Elham A. Abd-Allah and Abdelwareth A. O. Sarhan

Modulatory effects of kolaviron (Garcinia kola extract) on spermogram and reproductive system of adult male wistar rats in lead acetate induced toxiocity

July 2013

This study was designed to determine the effects of the concomitant administration of kolaviron (Garcinia kola extract) with lead on male fertility by evaluating some spermogram and histopathology of the testis. 20 adult male Wistar rats were randomly divided into 4 groups of 5 rats each. The rats in group O (negative control) were given normal saline, while rats in group A were given 6 mg/kg body weight of lead...

Author(s): Jegede Ayoola Isaac, Ajadi Mary Bolanle and Akinloye Oluyemi,

Metals bioavailability in the leachates from dumpsites in Zaria Metropolis, Nigeria

July 2013

Landfill leachates pose a significant threat to both surface water and groundwater especially the wells adjacent to landfills. The study investigated the bioavailability of zinc (Zn), copper (Cu), lead (Pb), cadmium (Cd) and mercury (Hg) from leachates of ten huge dumpsites across the metropolitan city of Zaria. The trends in the mean concentrations of the metals (mg/L) among the fractions were; Zn: total > mobile...

Author(s): Sani Uba, Adamu Uzairu, Muhammad Sani Sallau, Hamza Abba and Okunola Oluwole Joshua

The challenge of future landfill: A case study of Malaysia

June 2013

Landfilling is the most frequent waste disposal method worldwide. It is recognised as being an important option both now and in the near future, especially in low- and middle-income countries, since it is the easiest and the cheapest technology available. Owing to financial constraints, landfills usually lack of environmental abatement measures, such as leachate collection systems and lining materials. As a result, a...

Author(s): Sharifah Norkhadijah Syed Ismail, and Latifah Abd. Manaf

Effects of gas flaring on rainwater quality in Bayelsa State, Eastern Niger-Delta region, Nigeria

June 2013

The aim of the paper was to study the spatial effects of gas flaring on rainwater quality in Bayelsa State, Eastern Niger-Delta, Nigeria. The physicochemical variables were isolated from the analysis of rainwater samples from eight locations in the State, while mean monthly rainfall data for 2011 of the selected areas was collected from the Port Harcourt International Airport which has a distance of 15 km to the...

Author(s): E. E. Ezenwaji, A. C. Okoye and V. I. Otti

Acute toxicity test of two pesticides diazinon and deltamethrin on spirlin (Alburnoides bipunctatus) larvae and fingerling

June 2013

The present research was performed to determine and compare acute toxicity of diazinon and deltamethrin to spirlin larvae and fingerling. Diazinon and deltamethrin are common useful agricultural pesticides. LC50 of 24, 48, 72 and 96 h was attained by probit analysis software SPSS Version 16. Fish samples (21 fish in each test group) were exposed to different...

Author(s): Mohammad Forouhar Vajargah, Sayede Amene Hossaini and Aliakbar Hedayati

Prevention of acute ammonia toxicity in bluga (Huso huso), using natural zeolite

May 2013

The research was accomplished in order to study the efficiency of natural zeolite to prevent acute toxicity of ammonia on Huso huso. The study was performed using Water static method for 96 h. Fish with average weight 46 ± 5 g and total length 22 ± 4 cm were exposed to four different concentrations (15, 30, 50, 75 mg L-1) of ammonia salt. A group of fish was considered as control. Under stable...

Author(s): Mohammad Farhangi, Hosna Gholipour-Kanani, and Faramarz Rostami-Charati

Pesticides-induced oxidative damage: Possible in vitro protection by antioxidants

May 2013

This study was designed to investigate the effect of selenium (Se) and a combination of vitamin E (VE) vitamin C (VC) on pesticides induced biochemical alterations in rat erythrocytes and hepatocytes in vitro. Vitamin E and C and selenium are potential antioxidants, known to be able to protect cells against oxidative damage. In vitro changes in antioxidant systems and protective role of selenium and a...

Author(s): Ahmed K. Salama, Khaled A. Osman and Omran A. Omran

Comparison of World Trade Center dust with zinc acetate and lead oxide combinations to determine damage to human lung cells

April 2013

The exposures of the World Trade Center (WTC) dust of the September 11, 2001 tragedy are linked to increased respiratory problems and emergence of World Trade Center Cough. Zinc (Zn) and Lead (Pb) are among the many heavy metals found in WTC dust. Synergistic effects among several chemicals might be contributing to respiratory illness. The individual toxicity, and combination treatments of Pb and Zn at a particular...

Author(s): Niharika Pattnaik and Ann Marie DiLorenzo

A spectrophotometric method for quantification of sulphite ions in environmental samples

April 2013

This study described an alternative method developed for the quantification of sulphite ions in environmental samples. The method was based on results of an investigation of the reaction of excess pentacyanidonitrosylferrate(II) popularly known as nitroprusside (NP) and the sulphite anion. NP-SO32- reaction product by use of zinc-ethylenediamine complex cation(s) was stabilized. The NP-SO32-  reaction...

Author(s): Peter Musagala, Henry Ssekaalo, Jolocam Mbabazi and Muhammad Ntale

Opposite effects of Ca2+ on toxicity by CdCl2 on white blood cells (WBC), protein level and LD50 of rabbits Oryctolagus cuniculus

March 2013

Heavy metals and their derivatives are a special class of toxic substances. Many metals are useful for industrial, agricultural and medical applications. Indeed, they can go back through the food chain and thus achievable to human being. Our aim is to study an example of heavy metals cadmium (CdCl2) at two concentrations 30 and 60 ppm on biological model Oryctolagus cuniculus that is often used in...

Author(s): Rachid Rouabhi, Bouchiha Hanene, Bouchama Khaled, Berrebbah Houria and Djebar MohamedReda

Inclusion of incorrect information on snakebite first aid in school and university teaching materials in Nepal

March 2013

In previous studies in Nepal, snakebite victims were found to either not have Pressure Immobilization Bandaging (PIB) or Local Compression Pad Immobilization (LCPI) performed for first aid, or had it performed incorrectly. The goal of this study was to evaluate training texts regarding first aid measures for snakebite and the rates of performance of both methods currently recommended, as well as ineffective or harmful...

Author(s): Deb P. Pandey, and Bishnu P. Khanal,

Correlation between glutathione S-transferase Mu 1 (GSTM1) and glutathione S-transferase pi gene (GSTP1) polymorphisms and markers of inflammatory stress in pregnant females

March 2013

The Mother and Child Environmental Cohort (MACE) study piloted in South Africa in 2010 to 2011, collected genetic, biochemical and clinical data from pregnant females residing in south and north Durban. We evaluated birth outcomes and the influence of GSTM1pos→GSTM1null and theGSTP1 (Ile105Val; AA→AG/GG) polymorphisms on the extent of DNA damage and with biomarkers [glutathione (GSH) and...

Author(s): Poovendhree Reddy, Rajen N. Naidoo, Anil Chuturgoon, Kareshma Asharam, Dhaneshree Naidoo, Alisa Phulukdaree and Shivona Gounden

Water and sanitation situation in Nima and Teshie, Greater Accra Region of Ghana

February 2013

This study examined the water and sanitation (WATSAN) situation in Nima and Teshie, Greater Accra Region of Ghana. A number of research instruments and methods of primary and secondary data collection were employed. These were focus group discussions (FGD), field observation, and interviews. Data collected were edited, coded, and analyzed with the aid of Statistical Package for Social Scientists (SPSS) to...

Author(s): Doris A. Fiasorgbor

Non-cancer risk assessment from exposure to mercury (Hg), cadmium (Cd), arsenic (As), copper (Cu) and lead (Pb) in boreholes and surface water in Tinga, in the Bole-Bamboi District, Ghana

February 2013

The study assessed non-cancer human health risk from exposure to mecury (Hg), cadmium (Cd), arsenic (As), copper (Cu), and lead (Pb) in surface and groundwater in Tinga, in the Bole-Bamboi District. A total of 42 water samples were collected for a period of six months. Mean concentration of Hg, Cd, and Pb were found to be (0.050 ± 0.04 mg/L), (0.031 ± 0.02 mg/L) and (0.07 ± 0.05 mg/L), respectively....

Author(s): Samuel Jerry Cobbina, Daniel Nkuah, Damian Tom-Dery and Samuel Obiri

Environmental metals pollutants load of a densely populated and heavily industrialized commercial city of Aba, Nigeria

January 2013

Diseases and their associated health defects are most often related to the quality of the total environment which in itself is also related to the quality and quantity of wastes generated in those areas, as partly defined by the nature of activities carried out by the populace. This environment-health relationship dynamics are particularly evident in most tropical environments like Nigeria where various environmental...

Author(s): Tobias I. Ndubuisi Ezejiofor, A. N. Ezejiofor, A. C. Udebuani, E. U. Ezeji, E. A. Ayalogbu, C. O. Azuwuike, L. A. Adjero, C. E. Ihejirika, C. O. Ujowundu, L. A. Nwaoguand K. O. Ngwogu

Determination of median lethal concentration (LC50) of copper sulfate and lead nitrate and effects on behavior in Caspian sea kutum (Rutilus frisii kutum)

January 2013

The aim of present study was to determine the LC50 value of in Caspian sea kutum. The results indicated that median lethal concentration (LC50) of Caspian sea kutum (Rutilus frisii kutum) for 24, 48, 72 and 96 h of exposure are 2.944, 2.756, 2.562 and 2.310 ppm, respectively and median lethal concentration (LC50) of lead to Caspian sea kutum (R. frisii kutum) for 24, 48, 72 and 96 h of exposure as...

Author(s): Esmail Gharedaashi, Mohammad Reza Imanpour and Vahid Taghizadeh

Toxicological assessments of the aqueous extract of Boswellia dalzielli stem bark on the liver and kidney of male mice

January 2013

The study was conducted to determine the phytochemical constituents and also to assess the toxicity of the aqueous extract of Boswellia dalzielli stem bark on the liver and kidney of male mice. Healthy male mice weighing between 45 to 50 g were used. The mice were grouped into four different groups, each containing four mice, respectively. Different concentrations (200, 400 and 600 mg/kg) of the aqueous...

Author(s): L. J. Goje, P. E. Ghamba, D. N. Bukbuk and I. Lai

Cytogenotoxicity effects of industrial effluents on Allium cepa root meristem: A review on positive results and problems of effective compliance to environmental legislations; the Nigeria perspective

December 2012

Most industries are sited with little or no consideration for environmental and social consequences, especially in developing countries. This has led to the discharge of genotoxic chemicals used for many purposes in the manufacturing processes into environmental compartments such as air, water, soil and sediments. Results of the cytotoxic and genotoxic assays of these wastewaters on Allium cepa root tip...

Author(s): Abu Ngozi E.

Effect of lead nitrate on survival rate and chronic exposure on growth performance of grass carp (Ctenopharyngodon idella)

December 2012

The acute toxicity of lead nitrate to grass carp (Ctenopharyngodon idella) juveniles was assessed in a static renewal bioassay for 96 h. In addition, an experiment was conducted to determine the growth performance during 60-day sublethal (Pb(NO3)2) exposure. The results indicated that median lethal concentration (LC50) of lead nitrate to Grass carp for 96 h of exposure was 246.455 µ. The chronic exposure to...

Author(s): Esmail Gharedaashi, Hamed Nekoubin, Alireza Asgharimoghadam, Mohammad Reza Imanpour and Vahid Taghizade

Cytotoxicity and genotoxicity of some agropesticides used in Southern Africa

December 2012

Pesticides use boosts agricultural yield by reducing crop losses. However, some pesticides are mutagens and active ingredients could produce different effects in different formulations. Wipe-out (WO) (Glyphosate 360 g/l), K-O Gard® (KOG) (Deltamethrin 10 g/l), Cutworm bait (CWB) (Sodium Fluosilicate, 100 g/kg), Snail ban (SB) (Metaldehyde, 30 g/kg and Carbaryl, 20 g/kg) and Coopex (CPX) (Permethrin 250...

Author(s): Asita, A. O. and Hatane, B. H

Packaging type and their effects on the chemical and microbial quality of Sudanese white cheese (Gibna bayda)

December 2012

The study was based on surveying ten samples of Sudanese white cheese packaged in two different containers (plastic and metal), collected from different supermarkets in Khartoum state. The comparison of chemical composition and microbial count was done. The experimental results showed that the average ash content, moisture, acidity, pH, and total solid content means were 7.00 ± 2.73, 45.00 ± 4.81, 0.85...

Author(s): Nazar Abdualaziz ElNasri, Samah Omer Sirag and Hassan Elsiddig Hag Elsafi

Oil spills and community health: Implications for resource limited settings

November 2012

Oil spillage has become of increased relevance in recent times because of the magnitude with which it occurs, the effects it has on the environment, and the quality of life of people residing in the affected areas. The World Health Organization (WHO) has drawn the attention of many member states to the burden of non-communicable diseases on the limited resources available to health. Much emphasis has been placed on...

Author(s): Albert SALAKO, Oluwafolahan SHOLEYE and Sunkanmi AYANKOYA

Acute haematological response of a cichlid fish Sarotherodon melanotheron exposed to crude oil

November 2012

The acute haematological response of a brackish water cichlid fish Sarotherodon melanotheronexposed to crude oil was evaluated. They were exposed for 96 h to crude oil concentrations of 0, 50, 125, 250, 375, and 500 mg/L of water obtained from the fish source. Haematological analyses were carried out at 12, 24, 48, 72, and 96 h, respectively. Haematological analysis revealed that the red blood cells (RBC),...

Author(s): Obemeata Oriakpono, Hart Aduabobo and Ekanem Wokoma

Toxic effects of heavy metals (cadmium plus mercury) on haematological parameters and DNA damage in Lates calcarifer

November 2012

The present study was carried out to evaluate the effects of toxic metals (cadmium plus mercury) on the haematology and DNA damage of fish, Lates calcarifer for every 24 h up to 96 h. A significant gradual decrease of haemoglobin (-35.01 to -24.11) and hematocrit (-35.01 to -31.78) was noted at acute concentration of cadmium plus mercury (3.0 ppm) as compared to that of control. The comet assay...

Author(s): D. Senthamilselvan, A. Chezhian, E. Suresh and R. Ezhilmathy

Genotoxic damage in oral epithelial cells induced by fluoride in drinking-water on students of Tula de Allende, Hidalgo, Mexico

October 2012

Fluoride (F-) compounds are present on the earth’s surface, water, volcanoes and are also a product of petrochemical and cement industries. Little amounts of F- are required for the formation of bones and enamel, however, according to World Health Organization (WHO), ingestion of over 1.5 mg/L of F- may be a health hazard due to the toxic effects on the kidney, liver and it may also cause dental or...


Phytochemical screening chemical composition and toxicity of Euphorbia regis-jubae (Webb & Berth)

October 2012

Plant-derived substances have recently become of great interest owing to their versatile applications. According to Ncube et al. (2008) medicinal plants are the richest bio-resource of drugs of traditional systems of medicine, modern medicines, nutraceuticals, food supplements, folk medicines, pharmaceutical intermediates, and chemical entities for synthetic drugs. Therefore, Euphorbia regis-jubae (Webb &...

Author(s): Fouzia HMIMID, Fatima Azzahra LAHLOU, Mohammed LOUTFI and Noureddine BOURHIM

Public health risks associated with apples and carrots sold in major markets in Osogbo, Southwest Nigeria

October 2012

This study investigated the public health risks associated with the consumption of carrots and apples sold in major markets in Osogbo metropolis, Osun State Nigeria. Hundred samples of the fruits (49 apples and 51 carrots) were obtained from  five randomly selected  spots in the four major markets, namely, Igbonna, Oke-fia, Alekuwodo, and Orisumbare in Osogbo metropolis. The samples were screened for microbial...

Author(s): M. A. Adeleke, A. O. Hassan, T. T. Ayepola, T. M. Famodimu, W. O. Adebimpe and G. O. Olatunde

A prospective clinical study of myocarditis in cases of paraphenylenediamine (hair dye) poisoning in Northern India

August 2012

Myocarditis is unheard of and unreported albeit dangerous complication of ingestion of hair dyes containing paraphenylenediamine. Hence, a prospective study was planned to assess the myocardial damage with regard to clinical profile and outcome with different treatment approaches in patients with oral ingestion of hair dye so that a treatment protocol could be established for this under recognized complication. This...

Author(s): JAIN P. K., SHARMA Awadhesh Kumar, AGARWAL Navnit, SENGAR N. S.,SIDDIQUI Mohd Zaki, SINGH Anurag Kumar and GABA Ripudaman

Acute and subacute toxicity of aqueous extract of leaves mixture of Aloe buettneri (Liliaceae), Dicliptera verticillata (Acanthaceae), Hibiscus macranthus (Malvaceae) and Justicia insularis (Acanthaceae) on Swiss mice and albinos Wistar female rats

August 2012

Aloe buettneri (Liliaceae), Justicia insularis (Acanthaceae), Hibiscus macranthus (Malvaceae) and Dicliptera verticillata (Acanthaceae) (ADHJ) are medicinal plants generally found in tropical and subtropical areas. The leaf mixture of these plants is used in the Western Region of Cameroon to increase fertility, regularize the menstrual cycle and to treat dysmenorrhoea or cases of...

Author(s): Pone K. B., Telefo, P. B., Gouado, I. and Tchouanguep, F. M.

Indicators for assessing progress made towards improving environmental health

June 2012

This paper presents some process indicators that would be indicative of noteworthy genuine efforts and progress made by third developing countries in improving their environmental health. There is a coordinated international effort to call upon governments, UN agencies and the private sector, to protect children from environmental threat. Indicators give countries a credible and useful way to assess the status of...

Author(s): Rajan R. PATIL and M. BAGAVANDAS

Evaluation of polycyclic aromatic hydrocarbons (PAHs) content in foods sold in Abobo market, Abidjan, Côte d’Ivoire

June 2012

This work was aimed to record the concentrations of eight polycyclic aromatic hydrocarbons (PAHs): (benzo[a]anthracene, benzo[b]fluoranthene, benzo[k]fluoranthene, benzo[a]pyrene, dibenzo[a,h]anthracene, indeno[1,2,3-c,d]pyrene, benzo[g,h,i]perylene and chrysene) in meats and fishes sold in Abobo market in Abidjan, Côte d’Ivoire. The amount of PAHs present in each sample was quantified...

Author(s): Pierre MANDA, Djédjé Sébastien DANO, Ehouan Stephane-Joel EHILE, Mathias KOFFI, Ngeussan AMANI and Yolande Aké ASSI

Developmental methylmercury exposure affects avoidance learning outcomes in adult zebrafish

May 2012

The present study investigated the neurobehavioral effects of embryonic exposure to methylmercury (MeHg) in zebrafish using avoidance conditioning as the behavioral paradigm. In this study, adult zebrafish developmentally exposed as embryos to 0.00, 0.01, 0.03, 0.1, or 0.3 µM of MeHg were trained and tested for avoidance responses. The results showed that control zebrafish hatched from embryos unexposed...

Author(s): Xiaojuan Xu, Crystal Lamb, Melanie Smith, Lillian Schaefer, Michael J. Carvan III, and Daniel N. Weber

Heavy metal contamination risk through consumption of traditional food plants growing around Bindura town, Zimbabwe

May 2012

Mining activities are a leading cause of heavy metal contamination of soils and food plants leading to health risk fears. The concentration of heavy metals in soils, Bidens pilosa and Fadogia ancylantha in the vicinity of Bindura town were investigated. Results show that heavy metal concentration of soils and plants found around Bindura town was higher than that of the control area where there were...

Author(s): P. Dzomba, S. Nyoni and N. Mudavanhu

In vitro antioxidant activities and inhibitory effects of aqueous extracts of unripe plantain pulp (Musa paradisiaca) on enzymes linked with type 2 diabetes and hypertension

April 2012

The dried plantain pulps were crushed and milled into flour (Raw flour), while a portion of its flour was reconstituted in boiling water to form a thick paste known locally in Western Nigeria as ‘amala’. This was dried and milled into ‘Amala’ flour. The aqueous extracts of raw and ‘amala’ flour were prepared (1 g/20 mL). The phenolic contents, vitamin C and antioxidant properties...

Author(s): Sidiqat A.Shodehinde and Ganiyu Oboh

Paraphenylenediamine induces apoptosis of Murine myeloma cells in a reactive oxygen species dependant mechanism

April 2012

Paraphenylenediamine (p-PD) is the main aromatic amine used in the formulation of hair dyes. Epidemiologic studies have suggested that the use of p-PD based hair dyes might be related to increase risk of human malignant tumors including multiple myeloma and hematopoietic cancers. However, the toxicity of p-PD on myeloma cells has not been well elucidated yet. Therefore, the association between the cytotoxicity of p-PD...

Author(s): Zineb Elyoussoufi, Norddine Habti, Said  Motaouakkil, and Rachida Cadi

Assessment of antioxidant capacity, proximate composition and inhibitory activity of unripe plantain (Musa paradisiaca) products on Fe2+ and sodium nitroprusside -induced oxidative stress in vitro

March 2012

This study sought to assess the proximate composition, antioxidant and inhibitory effect of unripe false horn plantain (Musa paradisiaca) products on Fe2+ and sodium nitroprusside (SNP) induced lipid peroxidation in rat’s pancreas. The EC50 of Fe2+ chelating, 2,2-diphenyl-1picrylhydrazyl (DPPH) and OH free radical scavenging ability were also determined. A portion of the unripe false horn plantain...

Author(s): Sidiqat Adamson Shodehinde and Ganiyu Oboh

Occupational health hazards of fabric bag filter workers' exposure to coal fly ash

March 2012

The objective of the study was to assess employees’ exposure to coal fly ash dust during the replacement of fabric bag filters in bag houses at a power station. Personal and environmental sampling were conducted on a random sample of workers. Samples that were in excess of occupational exposure limits (OEL) for respirable fly ash were analysed for toxic metals. Physical observations and a questionnaire were used...

Author(s): Jacobus Engelbrecht, Phanuel Tau and Charles Hongoro,

Characteristic levels of heavy metals in canned tuna fish

February 2012

Concentrations of metals (aluminium, cadmium, lead and mercury) were determined from canned tuna commercialized in Canada and India, by inductively coupled plasma - optical emission spectrometer (ICP-OES) and direct mercury analyzer (DMA 80). Higher concentration of Al (1.806 to 3.161 µg/g) and Hg (0.60 to 0.62 µg/g) were found in tuna processed from India. Cd and Pb ranged from 0.020 to 0.025 and 0.011 to...

Author(s): Mani Mahalakshmi, Srinivasan Balakrishnan, Kalyanasundram Indira and Muthukumarasamy Srinivasan  

Nanotechnology: Safety paradigms

January 2012

The versatile utilization of nanotechnology in a variety of products used in different spheres of daily life has made it quite popular. This is attributed due to the enhanced surface related properties of the nanoparticles. But these enhanced properties also make nanoparticles, biologically more active leading to unexpected and unanticipated consequences on interaction with biological systems which may be deleterious to...

Author(s): Ishan Das Rastogi,

Mycotoxins in animals: Occurrence, effects, prevention and management

January 2012

Globalization of the trade in agricultural commodities has contributed significantly to the discussion about potential hazards involved and has increased in particular the awareness of mycotoxins. Safety awareness in food and feed production has also risen due to the simple fact that methods for testing residues and undesirable substances have become noticeably more sophisticated and more available at all points of the...

Author(s): Manal M. Zaki, S. A. El-Midany, H. M. Shaheen and Laura Rizzi

Biochemical aspects and formation of phenolic compounds by coir pith degraded by Pleurotus sajor caju

January 2012

Coir pith is a byproduct of fibre extraction from coconut husk. Coir pith has been produced in large quantities and is dumped as waste as its bulk at the production site itself and disposal efforts are in vain owing to the quantity. Several biological, biochemical and microbial methods have been tried and are underway to degrade the coir pith into useful product. A basidiomycete fungus viz.  Pleurotus...

Author(s): Abesh Reghuvaran and Anita Das Ravindranath

Hot spot biomonitoring of marine pollution effects using cholinergic and immunity biomarkers of tropical green mussel (Perna viridis) of the Indonesian waters

December 2011

Selected biomakers, Cholinesterase (ChE) and phagocytic activities have been investigated with the exposed green mussel Perna viridis in Indonesian coastal waters. An operative effect-based monitoring on two polluted sites and one reference area were investigated for aquaculture enterprises and human health aspects. Between two heavily polluted sites, green mussels from Cilincing indicated a lower level of the...

Author(s): Khusnul Yaqin, Bibiana Widiati Lay, Etty Riani, Zainal Alim Masud and Peter-Diedrich Hansen

Attenuation of t-Butylhydroperoxide induced oxidative stress in HEK 293 WT cells by tea catechins and anthocyanins

December 2011

The health promoting properties of catechins and anthocyanins have been of great interest to researchers in the recent past due to their significant in vitro and in vivo antioxidant activities. Most research on anthocyanins has been based on berry anthocyanins. These potentially health enhancing pigments are also found in some Kenyan tea cultivars. An in vitro study was carried out to...

Author(s): Kerio L. C., Bend J. R., Wachira F. N., , Wanyoko, J. K. and Rotich M. K.

Bioremediation of diesel-contaminated soil using Bacillus sp. (strain TMY-2) in soil by uniform and non-uniform electro kinetic technology field

December 2011

Selected biomakers, Cholinesterase (ChE) and phagocytic activities have been investigated with the exposed green mussel Perna viridis in Indonesian coastal waters. An operative effect-based monitoring on two polluted sites and one reference area were investigated for aquaculture enterprises and human health aspects. Between two heavily polluted sites, green mussels from Cilincing indicated a lower level of the...

Author(s): A. Khodadadi, D. Yousefi, H. Ganjidoust and M. Yari

Occurrence and health implications of high concentrations of Cadmium and Arsenic in drinking water sources in selected towns of Ogun State, South West, Nigeria

December 2011

Selected biomakers, Cholinesterase (ChE) and phagocytic activities have been investigated with the exposed green mussel Perna viridis in Indonesian coastal waters. An operative effect-based monitoring on two polluted sites and one reference area were investigated for aquaculture enterprises and human health aspects. Between two heavily polluted sites, green mussels from Cilincing indicated a lower level of the...

Author(s): Abolanle Azeez A. Kayode, Joshua Olajiire Babayemi, Esther Omugha Abam and Omowumi Titilola Kayode

Methylene-tetrahydrofolate reductase (MTHFR) gene polymorphisms and bladder cancer susceptibility: A meta-analysis that includes race, smoking status and tumor stage

November 2011

Epidemiological studies have investigated that functional polymorphisms in methylene-tetrahydrofolate reductase (MTHFR) gene may play an essential role in bladder carcinogenesis, but the several published studies have reported inconclusive results. The objective of the current study is to conduct an update analysis investigating the association between polymorphisms in MTHFR gene and the risk of bladder cancer. We...

Author(s): Kamel Rouissi, Sami Khedhiri , Soumaya Kouidhi, Slah Ouerhani, Mohamed Cherif, and Amel Benammar-Elgaaied

Elucidate the origin of CYP flexible structural variation using molecular dynamics calculation

November 2011

Human cytochrome P450 1A2 (CYP1A2) plays a critical role in the mechanism of drug metabolism the understanding of which constitutes a cornerstone in drug design processes. Its relevance has furthered in view of recent trends in tailor made medicine, since the enzyme's activity differs according to the mutations orsingle nucleotide polymorphisms (SNP's) in the respective genetic coding region. Here...

Author(s): Mohamed Ismael and Carlos A. Del Carpio

Microbiological assessment and some physico-chemical properties of water sources in Akungba-Akoko, Nigeria

November 2011

A comparative study was carried out to determine the quality of three water sources: borehole, well and stream in Akungba-Akoko, Ondo State. The water sources were assessed for microbiological quality and physico-chemical properties (temperature, odor, color and pH). The stream had the highest plate count of 40 × 105 cfu/ml, while those of borehole and well water had the least of 12 × 105 cfu/ml...

Author(s): A. O. Ajayi and T. O. Adejumo

Ribosomal protein S3 gene expression of Chironomus riparius under cadmium, copper and lead stress

November 2011

Heavy metals are of interest because they are often present at significant levels in the environment and can have severe effects on the aquatic environment. To examine the effects of oxidative stress induced by heavy metals on chironomids, the full-length cDNA of ribosomal protein S3 (RpS3) from Chironomus riparius was determined using molecular cloning. The basal expression of the RpS3 gene was not affected...

Author(s): Kiyun Park and Inn-Sil Kwak

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