African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5210

Full Length Research Paper

In vitro antioxidant activities of polysaccharides from endophytic fungus Fusarium oxysporum Dzf17

Peiqin Li, Chao Luo, Weibo Sun, Shiqiong Lu, Yan Mou, Youliang Peng and Ligang Zhou*
College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, China.
Email: [email protected]

  •  Accepted: 09 December 2011
  •  Published: 30 December 2011



Three polysaccharides, namely exopolysaccharide (EPS), water-extracted mycelial polysaccharide (WPS) and sodium hydroxide-extracted mycelial polysaccharide (SPS), from the endophytic fungus Fusarium oxysporum Dzf17 were investigated for their in vitroantioxidant activities. Among them, SPS was the most active antioxidant component, and WPS exhibited moderate antioxidant activity. The median effective concentration (EC50) values of the polysaccharides were 162.38 μg/ml (for WPS), 63.37 μg/ml (for SPS) by DPPH radical scavenging activity assay, and 54.54 μg/ml (for WPS) and 44.91 μg/ml (for SPS) by using ferrous ions chelating activity assay. The polysaccharides from F. oxysporum Dzf17 could be an alternative source as the antioxidant components.


Key words: Antioxidant activity, polysaccharides, endophytic fungus, Fusarium oxysporum Dzf17.