African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12488

Full Length Research Paper

Antidiabetic effect of aqueous extract of Basella alba leaves and metformin in alloxan-induced diabetic albino rats

Bamidele, O.*
  • Bamidele, O.*
  • Department of Physiology, Bowen University, Iwo, Osun State, Nigeria.
  • Search for this author on:
  • Google Scholar
Arokoyo, D. S.
  • Arokoyo, D. S.
  • Department of Physiology, Bowen University, Iwo, Osun State, Nigeria.
  • Search for this author on:
  • Google Scholar
Akinnuga, A. M.
  • Akinnuga, A. M.
  • Department of Physiology, Cross River University of Technology, Cross River, Nigeria.
  • Search for this author on:
  • Google Scholar
Oluwarole, A. O.
  • Oluwarole, A. O.
  • Department of Physiology, Bowen University, Iwo, Osun State, Nigeria.
  • Search for this author on:
  • Google Scholar


  •  Received: 19 March 2014
  •  Accepted: 12 May 2014
  •  Published: 11 June 2014

References

Ajala MO, Oladipo OO, Fasanmade O, Adewole TA (2003). Laboratory assessment of three glucometers. Afr. J. Med. Sci. 32:279-282.
 
Anandarajagopal K, Sudhahar D, Ajaykumar TV, Muthukumaran G (2011). Evaluation of CNS Depressant Activity of Aerial Parts of Basella alba Linn. J. Pharmacol. Toxicol. 1(5):1-6.
 
Aquilara FJA, Ramos RR, Gutierrez SP, Contreras AA, Weber CCC, Saeenz JLF (1998). Study of the anti-hyperglycemic effect of plants used as anti-diabetes. J. Ethnopharmacol. 61:101-110.
Crossref
 

Bamidele O, Akinnuga AM, Olorunfemi JO, Odetola OA, Oparaji CK, Ezeigbo N (2010). Effects of aqueous extract of Basella alba leaves on haematological and biochemical parameters in albino rats. Afr. J. Biotechnol. 9(41):6952-6955.

View
 
Carvalho EN, Carvalho NAS, Ferreira IM (2003). Experimental model of induction of diabetes mellitus in rats. Actacir. Bras. 18:60-64.
Crossref
 
Ceriellos A, Mortz E (2004). Is oxidative stress the pathogenic mechanism underlying insulin resistance, diabetes and cardiovascular disease? The common soil hypothesis revisited. Arterioscler. Thromb. Vasc. Biol. 24:816-823.
Crossref
 
Chaitanya KB (2012). Anti inflammatory activity of Basella alba Linn. in albino rats. J. Appl. Pharm. Sci. 2(4):87-89.
Crossref
 
Dhasarathan P, Theriappan P (2011). Evaluation of anti-diabetic activity of strychonous potatorium in alloxan-induced diabetic rats. Journal of Medicine and Medical Sciences. 2(2):670-674.
 
Duke JA, Ayensu ES (1985). Medicinal Plants of China Reference Publications, Inc. ISBN 0-917256-20-4.
 
Facciola S (1990). Cornucopia-A source Book of Edible Plants. Kampong Publications. ISBN 0-9628087-0-9. 2:183-187.
 
Grubben GJH, Denton OA (2004). Plant Resources of Tropical Africa 2. Vegetable. PROTA Foundation, Wageningen; Backhuys, Leiden; CTA, Wageningen. 4:103-111.
 
Kuete V, Efferth T (2010). Cameroonian medicinal plants: pharmacology and derived natural products. Front. Pharmacol. 25(1):123.
 
Kumar V, Bhat ZA, Kumar D, Khan NA, Chashoo IA, Irfat Ara (2012). Gastroprotective effect of leaf extracts of Basella alba var. against experimental gastric ulcers in rats. Revista Brasileira de Farmacognosia 22(3):657-662.
Crossref
 
Loew D, Kaszkin M (2002). Approaching the problem of bioequivalence of herbal medicinal products. Phytother. Res. 16(8):705-711.
Crossref
 
Nirmala A, Saraoja S, Vasanthi HR, Lalitha G (2009). Hypoglycaemic effects of Basella rubra in Streptozotocin-induced diabetic albino rats. J. Pharmacog. Phytother. 1(2):025-030.
 
Nirmala A, Saraoja S, Gayathri Devi G (2011). Antidiabetic activity of Basella rubra and its relationship with the antioxidant property. Br. Biotechnol. J. 1(1):1-9.
Crossref
 
Olajire AA, Azeez L (2011). Total antioxidant activity, phenolic, flavonoid and ascorbic acid contents of Nigerian vegetables. Afr. J. Food Sci. Technol. 2(2):022-029.
 
Olmendilla B, Granado F, Gil-Martinez E, Blanco I, Rojas-Hildago E (1997). Reference values from retinol, tocopherol and main carotenoids in serum of control and insulin dependent diabetic Spanish subjects. Clin. Chem. 43:1066-1071.
 
Oyewole OA, Kalejaiye OA (2012). The antimicrobial activities of Ethanolic extracts of Basella alba on selected microorganisms. Scien. J. Microbiol. 1(5):113-118.
 
Shareef SM, Sridhar I, Mishra SS, Venkata Rao Y (2013). Evaluation of hypoglycaemic effect of Lagerstroemia speciosa (Baraba) leaf extract in alloxan-induced diabetic rabbits. Int. J. Med. Res. Health Sci. 2(2):217-222.
Crossref
 
Stalin C, Dineshkumar P, Nithiyananthan K (2012). Evaluation of antidiabetic activity of methanolic leaf extract of Ficus carica in alloxan-induced diabetic rats. Asian J. Pharm. Clin. Res. 5(3):85-87.
 
Wang L, Luis S, Pradhan AD, Manson JE, Sesso HD (2006). Plasma lycopene, other carotinoid and the risk of type 2 diabetes in women. Am. J. Epidemol. 164:576-585.
Crossref
 
WHO, (1985). Diabetes mellitus: Report of a WHO Study Group. Geneva, World Health Org. Tech. Rep. Ser. 727.
 
World Medical Association (2002). Americal Physiological Society. Guiding principles for research involving animals and human beings. Am. J. Physiol. Reg. Integr. Comp. Physiol., 283: 281-283.
 
Zimmet PZ, Lefebvre P (1996). The global NIDDM epidemic. Diabetology 39: 1247-1248.
Crossref

 

Copyright © 2024 Author(s) retain the copyright of this article.

This article is published under the terms of the Creative Commons Attribution License 4.0

Back to Vol. 13 No. 24
Back to articles
SUBSCRIBE TO RSS
SUBMIT MANUSCRIPT
CONFERENCES