African Journal of
Food Science

  • Abbreviation: Afr. J. Food Sci.
  • Language: English
  • ISSN: 1996-0794
  • DOI: 10.5897/AJFS
  • Start Year: 2007
  • Published Articles: 979

Full Length Research Paper

Health factors associated with persistent konzo in four villages in the Democratic Republic of Congo (DRC)

Banea J. P.
  • Banea J. P.
  • Programme National de Nutrition (PRONANUT), Kinshasa, Democratic Republic of Congo (DRC).
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Bradbury J. H.*
  • Bradbury J. H.*
  • Evolution, Ecology and Genetics (EEG) Research School of Biology, Australian National University, Canberra, ACT 0200, Australia.
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Nahimana D.
  • Nahimana D.
  • Programme National de Nutrition (PRONANUT), Kinshasa, Democratic Republic of Congo (DRC).
  • Google Scholar
Denton I. C.
  • Denton I. C.
  • Evolution, Ecology and Genetics (EEG) Research School of Biology, Australian National University, Canberra, ACT 0200, Australia.
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Foster M. P.
  • Foster M. P.
  • Evolution, Ecology and Genetics (EEG) Research School of Biology, Australian National University, Canberra, ACT 0200, Australia.
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Mekob N.
  • Mekob N.
  • Programme National de Nutrition (PRONANUT), Kinshasa, Democratic Republic of Congo (DRC).
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Kuwa N.
  • Kuwa N.
  • Programme National de Nutrition (PRONANUT), Kinshasa, Democratic Republic of Congo (DRC).
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Bokundabi G.
  • Bokundabi G.
  • Programme National de Nutrition (PRONANUT), Kinshasa, Democratic Republic of Congo (DRC).
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Foley W. J.
  • Foley W. J.
  • Evolution, Ecology and Genetics (EEG) Research School of Biology, Australian National University, Canberra, ACT 0200, Australia.
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  •  Received: 06 October 2015
  •  Accepted: 16 November 2015
  •  Published: 31 January 2016

References

Banea JP, Bradbury JH, Mandombi C, Nahimana D, Denton IC, Kuwa N, Tshala Katumbay D (2013). Control of konzo by detoxification of cassava flour in three villages in the Democratic Republic of Congo. Food Chem. Toxicol. 60:506-513.
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Banea JP, Bradbury JH, Mandombi C, Nahimana D, Denton IC, Foster MP, Kuwa N, Tshala Katumbay D (2015a). Konzo prevention in six villages in the DRC and the dependence of konzo prevalence on cyanide intake and malnutrition. Toxicol. Rep. 2:609-616.
crossref

 

Banea JP, Bradbury JH, Mandombi C, Nahimana D, Denton IC, Kuwa N, Tshala Katumbay D (2014b). Effectiveness of wetting method for control of konzo and reduction of cyanide poisoning by removal of cyanogens from cassava flour. Food Nutr. Bull. 35:28-32.
crossref

 

Banea JP, Bradbury JH, Nahimana D, Denton IC, Mashukano N, Kuwa N (2015b). Survey of the konzo prevalence of village people and their nutrition in Kwilu District, Bandundu Province, DRC. Afr. J. Food Sci. 9:43-50.
crossref

 

Banea M, Poulter NH, Rosling H (1992). Shortcuts in cassava processing and risk of dietary cyanide exposure in Zaire. Food Nutr. Bull. 14:137-143.

 

Banea-Mayambu JP, Tylleskar T, Tylleskar K, Gebre-Medhim M, Rosling H (2000). Dietary cyanide from insufficiently processed cassava and growth retardation in children in the Democratic Republic of Congo (formerly Zaire). Ann. Trop. Ped. 20:34-40.
crossref

 

Bokanga M, Ekanayake IJ, Dixon AGO, Porto MCM (1994). Genotype environment interactions for cyanogenic potential in cassava. Acta Hortic. 375:131-139.
crossref

 

Bradbury JH, Banea JP, Mandombi C, Nahimana D, Denton IC, Kuwa N 2015). Practical pointers for prevention of konzo in tropical Africa. (Field Exchange 50:62. Cardoso AP, Mirione E, Ernesto M, Massaza F, Cliff J, Haque MR, Bradbury JH (2005). Processing of cassava roots to remove cyanogens. J. Food Comp. Anal. 18:451-460.

 

Chabwine JN, Masheka C, Balol'ebwami Z, Maheshe B, Balegamire S, Rutega B, wa Lola M, Mutendela K, Bonnet MJ, Shangalume O, Balegasmire JM, Nemery B (2011). Appearance of konzo in South Kivu, a wartorn area in the Democratic Republic of Congo. Food Chem. Toxicol. 40:644-649.
crossref

 

Cliff J, Martensson J, Lundquist P, Rosling H, Sorbo B (1985). Association of high cyanide and low sulphur intake in cassava induced spastic paraparesis. Lancet 11:1211-13.
crossref

 

Cliff J, Muquingue H, Nhassico D, Nzwalo H, Bradbury JH (2011). Konzo and continuing cyanide intoxication from cassava in Mozambique. J. Chem. Toxicol. 49:631-635.
crossref

 

Cliff J, Nicala D, Saute F, Givragy R, Azambuja G, Taela A, Chavane L, Howarth J (1997). Konzo associated with war in Mozambique. Trop. Med. Int. Health 2:1068-1074.
crossref

 

Delhourne M, Mayans J, Calo M, Guyot-Bender C (2012). Impact of cross-sectoral approach to addressing konzo in DRC. Field Exchange No. 44:50-54.

 

Diasolua-Ngudi D (2015). 1000 days to prevent stunting among children in konzo affected areas. CCDN News, No. 25:10-11.

 

Ernesto M, Cardoso AP, Nicala D, Mirione E, Massaza F, Cliff J, Haque MR, Bradbury JH (2002). Persistent konzo and cyanogen toxicity from cassava in northern Moxambique. Acta Trop. 82:357-362.
crossref

 

Haque MR, Bradbury JH (1999). Simple method for determination of thiocyanate in urine. Clin. Chem. 45:1459-1464.

 

Howlett WP (1994). Konzo: A new human disease entity. Acta Trop. 375:323-329.
crossref

 

Howlett WP, Brubaker GR, Mlingi N, Rosling H (1990). Konzo, an epidemic upper motor neuron disease studied in Tanzania. Brain 113:223-235.
crossref

 

Interagency Workshop Report WFP-FAO (2008). Measures of Food Consumption–Harmonizing Methodologies. April 2008, Rome. Italy.

 

Kasongo E, Calo M (2011). A cross-sectoral approach to addressing konzo in DRC. Field Exchange, No 41:3-5.

 

Mbewe RK (2015). Konzo disease breaks out in Mongu's Kaote village. 

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Nhassico D, Muquingue H, Cliff J, Cumbana A, Bradbury JH (2008). Rising African cassava production, diseases due to high cyanide intake and control measures. J. Sci. Food Agric. 88:2043-2049.
crossref

 

Nzwalo H, Cliff J (2011). Konzo: from poverty, cassava and cyanogen intake to toxico-nutritional neurological disease. PloS Negl. Trop. Dis. 5(6):e1051.
crossref

 

Trolli G (1938). Paraplegie spastique epidemique, "Konzo" des indigenes du Kwango, In: G. Trolli, Ed., Resume des observations reunies, au Kwango, au sujet de deux affections d'origine indeterminee, Fonds reine Elisabeth, Brussels, pp. 1-36.

 

World Health Organisation (WHO) (1996). Konzo: a distinct type of upper motor neuron disease. Weekly Epidemiol. Rec. 71:225-232