African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12496

Full Length Research Paper

Genetic polymorphisms of 17 Y-chromosome STRs in Han population from Henan province of China

  Hongyan Wu1*, Kejie Wang1, Lin Zhang1, Xihuan Zhang2, Lei Wang3 and Weihong Yang4
  1Xinxiang Medical University School of Basic Medical, Jinsui Road, Xinxiang, Henan 453000, People’s Republic of China. 2Henan Institute of Science and Technology, Jinsui Road, Xinxiang, Henan 453000, People’s Republic of China. 3Zhengzhou Municipal Public Security Bureau, Zhengzhou, Henan 450009, People’s Republic of China. 4Zhengzhou University School of Basic Medical, Jinsui Road, Zhengzhou, Henan 450052, People’s Republic of China.
Email: [email protected]

  •  Accepted: 08 April 2011
  •  Published: 11 July 2011

Abstract

 

Haplotypes and allele frequencies of 17 Y-short tandem repeats (STRs) included in the PowerPlex1 Y systems kit (DYS19, DYS389 I, DYS389 II, DYS390,DYS391, DYS392, DYS393, DYS385, DYS438, DYS439, DYS437,  DYS448, DYS456, DYS458, DYS635 and Y GATA H4) were examined in a population sample of 276 unrelated Han male living in Henan province. A total of 272 haplotypes were observed in the 276 individuals studied, of which 268 were unique and four were found in two individuals. The gene diversity values ranged from 0.5019 (DYS391) to 0.9579 (DYS385a, b). The overall haplotype diversity for the 17 Y-STR loci was 0.9998.

 

Key words: Y-chromosomal short tandem repeats (STRs), haplotype, genetic polymorphisms, Chinese Han population

Abbreviation

AMOVA, Analysis of molecular variance; STR, short tandem repeat; PCR, polymerase chain reaction; IBS, identity by state; ISFG, International Society of Forensic Genetics; GD, gene diversity; HD, haplotype diversity.