International Journal of
Nutrition and Metabolism

  • Abbreviation: Int. J. Nutr. Metab.
  • Language: English
  • ISSN: 2141-2332
  • DOI: 10.5897/IJNAM
  • Start Year: 2009
  • Published Articles: 128

Full Length Research Paper

Effect of Commiphora swynnertonii resin on liver functions and levels of plasma glucose and lipids in carbon-tetrachloride treated chickens

Maghembe R. S.
  • Maghembe R. S.
  • Department of Biochemistry, Molecular Biology and Biotechnology, College of Veterinary and Medical Sciences, Sokoine University of Agriculture, P. O. Box 3017, Morogoro, Tanzania.
  • Google Scholar
G. G. Bakari
  • G. G. Bakari
  • Department of Physiology, Pharmacology and Toxicology, College of Veterinary and Medical Sciences, Sokoine University of Agriculture, P. O. Box 3017, Morogoro, Tanzania.
  • Google Scholar
R. A. Max
  • R. A. Max
  • Department of Biochemistry, Molecular Biology and Biotechnology, College of Veterinary and Medical Sciences, Sokoine University of Agriculture, P. O. Box 3017, Morogoro, Tanzania.
  • Google Scholar
S. T. Balthazary
  • S. T. Balthazary
  • Department of Biochemistry, Molecular Biology and Biotechnology, College of Veterinary and Medical Sciences, Sokoine University of Agriculture, P. O. Box 3017, Morogoro, Tanzania.
  • Google Scholar


  •  Received: 02 March 2017
  •  Accepted: 17 July 2017
  •  Published: 31 August 2017

References

Adebayo AH, Aliyu R, Gatsing D, Garba IH (2006). Effects of ethanolic leaf extracts from Commiphora africana (Burseraceae) on lipid profile in rats. Int. J. Pharmacol. 2(6):618-622.
Crossref

 

Ahmad A, Raish M, Ganaie MA, Ahmad SR, Mohsin K, Al-Jenoobi F, Al-Mohizea AM, Alkharfy KM (2015). Hepatoprotective effect of Commiphora myrrha against d-GalN/LPS-induced hepatic injury in a rat model through attenuation of pro inflammatory cytokines and related genes. Pharm. Biol. 53(12):1759-1767.
Crossref

 

Al-Amoudi NS (2010). Influence of esparto grass (Cortaderia sellona L.) myrrh (Commiphora myrrha L.), Fenugreek (Trigonella foenum Graecum L.) on reducing serum glucose of alloxan diabetic rats. Int. J. Food Nutr. Public Health 3:171-181.

 

Al-Howiriny TA, Al-Sohaibani MO, Al-Said MS, Al-Yahya MA, El-Tahir KH, Rafatullah S (2004).Hepatoprotective properties of Commiphora opobalsamum ("Balessan"), a traditional medicinal plant of Saudi Arabia. Drugs Exp. Clin. Res. 30(5-6):213-20.

 

Bakari GG, Max RA, Mdegela HR, Phiri EC, Mtambo MM (2013). Efficacy of resinous extract from Commiphora swynnertonii (Burrt) against Newcastle infection in chickens. Int. J. Med Plants Res. 2:156-161.

 

Bakari GG, Max RA, Mdegela, HR, Phiri, EC, Mtambo MM (2011). Antibacterial and antifungal activity of Commiphora swynnertonii (Burt) on Selected Pathogens of Public Health Importance. Res. J. Biomed. Sci. 6:175-179.

 

Bakari GG, Max RA, Mdegela RH, Pereka AE, Phiri ECJ, Mtambo MMA (2015).Effect of resinous extract from Commiphora swynnertonii (Burrt) on t on various physiological parameters in chickens. J. Med. Plants Res. 9(13):462-470.
Crossref

 

Burstein M (1970). HDL cholesterol determination after separation high density lipoprotein. Lipid Res. 11:583.

 

Cui J, Huang L, Zhao A, Lew JL, Jinghua Y, Sahoo S, Meinke PT, Royo I, Pelaez F, Wrught SD (2003). Guggulsterone Is a Farnesoid X Receptor Antagonist in Coactivator Association Assays but Acts to Enhance Transcription of Bile Salt Export Pump. J. Biol. Chem. 278:10214-10220.
Crossref

 

Deng R (2007). Therapeutic Effects of Guggul and Its Constituent Guggulsterone: Cardiovascular Benefits. Cardiovasc. Ther. 25(4):375-390.
Crossref

 

Fossati P, Prencipe L (1982). Serum triglycerides determined colorimetrically with an enzyme that produces hydrogen peroxide. Clin. Chem. 28:2077-2080.

 

Friedewald WT, Levy RI, Fredrickson DS (1972) Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin. Chem. 18:499-502.

 

Goji ADT, Dikko AAU, Bakari AG, Mohammed A, Ezekiel I, Tanko Y (2009). Effect of Aqueous-ethanolic Stem Bark Extract of Commiphora africana on Blood Glucose Levels on Normoglycemic Wistar Rats. Int. J. Anim. Vet. Adv. 1:22-24

 

Hassan NAM, Helala OK, Mansya, AE (2013). Hepatoprotective and Antioxidant Effects of Commiphora against CCl4-Induced Liver Injury in Adult Male Albino Rats. Int. J. Toxicol. Pharmacol. Res. 5:79-86.

 

Kalala W, Magadula J, Mdegela H (2014). Evaluating acaricidal activity of Commiphora swynnertonii (Burrt) bark exudate against common ticts in Tanzania. Int. J. Herbal Med. 2:19-25.

 

Kayombo EJ, Mahunnah RLA, Uiso FC (2013). Prospects and Challenges of Medicinal Plants Conservation and Traditional Medicine in Tanzania. 
Crossref

 

Ojha S, Bhatia J, Arora S, Golechha M, Kumari S, Arya DS (2011). Cardioprotective effects of Commiphora mukul against isoprenaline-induced cardiotoxicity: a biochemical and histopathological evaluation. J. Environ. Biol. 32:731-738.

 

Ramesh B, Saralakumari D (2012). Antihyperglycemic, hypolipidemic and antioxidant activities of ethanolic extract of Commiphora mukul gum resin in fructose-fed male Wistar rats. J. Physiol. Biochem. 68:573-582.
Crossref

 

Ruffo CK, Birnie A, Tengnäs B (2002). Edible wild plants of Tanzania.Regional Land Management Unit (RELMA). Technical Handbook Series 27. Nairobi, Kenya. Swedish International Development Agency (SIDA). P 766.

 

Saimo MK, Bizimenyera ES, Bwanika A, Ssebuguzi F, Weny G, Lubega GW (2003). Ethno veterinary practices in Uganda: Use of medicinal plants in treating helminthosis and coccidiosis in rural poultry and goats in Uganda. Bull. Anim. Health Prod. Afr. 51(3):133-138

 

Sharma B, Salunke R, Srivastava S, Majumder C, Roy P (2009). Effects of guggulsterone isolated from Commiphora mukul in high fat diet induced diabetic rats. Food Chem. Toxicol. 47:2631-2639.
Crossref

 

Sharma P, Sharma JD (2001). In vitro hemolysis of human erythrocytes-by plant extracts with antiplasmodial activity. J. Ethnopharmacol. 74(3):239-243.
Crossref

 

Shen T, Li GH, Wang XN, Lou HX (2012). The genus Commiphora: a review of its traditional uses, phytochemistry and pharmacology. J. Ethnopharmacol. 142:319-330.
Crossref

 

Trinder P (1969). Determination of glucose in blood using glucose oxidase with an alternative oxygen acceptor. Assoc. Clin. Biochem. 6:24-28.
Crossref

 

Urizar NL, Liverman AB, Dodds DT, Silva FV, Ordentlich P, Yan Y, Gozalez FJ, Heyman RA, Mangelsdorf D, Moore DD (2002). A natural product that lowers cholesterol as an antagonist ligand for FXR. Science 296:1703-1706.
Crossref

 

Wang X, Greiberger J, Ldinski G, Kager G, Paigen B, Jugens G (2004).The hypolipidemic natural product Commiphora mukul and its component guggulsterone inhibit oxidative modification of LDL. Atherosclerosis 172:239-246.
Crossref

 

WHO (1996). WHO monographs on selected medicinal plants. pp. 1-279.

 

Yang DJ, Yang D, Shi D, Xiao D, Chen YTC, Black C, Deng R, Yan B (2012). Hypolipidemic agent Z-guggulsterone: metabolism interplays with induction of carboxylesterase and bile salt export pump. J. Lipid Res. 53:529-539.
Crossref

 

Yerima M, Maje IM, Mahdi MA, Haruna ZB, Khan F, Tanko Y (2012). Effects of the stem-bark extract of Commiphora kerstingii Engl. on alloxan-induced hyperglycaemia and fructose induced insulin resistance. Nigerian J. Pharmacol. Sci. 11:80-86.