African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12487

Full Length Research Paper

Fumaric acid, an antibacterial component of Aloe vera L.

Chang-Liang He1, Ben-Dong Fu1#, Hai-Qing Shen1, Xiao-Lin Jiang1 and Xu-Bin Wei1*#
1Department of Clinical Veterinary Medicine, College of Animal Science and Veterinary Medicine, Jilin University, Xi'an Road 5333, Changchun, Jilin 130062, People’s Republic of China. 2Beijing Key Laboratory of Traditional Chinese Veterinary Medicine, Beijing University of Agriculture, Beijing 102206, People’s Republic of China.   #These  Authors contributed equally to this work.
Email: [email protected]

  •  Accepted: 15 March 2011
  •  Published: 11 April 2011

Abstract

The acetoacetate fraction partitioned from Aloe vera L. showed an effective antibacterial activity against four clinically frequent pathogenic bacteria. Through a series of chromatographic methods and activity assays, one compound was obtained and it has potent antibacterial activity. Based on the data of mass spectrometry, 1H-NMR, 13C-NMR and IR spectra, this compound was determined to be fumaric acid. This study concluded that fumaric acid is one of the antibacterial components in A. vera.

 

Key words: Fumaric acid, Aloe vera, antibacterial activity.