African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2296

Full Length Research Paper

Evaluation of antibacterial activity of Morinda citrifolia, Vitex trifolia and Chromolaena odorata

S. Esath Natheer1*, C. Sekar1, P. Amutharaj1, M. Syed Abdul Rahman2 and K. Feroz Khan2
1Department of Microbiology, Faculty of Science, Annamalai University, Annamalai Nagar – 608 002, Tamil Nadu, India. 2Department of Marine Microbiology, Faculty of Marine Sciences, Annamalai University, Parangipettai – 608 502, Tamil Nadu, India.
Email: [email protected]

  •  Accepted: 15 February 2012
  •  Published: 22 March 2012

Abstract

Methanol, ethanol and ethyl acetate extracts of Morinda citrifolia L. (fruit, leaf and stem), Vitex trifolia and Chromolaena odorata (leaf) were prepared to evaluate the anti-bacterial activity. The antibacterial activities of extracts were tested against 12 bacterial isolates by in vitro disc diffusion method. Methanol extracts possessed higher level of antibacterial activity than ethanol and ethyl acetate extracts. When the plants were compared, C. odorata had better antibacterial activity than V. trifolia and M. citrifolia with the minimal inhibitory concentration (MIC) of about 25 mg/ml.

 

Key words: Antibacterial activity, disc diffusion method, Chromolaena odorataMorinda citrifolia L., Vitex trifolia.