African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12496

Full Length Research Paper

Assessment of serum biochemistry in West African Dwarf (WAD) does administered varying levels of medroxyl–progesterone acetate (MPA), an estrus synchronizing drug

Imasuen, J. A.* and Otoikhian, C. S. O.    
Department of Animal Science, Faculty of Agriculture, Ambrose Alli University, P. M. B. 14, Ekpoma, Edo State, Nigeria.  
Email: [email protected]

  •  Accepted: 04 May 2011
  •  Published: 29 June 2011

Abstract

This study was carried out to assess the health status (serum biochemistry) of West African Dwarf (WAD) does administered varying levels of modroxyl-progestrone acetate (MPA), an oestrus synchronizing drug. The experiment was laid out in a completely randomized design. Result of the experiment showed that all the does were in good health status before, during and after the drug administration. Blood serum electrolytes analyses showed that all parameters assessed were within the normal range of a healthy goat. Sodium (Na+) mEq/L and potassium (K+) mEq/L were not significantly (P > 0.05) affected, by the drug administered. Urea (mg/dl) and creatinine (mg/dl) were significantly (P < 0.05) influenced by the drugs administered. Serum enzymes activities in WAD does showed that alanine transaminase (ALT) (m/L) and aspartate transaminase (AST) (m/L) were not significantly affected (P > 0.05) by administering MPA drug but alkaline phophatase (ALP) (mg/dl) was significantly (P < 0.05) influenced before and during the drug administration. Similarly, serum protein (g/dl) and serum glucose (mg/dl) values were significantly (P < 0.05) influenced before and during the drug administration. However, the result of this study showed that all the does were in good health status after synchronizing oestrus with the drug.

 

Key words: Serum biochemistry, West African Dwarf (WAD) does, oestrus synchronization drug.