African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12481

Full Length Research Paper

Some biological studies on Hypnea pannosa J. Ag.

Farah Mazhar1*, Mohtasheemul Hasan1, Iqbal Azhar1, M. Shaiq Ali2, Misbah Zubair1,  Rabail Zahid1 and Muhammad Akram3
1Department of Pharmacognosy, Faculty of Pharmacy, University of Karachi, Karachi-75270, Pakistan. 2H.E.J. Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan. 3Department of Basic Clinical Sciences, Faculty of Eastern Medicine, Hamadard University, Karachi-74600, Pakistan.
Email: [email protected]

  •  Accepted: 26 September 2011
  •  Published: 10 October 2011

Abstract

The present investigation focused on studying the toxicity, analgesic, behavioral and anti-emetic activities of the ethanol extract of Hypnea pannosa. The ethanol extract caused 100% lethality at the doses of 250 and 500 mg/kg. Significant analgesic and central depressant effects were observed from 150 mg/ kg dose. The extract at 200 mg/kg dose exhibited significant anti-emetic effect, when compared to standard drug.

 

Key words: Hypnea pannosa, toxicity, analgesic, behavioral, anti-emetic activities, crude extract.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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