Journal of
Diabetes and Endocrinology

  • Abbreviation: J. Diabetes Endocrinol.
  • Language: English
  • ISSN: 2141-2685
  • DOI: 10.5897/JDE
  • Start Year: 2010
  • Published Articles: 69

Full Length Research Paper

GSTM1 and T1 null variants effects on the predisposition to type 2 diabetes mellitus in Turabah population, Saudi Arabia

Adil Mergani
  • Adil Mergani
  • Department of Molecular Genetics, College of Applied Medical Sciences-Turabah, Taif University, Saudi Arabia.
  • Google Scholar
Ahmed A. Mansour
  • Ahmed A. Mansour
  • Department of Molecular Genetics, College of Applied Medical Sciences-Turabah, Taif University, Saudi Arabia.
  • Google Scholar
Osama M. Saleh
  • Osama M. Saleh
  • Department of Molecular Genetics, College of Applied Medical Sciences-Turabah, Taif University, Saudi Arabia.
  • Google Scholar
Rasha N. Zahran
  • Rasha N. Zahran
  • Department of Molecular Genetics, College of Applied Medical Sciences-Turabah, Taif University, Saudi Arabia.
  • Google Scholar
Adil M. Mustafa
  • Adil M. Mustafa
  • Department of Molecular Genetics, College of Applied Medical Sciences-Turabah, Taif University, Saudi Arabia.
  • Google Scholar
Mukhtar A. Mohammed
  • Mukhtar A. Mohammed
  • Department of Molecular Genetics, College of Applied Medical Sciences-Turabah, Taif University, Saudi Arabia.
  • Google Scholar
Tamer Askar
  • Tamer Askar
  • Department of Molecular Genetics, College of Applied Medical Sciences-Turabah, Taif University, Saudi Arabia.
  • Google Scholar


  •  Received: 08 October 2017
  •  Accepted: 17 December 2018
  •  Published: 31 October 2022

References

Al-Mayah AIA (2014). Association between GSTT1 and GSTM1 genes polymorphisms Type II diabetes miletus patients in Basra Iraq International. Journal Current Microbiology Applied Science 3(11):288-299.

 

Amer MA (2011). Influence of glutathione S-transferase polymorphisms on type-2 diabetes mellitus risk. Genetics and Molecular Research 10(4):3722-3730.
Crossref

 

Bayness JW, Thorpe SR (1999). Role of oxidative stress in diabetic complications: a new perspective to an old paradigm. Diabetes 48(1):1-9.
Crossref

 

Bell DA (1993). Genetic risk and carcinogen exposure: a common inherited defect of the carcinogen-metabolism gene glutathione Stransferase M1 (GSTM1) that increases susceptibility to bladder cancer. Journal of the National Cancer Institute 85(14):1159-1164.
Crossref

 

Bid HK, Hayes KR, Saxena M (2010). Association of glutathione S- transferase (GSTMI, TI and PI) gene polymorphisms with type 2 diabetes mellitus in north Indian population. Journal of Postgraduate Medicine 3(56):176-181.
Crossref

 

Datta SK (2010). Association of glutathione S-transferase M1 and T1 gene polymorphism with oxidative stress in diabetic and nondiabetic chronic kidney disease. Ren Fail 32(10):1189-1195.
Crossref

 

Gallou G, Ruelland A, Legras B, Maugendre D, Allannic H, Cloarec L (1993). Plasma malondialdehyde in type 1 and type 2, diabetic patients. Clinica chimica acta 214(2):227-234.
Crossref

 

Giron MD, Saito RGY (1999). Modulation of hepatic and intestinal glutathione S-trdnsferases and other antioxidant enzymes by dietary lipids in streptozotocin diabetic rats. Chemosphere 38(13):3003-3013.
Crossref

 

Hayes JD, Pulford DJ (1995). The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. Critical Reviews in Biochemistry and Molecular Biology 30(6):445-600.
Crossref

 

Hori M (2007). Combined glutathione S-transferase T1 and M1 positive genotypes afford protection against type 2 diabetes in Japanese. Pharmacogenomics 8(10):1307-1314.
Crossref

 

London SJ (1995). Polymorphism of glutathione S-transferase M1 and lung cancer risk among African-Americans and Caucasians in Los Angeles County, California. Journal of the National Cancer Institute 87(16):1246-1253.
Crossref

 

Marchetti PLR, Del Guerra S, Bugliani M, D'Aleo V, Occhipinti M, Boggi U, Marselli L, Masini M (2009). Goals of treatment for type 2 diabetes: beta-cell preservation for glycemic control. Diabetics Care 32(2):178-183.
Crossref

 

Moasser E (2012). Study of the association between glutathione S- transferase (GSTM1, GSTT1, GSTP1) polymorphisms with type II diabetes mellitus in southern of Iran. Molecular Biology Reports 39(12):10187-10192.
Crossref

 

Moyassar AZ, Thanaa FM, Mona MKEl-D, Amira HM, Noha AAM (2015). Glutathione S-transferase M1, T1 and P1 gene polymorphisms and the risk of developing type 2 diabetes mellitus in Egyptian diabetic patients with and without diabetic vascular complications. Alexandria Journal of Medicine 51(1):73-82.
Crossref

 

Pinheiro DS (2013). Evaluation of glutathione S-transferase GSTM1 and GSTT1 deletion polymorphisms on type-2 diabetes mellitus risk. PLoS One 8(10):e76262.
Crossref

 

Powers AC (2005) Diabetes Mellitus. In: Kasper DL, Fauci AS, Longo DL, Braunwald E, Hauser SL Jameson JL, Eds, Harrison's Principles of Internal Medicine, 16th Edition, McGraw-Hill, New York pp. 2152-2180.

 

Ramprasath T (2011). Potential risk modifications of GSTT1, GSTM1 and GSTP1 (glutathione-S-transferases) variants and their association to CAD in patients with type-2 diabetes. Biochem Biophys Res Commun, 407(1):49-53.
Crossref

 

Raza S (2014). Association of Glutathione-S-Transferase (GSTM1 and GSTT1) and FTO Gene Polymorphisms with Type 2 Diabetes Mellitus Cases in Northern India. Balkan Journal of Medical Genetics 17(1):47-54.
Crossref

 

Robertson RP, Harmon J, Tran PO, Tanaka Y, Takahashi H (2003). Glucose toxicity in beta-cells: Type 2 diabetes, good radicals gone bad, and the glutathione connection. Diabetes 52(3):581-587.
Crossref

 

Wang G, Li Q (2006). Genetic polyrnorphisms of GSTII, GSTM1, and NQol genes and diabetes mellitus risk in Chinese population. Biochemical and Biophysical Research Communications 341(2):310-313.
Crossref

 

Wang G, Zhang L, Li Q (2006). Genetic polymorphisms of GSTT1, GSTM1, and NQO1 genes and diabetes mellitus risk in Chinese population. Biochemical and Biophysical Research Communications 341(2):310-313.
Crossref

 

Whalen R, Boyer TD (1998). Human glutathione S-transferases. Seminars in Liver Disease 18(4):345-358.
Crossref

 

Whiting DR, Guariguata L, Weil C, Shaw J (2011). IDF diabetes atlas: global estimates of the prevalence of diabetes for 2011 and 2030. Diabetes research and clinical practice 94(3):311-321.
Crossref