African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12487

Full Length Research Paper

Association of Calpain 1 (CAPN1) and HRSP12 allelic variants in beef cattle with carcass traits

Guanyu Hou1,2#, Meng Huang2#, Xue Gao2, Junya Li2, Huijiang Gao2, Hongyan Ren2, Shangzhong Xu2*   # These authors contributed equally to the work.
1Tropical Crops Genetic Resources Institute, CATAS, Danzhou Hainan, 571737 2Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.
Email: [email protected]

  •  Accepted: 25 April 2011
  •  Published: 17 October 2011

Abstract

Calpain 1 (CAPN1) and its activator HRSP12 are evaluated as candidate gene for quantitative trait loci (QTLs) affecting meat tenderness. In this study, SNPs were detected by sequencing in 323 cattle from 9 breeds. The association results showed that the A3553G and T824C loci individually related with marbling and tenderness, and CAPN1/HRSP12 double homozygote and heterozygote/homozygote pairs (AA/TT, AA/CC, AG/TT and GG/TT) had higher marbling score than the other groups. Our findings suggest that polymorphisms inCAPN1 and HRSP12 might be the important genetic factor influencing meat quality in carcass trait.

 

Key words: Cattle, Calpain 1, HRSP12, association, carcass trait.