African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5233

Full Length Research Paper

Phytochemical screening and antifungal activity of leaves extracts of Luffa cylindrica (Roem)

Mercy Itohan Aboh
  • Mercy Itohan Aboh
  • Department of Microbiology, Human Virology and Biotechnology, National Institute for Pharmaceutical Research and Development, Idu, P. M. B. 21 Garki Abuja, Nigeria.
  • Google Scholar
Peters Oladosu
  • Peters Oladosu
  • Department of Microbiology, Human Virology and Biotechnology, National Institute for Pharmaceutical Research and Development, Idu, P. M. B. 21 Garki Abuja, Nigeria.
  • Google Scholar
Gbonbola Adeshina
  • Gbonbola Adeshina
  • Department of Pharmaceutics and Pharmaceutical Microbiology, Faculty of Pharmaceutical Sciences, Ahmadu Bello University, Zaria, Kaduna State, Nigeria.
  • Google Scholar
Busayo Olayinka
  • Busayo Olayinka
  • Department of Pharmaceutics and Pharmaceutical Microbiology, Faculty of Pharmaceutical Sciences, Ahmadu Bello University, Zaria, Kaduna State, Nigeria.
  • Google Scholar
Stephen Olayeni Olonitola
  • Stephen Olayeni Olonitola
  • Department of Microbiology, Faculty of Life Science, Ahmadu Bello University, Zaria, Kaduna State, Nigeria.
  • Google Scholar


  •  Received: 20 September 2017
  •  Accepted: 21 October 2017
  •  Published: 21 December 2017

References

Abad MJ, Ansuategui M, Bermejo P (2007). Active antifungal substances from natural sources. Arch. Org. Chem. 7:116-145.

 

Aberkane A, Cuenca-Estrella M, Gomez-Lopez A, Petrikkou E, Mellado E, Monzon A, Rodriguez-Tudela J, Eurofung LN (2002). Comparative evaluation of two different methods of inoculum preparation for antifungal susceptibility testing of filamentous fungi. J. Antimicrob. Chem. 50:19-22.
Crossref

 
 

Abirami SM, Indhumathy R, Sashikala DG, Kumar DS, Sudarvoli M, Nandini R (2011). Evaluation of the wound healing and anti-inflammatory activity of whole plant of Luffa cylindrica (Linn). in rats. Pharmacol. Online 3:281-285.

 
 

Aboh MI, Okhale SE, Ibrahim K (2012). Preliminary studies on Luffa cylindrica: Comparative phytochemical and antimicrobial screening of the fresh and dried aerial parts. Afr. J. Microbiol. Res. 6(13):3088-3091.

 
 

Aboh MI, Olayinka BO, Adeshina GO, Oladosu P (2014). Antifungal activities of phyto compounds from Mitracarpus villosus (Sw.) DC aerial parts obtained from Abuja, Nigeria. Malays. J. Micro. 10(2):133-138.

 
 

Ahmad A, Alkarkhi A, Hena S, Khim LH (2009). Extraction, separation and identification of chemical ingredients of Elephantopus scaber L. using factorial design of experiment. Int. J. Chem. 1(1):36- 49.
Crossref

 
 

Ahmad B, Khan AA (2013). Antibacterial, antifungal and phytotoxic activities of Luffa cylindrica and Momordica charantia. J. Med. Plants Res. 7(22):1593-159

 
 

Aladejimokun AO, Adesina IA, Falusi VO, Edagbo DE (2014). Comparative study of antimicrobial potency and phytochemical analysis of methanolic extracts of the leaf and flower of Luffa cylindrica. J. Nat. Sci. Res. 4(8):7-10.

 
 

Aliero AA, Wara SH (2009). Validating the medicinal potential of Leptadenia hastata. Afr. J. Pharm. Pharmacol. 3(6):335-338.

 
 

Dzoyem JP, Tchuenguem RT, Kuiate JR, Teke GN, Kech, FA, Kuete V (2014). In vitro and in vivo antifungal activities of selected Cameroonian dietary spices. BMC Complem. Altern. Med. 14(58):1-8.
Crossref

 
 

Etuk EU, Suberu, HA, Ameh, IG, Abubakar K (2008). Antimycotic effect of the aqueous leaf extract of Pterocarpus erinaceus in rats. J. Pharm. Toxic. 3:318-323.
Crossref

 
 

Evans WC (2004). Trease and Evans Pharmacognosy. WB Saunders Ltd. London, pp. 32-33, 95-99, 512, 547.

 
 

Hefferon KL (2012). Plant-made vaccines. J. Vac. Vaccin. 3(4):108.
Crossref

 
 

Kreander B, Vuorela KP, Tammela P (2002). A rapid screening method for detecting active compounds against erythromycin-resistant bacterial strains of Finnish origin. Fol. Microbiol. 50(6):487-493.
Crossref

 
 

Kullberg B, Filler S (2002). Candidemia: In Candida and Candidiasis. ASM Press, Washington DC. 2002:327-340.

 
 

Masoko P, Eloff JN (2005). The diversity of antifungal compounds of six South African Terminalia species (Combretaceae) determined by bioautography. Afr. J. Biotechnol. 4(12):1425-1431.

 
 

Mhya DH, Mankilik M (2014). Phytochemical screening of aqueous extract of Luffa aegyptiaca (sponge gourd) leave sample from Northern Nigeria: A short communication. Int. J. Pharmaceut. Sci. Res. 5(7):344-345.

 
 

Olowosulu AK, Ibrahim YKE, Bhatia PG (2005). Studies on the antimicrobial properties of formulated creams and ointments containing Baphia nitida heartwood extract. J. Pharm. Biores. 2(2):124-130.

 
 

Otimenyin SO, Uguru MO, Ogbonna A (2008). Antimicrobial and hypoglycemic effects of Momordica balsamina. Linn. J. Nat. Prod. 1:103-109.

 
 

Partap S, Kumar AS, Neeraj K, Jha KK (2012). Luffa cylindrica: An important medicinal plant. J. Nat. Prod. Pl. Res. 2(1): 127-134.

 
 

Pereira F, Paulo Alves Wanderley PA, Viana FAC, Baltazar de Lima R, Barbosa de Sousa F, Lima E (2011). Growth inhibition and morphological alterations of Trichophyton rubrum induced by essential oil from Cymbopogon winterianus Jowitt ex Bor. Braz. J. Microbiol. 42(1):233-242.
Crossref

 
 

Prashant T, Bimlesh K, Mandeep K, Gurpreet K, Harlee, K (2011). Phytochemical screening and extraction: A review. Int. Pharm. Sci. 1(10):998-106.

 
 

Sashikala GD, Kottai AM, Satheesh DK, Rekha S, Indhumathy NR (2009). Studies on the antibacterial and antifungal activities of the ethanolic extracts of Luffa cylindrica (Linn) fruit. Int. J. Drug Dev. Res. 1(1):105-109.

 
 

Scorzoni L, de Paula e Silva ACA, Marcos CM, Assato PA, de Melo WCMA, de Oliveira HC, Costa-Orlandi CB, Mendes-Giannini MJS and Fusco-Almeida AM (2017). Antifungal Therapy: New Advances in the Understanding and Treatment of Mycosis. Front. Microbiol. 8:36.
Crossref

 
 

Shafi S, Singh S, Haider D, Mahendhar R, Alam MS, Swamy GN, Kumar HMS (2013). Synthesis of triazole and isoxazole based novel unsymmetrical biheterocycles. J. Hetero. Chem. 50(2):361-365.
Crossref

 
 

Sharma BC (2012). In vitro antibacterial activity of certain folk medicinal plants from Darjeeling Himalayas used to treat microbial infections. J. Pharmacogn. Phytochem. 2(4):1-4.

 
 

Senguttuvan J, Paulsamy S, Krishnamoorthy K (2013). In vitro antifungal activity of leaf and root extracts of the medicinal plant, Hypochaeris radicata. Int. J. Pharm. Pharmaceut. Sci. 5(3):758-761.

 
 

Sofowora A (2002). Medicinal Plants and Traditional Medicine in Africa. 3rd Edn. Spectrum Books Limited, Ibadan, Nigeria, pp. 1-153.

 
 

Souza ACO, Amaral AC (2017). Antifungal therapy for systemic mycosis and the nanobiotechnology era: Improving efficacy, biodistribution and toxicity. Front. Microbiol. 8:336.
Crossref

 
 

Thamaraiselvi PL, Jayanthi P (2012). Preliminary studies on phytochemicals and antimicrobial activity of solvent extracts of Eichhornia crassipes (Mart.) Solms. Asian J. Plant Sci. Res. 2(2):115-122.

 
 

Zohra M, Fawzia A (2011). Impact of solvent extraction type on total polyphenols content and biological activity from Tamarix aphylla (l.) Karst. Int. J. Pharm. Bio. Sci. 2(1):609- 615.