African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12496

Full Length Research Paper

Phytochemical and antimicrobial studies on stem bark extract of Sterculia setigera, Del.

T. A. Tor-Anyiin1,3*, M. U. Akpuaka1 and H. O. A. Oluma2
  1Department of Pure and Industrial Chemistry, Nnamdi Azikiwe University, Awka, Anambra State, Nigeria. 2Department of Biological Sciences, University of Agriculture, Makurdi, Benue State, Nigeria. 3Department of Chemistry, University of Agriculture, P.M.B. 2373 Makurdi, Benue State, Nigeria.
Email: [email protected]

  •  Accepted: 25 April 2011
  •  Published: 14 September 2011

Abstract

 

Antibacterial activity using broth and disc diffusion methods, and phytochemical screening was carried out on crude stem bark extracts of Sterculia setigera, a plant used ethnomedically by various communities in Nigeria. These extracts showed low antibacterial activity against Staphylococcus aureus, Proteus mirabilis andKlebsiella pneumonia. Phytochemical screening revealed the presence of alkaloids, phenolics/tannins in acetone and methanol extracts, and triterpenoid in boiling petroleum ether extract.

           

Key words:    Steculia setigera, extracts, antibacterial activity, alkaloids, triterpenoid, phenolics/tannins.

Abbreviation

PE, Petroleum ether; AC, acetone; ME, methanol; PEE, petroleum ether extract; ACE, acetone extract; MEE, methanol extract.