Abstract

Malaria remains a disease of public health concern, which is associated with high mortality and morbidity, particularly in sub-Saharan Africa. This picture is mainly due to low effectiveness of antimalarials at the community level, a scenario caused by different factors related to the availability, quality, and efficacy of antimalarials as well as the degree of the patients’ and providers’ adherence to evidence-based recommendations about malaria treatment. This review presents an overview of the problem of low community effectiveness of antimalarials in sub-Saharan Africa, with a focus on the various causes as well as potential strategies to combat the problem.

Key words: Antimalarials, sub-Saharan Africa, disease, high mortality and morbidity.