African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12487

Full Length Research Paper

An alternative caprine infection model for Mycoplasma mycoides

Ssajjakambwe Paul
  • Ssajjakambwe Paul
  • Department of Biotechnology, International Livestock Research Institute, Nairobi, Kenya.
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Elise Schieck
  • Elise Schieck
  • Department of Biotechnology, International Livestock Research Institute, Nairobi, Kenya.
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Anne Liljander
  • Anne Liljander
  • Department of Biotechnology, International Livestock Research Institute, Nairobi, Kenya.
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Tweyongyere Robert
  • Tweyongyere Robert
  • Animal Resources and Biosecurity, College of Veterinary Medicine, Makerere University Kampala, Kampala Uganda P. O. Box 7062, Kampala, Uganda.
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Matovu Enock
  • Matovu Enock
  • Animal Resources and Biosecurity, College of Veterinary Medicine, Makerere University Kampala, Kampala Uganda P. O. Box 7062, Kampala, Uganda.
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Kazibwe Ann
  • Kazibwe Ann
  • Animal Resources and Biosecurity, College of Veterinary Medicine, Makerere University Kampala, Kampala Uganda P. O. Box 7062, Kampala, Uganda.
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Nanteza Ann
  • Nanteza Ann
  • Animal Resources and Biosecurity, College of Veterinary Medicine, Makerere University Kampala, Kampala Uganda P. O. Box 7062, Kampala, Uganda.
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Mwiine Frank
  • Mwiine Frank
  • Animal Resources and Biosecurity, College of Veterinary Medicine, Makerere University Kampala, Kampala Uganda P. O. Box 7062, Kampala, Uganda.
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  •  Received: 25 July 2019
  •  Accepted: 25 October 2019
  •  Published: 31 December 2019

Abstract

Ruminant infection models for Mycoplasma mycoides are invasive and laborious factors that may interfere with the experiment outcomes. This brief review presents an alternative method that may minimize on the mentioned challenges earlier mentioned. M. mycoides subsp. capri GM12 and M. mycoides subsp. capri YCP1.1 ∆68 strains were used; the former, causing a septicemia in goats. An intra-tracheal inoculation technique was employed after aseptic preparation as an alternative to the common intubation method. The former is cheaper, less laborious to handlers, with minimal stress to goats and more time-efficient. In conclusion, this may be used as an alternative to the intubation method. The described technique here will be useful in contagious bovine pleuropneumonia and contagious caprine pleuropneumonia research with modifications, diseases for cattle and small ruminants, respectively.
 
Key words: Mycoplasma mycoides, animal infection model, ruminants.

Copyright © 2024 Author(s) retain the copyright of this article.

This article is published under the terms of the Creative Commons Attribution License 4.0

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