African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2285

Full Length Research Paper

Effect of co-administration of artemether and nevirapine on haematological parameters in normal and immunosuppressed Wistar rats

S. B. Anafi*
  • S. B. Anafi*
  • Department of Pharmacology & Therapeutics Faculty of Pharmaceutical Sciences, Ahmadu Bello University, Main Campus, P.M.B. 1045, Samaru, Zaria 810271, Kaduna State, Nigeria.
  • Google Scholar
H. O. Kwanashie
  • H. O. Kwanashie
  • Department of Pharmacology & Therapeutics Faculty of Pharmaceutical Sciences, Ahmadu Bello University, Main Campus, P.M.B. 1045, Samaru, Zaria 810271, Kaduna State, Nigeria.
  • Google Scholar
J. A. Anuka
  • J. A. Anuka
  • Department of Pharmacology & Therapeutics Faculty of Pharmaceutical Sciences, Ahmadu Bello University, Main Campus, P.M.B. 1045, Samaru, Zaria 810271, Kaduna State, Nigeria.
  • Google Scholar
H. M. Muktar
  • H. M. Muktar
  • Department of Haematology and Blood Transfusion, Ahmadu Bello University Teaching Hospital, Shika, P.M.B. 06, Kaduna State, Nigeria.
  • Google Scholar
A. S. Agbaji
  • A. S. Agbaji
  • National Research Institute for Chemical Technology, P.M.B. 1052, Zaria, Kaduna State, Nigeria.
  • Google Scholar


  •  Received: 19 February 2013
  •  Accepted: 23 September 2014
  •  Published: 22 October 2014

References

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Akomolafe RO, Adeoshun IO, Fakunle JB, Iwalewa EO, Ayoka AO, Ajayi OE, Odeleye OM, Akanji BO (2011). Effects of Artemether on the Plasma and Urine Concentrations of some Electrolytes in Rats. Afr. J. Biotechnol. 10(20):4226-4233.
 
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Nwonu CS, Akah PA, Ndu OO, Ezike AC, Onyekwelu NI (2008). Phar-macokinetic Evaluation of Drug Interactions between Cotrimoxazole and Zidovudine in Rabbits. Int. J. Trop. Med. 3(2):30-35.
 
Odunukwe N, Idigbe O, Kanki P, Adewole T, Onwujekwe D, Audu R, Onyewuche J (2005). Haematological and biochemical response to treatment of HIV-1 infection with a Combination of Nevirapine + Stavudine + Lamivudine in Lagos Nigeria. Turk. J. Haematol. 22(3):125-131.
 
Osonuga IO, Osonuga OA, Osonuga A, Onadeko AA, Osonuga AA (2012). Effect of Artemether on Haematological Parameters of Healthy and Uninfected Adult Wistar Rats. Asian Pacif. J. Trop. Biomed. 2(6):493-495.
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Soyinka JO, Onyeji CO, Omoruyi SI, Owolabi AR, Sarma PV, Cook JM (2009). Effects of Concurrent Administration of Nevirapine on the Disposition of Quinine in Healthy Volunteers. J. Pharm. Pharmacol. 61(4):439-443.
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Sule OJ, Elekwe I, Ayaogu EO (2012). Effect of Acalypha wilhesiana Muel Arg. On Haematolgical Parameters in Wistar Albino Rats. Int. J. Biol. Med. Res. 3(1):1234-1237.
 
Umar RA, Hassan SW, Ladan MJ, Matazu IK, Shehu B, Shehu RA, Muhammed LG Molabo FI (2008). Adverse Hepatic Effects Associated with Administration of Antiretroviral Drugs (Nevirapine, Lamivudine and Stavudine) to Albino Rats: Implication for Management of Patients with HIV/AIDS. Asian J. Biochem. 3:19-25.
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