African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5232

Full Length Research Paper

Serologic evaluation of hepatitis B and D in patients with cirrhosis

Monireh Rahimkhani1*, Hossein Khavari-Daneshvar2 and Sara Jamali2
  1School of Allied of Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran. 2Cancer Research Centre, Tehran University of Medical Sciences, Imam Hospital. Tehran, Iran.
Email: [email protected]

  •  Accepted: 26 February 2011
  •  Published: 30 April 2011

Abstract

 

Hepatitis D is the important complication in cirrhotic patients. Diagnosis of hepatitis D is based on detection of HBSAg and HDV Ab titer determination. The present research was performed on a number of cirrhotic patients with the aim to assess the prevalence of hepatitis D and B. In present study all the cirrhotic patients who were referred to Gastroenterology and Endoscopy ward of Imam Khomeini hospital during a period of 18 months were included. The level of anti HDV Ab, anti HBS Ab and HBS Ag were determined by method of ELISA (Pishtaz Teb). In this study 60 cirrhotic patients were evaluated. 16 patients were HBS Ag positive with mean age of 51.9 years, and from this group, 13 patients were anti HBC positive with mean age of 53.23 years and from this group, 8 patients were HDV Ab positive with mean age of 49 years. Hepatitis D remains as one of the problems in developing countries. By timely screening of cirrhotic patients for HDV, patients could undergo additional treatments.

 

Key words: Liver cirrhosis, hepatitis D, hepatitis B, HBS Ag, HBC Ab, HDV Ab.