Full Length Research Paper
Abstract
The interaction between aminoglycosides-lysozyme and penicillin-lysozyme was studied by using UV and IR spectroscopy. The study was started with the purification of lysozyme from hen, quail, duck and pigeon and designated as HEWL, QEWL, DEWL and PEWL, respectively. Aminoglycosides (kanamycin and streptomycin) and penicillin (ampicillin) interactions with lysozyme were explored in this investigation. The study provides useful clinical information for the compatibility and use of drugs via the reaction mechanism at the molecule level.
Key words: UV and IR spectroscopy, lysozyme, aminoglycosides, penicillin.
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