African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2286

Full Length Research Paper

Effect of Angelica sinensis aqueous extract on uterus, ovary NF-kB/β-actin and IL-6/β-actin mRNA expression level in pelvic inflammation model rats

Chunyan Huang1, Xiaoping Chen2*, Hongmei Liu2, Xinping Ren2 and JinLing Xue2
1Department of Obstetrics and Gynecology, WuXi 4th People Hospital, JiangSu, China. 2Department of Obstetrics and Gynecology, YanCheng 1st People Hospital, YanCheng City 224000 Jiangsu, China.
Email: [email protected]

  •  Accepted: 09 February 2012
  •  Published: 22 March 2012

Abstract

Angelica sinensis is a Chinese medicinal herb for treating gynecological and gastrointestinal disorders and also in conjunction with cancer chemotherapy. In the present study, the effects of A. sinensis aqueous extract on uterus, ovary NF-kB/β-actin and IL-6/β-actin mRNA expression level in Pelvic inflammation model rats were investigated. Results showed that A. sinensis aqueous extract could significantly decreased uterus NF-kB/β-actin and IL-6/β-actin mRNA expression level in Pelvic inflammation rats.

 

Keywords: Pelvic inflammation, rat, Angelica sinensis, NF-kB/β-actin, IL-6/β-actin.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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