African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12487

Full Length Research Paper

Enhanced Phagocytosis and Antibody Production by Tinospora cordifolia - A new dimension in Immunomodulation

M. S. Ranjith1*, A.J.A. Ranjitsingh2, S. Gokul Shankar3, G. S. Vijayalaksmi5, K. Deepa5 and Harcharan Singh Sidhu1
1Microbiology Unit, AIMST University, Kedah, Malaysia. 2Department of Advanced Zoology and Biotechnology, Sri Paramakalyani College, Alwarkurichi, India. 3R and D Center, Cholayil Private Limited, Chennai, India. 4Sri Paramakalyani Center for Environmental Sciences, M.S. University, Tirunelveli, India. 5Anatomy Unit, AIMST University, Kedah, Malaysia.
Email: [email protected]

  •  Accepted: 18 December 2007
  •  Published: 18 January 2008

Abstract

Tinospora cordifolia (guduchi) is a widely used shrub in ayurvedic systems of medicine known to possess immunomodulatory properties. In the present study the aqueous extract of T. cordifolia was found to enhance phagocytosis in vitro. The aqueous and ethanolic extracts also induced an increase in antibody production in vivo.

 

Key words: Immunomodulation, phagocytosis assay, Tinospora cordifolia.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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