Abstract

Pseudomonas aeruginosa is one of the most common causes of burn wound infections. The aim of this study was to determine the frequency of antibiotic resistance burn morbidity during September 2005 to October 2007. The incidence of multi-drug resistantP. aeruginosa infection was indicated in 9238 patients admitted to Tehran Reference Burn Hospital. Specimens were collected after admitting the patients in the hospital wards. Susceptibility test were performed for all isolate. Specimens were collected based on hospital policy and cultures were performed on each patient. Isolated strains were identified by using standard bacteriological methods for isolation and identification of the causative agents. P. aeruginosa was identified in 3012 (70.5%), Staphylococcus aureusin 581 (13.6%), Acinetobacter 426 (9.9%), the rest organisms were 279 (6%). Frequencies resistant of applied antibiotics were tobramycin (82%), ceftazidim (78%), ceftizoxime (82%), ciprofloxacin (72%), amikacin (73%), gentamycin (80%), tetracyclin (60%), teazabactam (81%) and cotrimocxazol (98%), respectively for P. aeruginosa. Due to the high multi resistant rate in pseudomonas infection, there is need to immediately revise the hospital policy in control of nosocomial infection and treatment strategy such as more efficient antiseptic agents or new antibiotics used to reduce the rate of multidrug resistant.

Key words: Pseudomonas aeruginosa, multidrug resistant, Tehran Burn Reference Hospital.