African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5232

Full Length Research Paper

Antibacterial activity of fresh juice of Allium sativum (garlic) against multi – drug resistant isolates of Staphylococcus aureus

Ayazi M.1, Asadpour L.2*, Kazemi S.1 and Pourkhalili Sh.3
  1Young Researchers Club, Rasht Branch, Islamic Azad University, Rasht, Iran. 2Department of Veterinary Medicine, Islamic Azazd University Rasht Branch, Rasht, Iran. 3Department of Microbiology, Islamic Azazd University Rasht Branch, Rasht, Iran.
Email: [email protected]

  •  Accepted: 22 November 2011
  •  Published: 23 December 2011



Staphylococcus aureus causes a variety of infections in humans and animals. The growing emergence of drug - resistant pathogens led to the development of natural antimicrobials. In this study the antimicrobial effect of fresh garlic juice against multi – drug resistant S. aureus isolates has been studied. Antibacterial activity was measured by agar well diffusion method. All the test bacteria were found sensitive to the garlic juice. The minimum inhibitory concentration (MIC) of the fresh garlic juice against the test bacteria were ranging from 6.25 to 12.5% v/v and the minimum bactericidal concentration (MBC) ranging from 25 to 50% v/v. Based on this finding garlic juice possess significant antibacterial potency against multi-drug resistant isolates of S. aureus may be used as a natural therapeutic agent and antimicrobial preservative in food industry.


Key words: Antibacterial activity, MDR Staphylococcus aureus and garlic juice.