International Journal of
Medicine and Medical Sciences

  • Abbreviation: Int. J. Med. Med. Sci.
  • Language: English
  • ISSN: 2006-9723
  • DOI: 10.5897/IJMMS
  • Start Year: 2009
  • Published Articles: 531

IJMMS Articles

Serum malondialdehyde, glutathione and nitric oxide levels in patients infected with Entamoeba coli

May 2009

While Entamoeba histolytica is a major human pathogen, other species like Entamoeba coliare not known to be pathogenic. Thus, there have been studies investigating the possible pathogenic nature of E. coli. The aim of this study is to evaluate the serum levels of malondialdehyde (MDA), glutathione (GSH) and nitric oxide (NO) levels in E. coli-infected patients. The study was conducted between...

Author(s): Ulku Karaman, Tugba Raika Kiran, Cemil Colak, Meryem Iraz, Tuncay Celik and Aysun Bay Karabulut,

A faster and safer staining technique for acid fast bacilli in resource-poor setting

May 2009

The traditional Ziehl-Neelsen (ZN) method used for the staining of acid fast bacilli contains phenol and because of the hazardous nature and inherent danger of phenol, this study was carried out to develop a faster and safer method in our environment that will exclude toxic phenol from the staining solution. “Morning fresh”, a commercial liquid dish washing solution with super grease cutting power and citrus...

Author(s): Da’si Kemgni Raoul, Ogboi Sonny Johnbull and Idoko John

Pharmacogenomics: benefits of personalized medicines

April 2009

Pharmacogenomics is a science that examines the inherited variations in genes that dictate drug response and explores the ways these variations can be used to predict whether a patient will have a good, bad, or no response at all to a drug. It refers to the general study of all of the many different genes that determine drug behavior. It could also guide companies in designing clinical trials that would more...

Author(s): Avinash Puri

An unusual cause of acute tympanic membrane perforation: a case report

April 2009

This is a case report of a 26 – year old lady who presented in the Accident and Emergency Department of our hospital with complaints of sudden onset of right otalgia, tinnitus and loss of hearing which she claimed started at about 12:30 h after vigorous kissing incident. The tympanic membrane was ruptured. She was managed conservatively with oral antibiotics with spontaneous and complete healing of the perforated...

Author(s): Anelechi B. Chukuezi and Jones N. Nwosu

Methotrexate-induced toxic epidermal necrolysis: a case report

April 2009

Methotrexate (MTX) is a folic acid antagonist that inhibits the enzyme dihydrofolate reductase resulting in decreased cell levels of tetrahydrofolate. Adverse cutaneous reactions to MTX are usually dose-related and have been mainly reported in patients receiving extremely large doses of chemotherapy. Toxicity can affect multiple organ systems including bone marrow, liver, intestinal tract, kidneys, lungs, skin, and...

Author(s): I. Tazi, A. Madani, S. Zafad, M. Harif, A. Quessar and S. Benchekroun

Intraoperative low molecular weight heparin and postoperative bleeding

April 2009

A case of postoperative bleeding associated with low molecular weight heparin (LMWH) administration is reported. A literature search suggests that perioperative bleeding can be as high as 11% when LMWH is administered intraoperatively. When administered 6 h postoperatively, LMWH does not signi-ficantly increase the risk of bleeding whilst retaining efficacy for venous thromboembolism prop-hylaxis. Although LMWH has not...

Author(s): Michael K. F. Choo

Efficacy of some antibacterial agents on Staphylococcus aureus isolated from various burn cases

April 2009

The present study aimed to determine the major bacterial types from various burn cases and a study of antibacterial activity of plant extracts against Staphylococcus aureus isolated from burn cases in comparison with standard antibiotics.A total of 35 specimens were collected from burned patients (both sex, various degrees of burns) in burns unit of Al-Basrah General Hospital and Alsader Teaching...

Author(s): Ihsan Edan Alsaimary

The influence of mode of delivery on the levels of high-sensitivity C - reactive protein determined in umbilical cord blood

April 2009

Data suggest that the fetus responds to chronic hypoxia by higher umbilical cord blood high-sensitive CRP concentrations. In order to evaluate the effects of acute hypoxia on fetus, cord blood high-sensitive CRP concentrations according to the delivery mode were compared. High-sensitive CRP concentration was measured by an immunonephelometric method in umbilical cord blood samples from 45 newborns born by...

Author(s): AyÅŸem Kaya, Güner Karatekin, Işıl Uzunhasan and Sami HatıpoÄŸlu

Bone tumors at Addis Ababa University, Ethiopia: agreement between radiological and histopathological diagnoses, a -5-year analysis at Black-Lion Teaching Hospital

April 2009

The study aims at looking into clinical, radiological and histopathological agreement in diagnosing bone tumors and elaborates the spectrum of bone tumors referred to Black-Lion Hospital, BLH. All bone tumor patients, who presented to all the three departments at BLH between the study periods of December 2003 – March 2008 were recruited. the radiological and histopathological diagnoses made were categorized...

Author(s): Bayush E. Negash, Daniel Admasie, Biruk L. Wamisho and Mihiret W. Tinsay

Aminothienoandrostane: novel promising anti-tumor agent

April 2009

The sensitivity of liver to chemotherapy provides the basis of novel investigational treatment. An amino thienoandrostane derivative was synthesized and tested in vitro for anti-tumor activity against heapto-ma cell lines (HepG2) using MTT assay. Also the in vivo anti-tumor activity was evaluated against Ehrlich ascites carcinoma (EAC). After 24 h of tumor inoculation, the tested compound was...

Author(s): Gamal A. Elmegeed, Mohamed El-Far, Hanaa Mahrous and Mohamed A. Tantawy

Insulin resistance and blood pressure in Nigerian type 2 diabetic patients

April 2009

Considerable interest has been generated on the possible role of insulin resistance (IR) in the etiology and sustenance of hypertension among type-2 diabetic subjects. There is paucity of data on this relationship on African diabetic patients. The aim of this study is to show the relationship between homeostasis model assessment (HOMA) derived insulin resistance (IR) scores and blood pressure among type-2 diabetic...

Author(s): A. G. Bakari and G. C. Onyemelukwe

Anthropometric comparison of nasal indices between Andoni and Okrika tribes of Rivers State, Nigeria

April 2009

A comparative study on Nasal Index was carried out on subjects from Andoni and Okrika tribes of Rivers State in the Niger Delta region of Nigeria. Four hundred individuals were randomly selected from each tribe comprising 200 males and 200 females, respectively. The ages of the subjects ranged from 21-30 years. The height of the nose (NH) and the breadth of the nose (NB) were measured for each subject using a sliding...

Author(s): Oladipo, G. S., Eroje M. A. and Fahwehinmi H. B.

Performance of syphilis serology in students of Ambrose Alli University, Ekpoma, Nigeria

April 2009

5 ml of venous blood was aseptically collected from 112 consenting, apparently healthy students of Ambrose Alli University Ekpoma, Nigeria. The enrollees were 62 males and 50 females (age range, 15 – 44 years). The Rapid Plasma Reagin (RPR) and Immunochromatographic tests (Spodex Diagnostic Company) were used to screen and confirm the presence of syphilitic antibodies in their serum and plasma. Out of the 112...

Author(s): Eyaufe, A. A., Osagie, R. N., Isibor, J. O., Okwu, G. I., Oriakhi, R. E. and Turay, A. A.

Editorial: Chemists at Max Planck Institute (Germany) regenerate Artemisinin from its waste product

March 2009

Author(s): Dr. John  Ibekwe

Prostatic adenocarcinoma coexisting with schistosomiasis: A case report and review of literature

March 2009

Adenocarcinoma of the prostate is the commonest form of cancer in men and the second leading cause of cancer death.  Not much is known about the aetiology of prostatic cancer. We report a rare case of prostatic adenocarcinoma coexisting with schistosomiasis of the prostate, and review of literature. The association between schistosomiasis and cancer has been well documented in bladder cancer, implicating the...

Author(s): Agabus N. Manasseh, Godwins O. Echejoh, Matthew N. Tanko, Olugbenga O. Silas, Nuhu K. Dakum and Barnabas M. Mandong

Update to risk factors for hepatocellular carcinoma

March 2009

Hepatocellular carcinoma (HCC) became a prevalent disease in many populations worldwide. It initiates many economic problems in management modalities and leads to increasing mortality rates. Many trials are made all over the world to implement specific early markers for detection and prediction of the disease, hoping to set a more precise strategy for liver cancer prevention. Unfortunately, many economic, cultural and...

Author(s): Nabil Abdel-Hamid

Brief review of sarcoidosis of the thyroid gland

March 2009

Sarcoidosis of the thyroid gland is rare. It is rarely reported in the medical literature. In this review article we go over various presentation of sarcoidosis of the thyroid gland, ways to diagnose it, and treatment options. Key words: Sarcoidosis, thyroid gland, hypothyroidism, Graves' disease

Author(s): Talal Hussain Muzaffar, Jaber Mohammed Al-Ansari and Hassan Al-Humrani

Differential induction of LRP16 by liganded and unliganded estrogen receptor a in SKOV3 ovarian carcinoma cells

March 2009

Previously, we investigated the induction effect of LRP16 expression by estrogen (E2) and established a feed-forward mechanism that activated ERa transactivation in estrogen-dependent epithelial cancer cells. LRP16 is required for ERa signaling transduction by functioning as an ERa coactivator. In this study, we demonstrated that LRP16 expression was up-regulated in E2-responsive BG-1 ovarian cancer...

Author(s): Liyuan Tian, Zhiqiang Wu, Yali Zhao, Yuanguang. Meng, Yiling Si, Xiaobing Fu,             Yiming Mu and W-D Han

In situ distribution of hepatitis C virus (HCV) RNA in the liver: Relationship to histopathology and serum HCV-RNA levels

March 2009

In situ hybridization (ISH) technique was applied to 60 liver biopsies obtained from Egyptian patients with chronic HCV hepatitis in an attempt to: assess the tissue localization of HCV RNA in the liver and to investigate its relationship to the liver pathology, serum level of alanine transaminase (ALT) and viral load in the serum. No similar studies have been reported from Egypt, which is an area of high HCV...

Author(s): Thanaa El-Sayed Helal, Mahmoud Ismail Hassan, Munir Ali El-Ganzuri, Ahmed Mostafa Ahmed and Sahar Ezzelarab

Hepatoprotective and some haematological effects of Allium sativum and vitamin C in lead-exposed Wistar rats

March 2009

The hepatoprotective and some haematological effects of Allium sativum (Garlic) and vitamin C were studied on experimental rats that were exposed to lead (Pb) for one week. Twenty – four female Wistar rats were divided into four groups of six rats per group. Rats in group A were kept as the control. Rats in groups B, C and D were exposed to 100 µmol/kg body weight of lead acetate intraperitoneally...

Author(s): G. O. Ajayi,  T. T. Adeniyi and D. O. Babayemi

Multi-drug resistant Staphylococcus aureus in clinical cases in Ile-Ife, Southwest Nigeria

March 2009

  A study to investigate the susceptibility pattern of Staphylococcus aureus to conventional antibiotics being frequently prescribed in Ile-Ife, South Western Nigeria was carried out. One hundred and seven samples from various clinical samples were collected from Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria. The isolates of S. aureuswere characterized and identified...

Author(s): Adegoke, Anthony Ayodeji and Komolafe, Amos Omoniyi

Serum total cholesterol in hypertensive Northern Nigerians

March 2009

  Hypertension is associated with several lipid abnormalities including elevated total cholesterol (TC) concentrations. The presence of dyslipidaemia increases risks of cardiovascular morbidity and mortality. There is paucity of data on the pattern of serum TC in hypertensive patients in northern Nigeria. The objective of the present study was therefore to evaluate serum total cholesterol in hypertensive...

Author(s): Akuyam S. A., Aghogho U. B., Aliyu I. S.and Bakari A. G.

Antibiotic susceptibility and plasmid pattern of Pseudomonas aeruginosa from the surgical unit of a university teaching hospital in north central Nigeria

March 2009

This study determined the susceptibility pattern and multiple antibiotic resistance (MAR) index of 92 Pseudomonas aeruginosa strains from clinical samples comprising mainly urine (51.1%) and wounds (41.3%) obtained from the surgical units of Ahmadu Bello University Teaching Hospital, Zaria, Nigeria; over a 24-month period. The strains were susceptible to imipenem (94.6%), ciprofloxacin (90.2%), amikacin...

Author(s): A. T. Olayinka, B. O. Olayinka and B. A. Onile

Hepatocellular carcinoma: Risk factors, pattern of presentation and outcome in a tertiary health facility

March 2009

Hepatocellular carcinoma is the fifth most common cancer in the world. Its incidence is increasing worldwide ranging between 3 and 9% annually.  The aim of this study was to see the pattern of clinical presentation, identify the possible risk factors and the clinical outcome among HCC patients presenting at our health facility. The case records of all patients with histopathological diagnosis of HCC within the...

Author(s): Akande Oladimeji Ajayi, Ebenezer Adekunle Ajayi and Oluwole Akinwumi Komolafe

Effect of metformin and folic acid on plasma homocysteine level in type 2 diabetic patients

March 2009

Hyperhomocysteinemia is associated with an increased risk of cardiovascular disease in diabetic patients. The aim of this study was to evaluate effects of metformin and folic acid on plasma homocysteine level in diabetic patients. In this clinical trial 47 new cases of type 2 diabetes were randomized to two groups. We treated patients in trial group with metformin and 1 mg folic acid, whereas patients in control group...

Author(s): Mohammad Mohammadi, Masoud Amini, Ashraf Aminiorroay, Hasan Rezvanian, Ali Kachuei, Mansour Siyavash, Soodabeh- Rahimi Saghandand Mohammad Afkhami-Ardekani

Granulomatous inflammation in lymph nodes draining cancer: A coincidence or a significant association!

February 2009

Granulomatous inflammation is considered to be an immune mechanism against infections or certain non-neoplastic conditions. Rarely granuloma formation may be noted in neoplastic disorders also. However a granulomatous response in the lymph nodes draining cancers is unusual. Such granulomas may sometimes show tumour cells in their centre. The exact cause of this phenomenon is not known but an immunologic reaction to...

Author(s): Alka Bhatia, Yashwant kumar and Anjali Solanki Kathpalia

Bacteriology of automobile accident wounds infection

February 2009

Purulent materials were collected aseptically with the aid of sterile swab sticks from Forty (40) patients with automobile accident wounds at University of Uyo Teaching Hospital (UUTH) and James Accident and Bone Victim Hospital (JABH) in Uyo. These samples were examined microbiologically for the presence of aerobic bacteria and the susceptibility of these organisms to different conventional antibiotics was assessed...

Author(s): Akinjogunla, O. J., Adegoke, A. A., Mboto, C. I., Chukwudebelu, I. C. and Udokang, I. P.

Isolation and characterization of a new chalcone from the leaves of Heteropyxis natalensis

February 2009

Chromatographic analysis of the defatted dichloromethane extract of the leaves ofHeteropyxis natalensis afforded the isolation of (E)-1-(2’,4’-dihydroxy, 5’-methoxy, 3’-methylphenyl)-3-phenylprop-2-en-1-one (R1 = Me; R2 = OH; R3 = OMe; R4 = H) a  chalcone. The structure of this compound was established by its spectroscopic data-1D, 2D-NMR, EIMS and HR-EIMS. Key...

Author(s): Adesanwo, J. K., Shode, F. O., Aiyelaagbe, O., Oyede, R. T. and Baijnath, H.

Biofeedback application for somatoform disorders and attention deficit hyperactivity disorder (ADHD) in children

February 2009

Biofeedback is a modern computer-related technique used mainly for assessment and therapy of psychophysiological disorders. The influx of about 800 patients per year with stress related disorders is the cause of extensive clinical use of biofeedback in our Department. In this article some results obtained with electrodermal (EDR) and electroencephalography (EEG) biofeedback in the assessment and therapy of children with...

Author(s): Nada Pop-Jordanova

Diagnostic modeling with differences in plasma amino acid profiles between non-cachectic colorectal/breast cancer patients and healthy individuals

January 2009

Metabolic changes in patients with cancer lead to alterations in their amino-acid balances. Thus, amino-acid profiles may be useful as biomarkers of cancers. This study was conducted to analyze amino-acid profiles in plasma by multivariate analysis, in order to elucidate differences between cancer patients and controls. Venous blood samples were taken from colorectal and breast cancer patients, and healthy controls....

Author(s): Naoyuki Okamoto, Yohei Miyagi, Akihiko Chiba, Makoto Akaike, Manabu Shiozawa, Akira Imaizumi, Hiroshi Yamamoto, Toshihiko Ando, Minoru Yamakado and Osamu Tochikubo

Association of angiotensin converting enzyme gene I/D polymorphism with vitiligo in South Indian population

January 2009

Vitiligo or leukoderma is a chronic skin condition that causes loss of pigment due to destruction of melanocytes, resulting in irregular pale patches of skin. Vitiligo is polygenic disease and associated with autoimmunity. Angiotensin converting enzyme (ACE) is capable of modulating cutaneous neurogenic inflammation. An insertion/deletion (I/D) polymorphism of a 287-base pair repetitive sequence in intron 16 of the ACE...

Author(s): Farha Deeba⊃, Kaiser Jamil⊃, Syed Rabbani⊃, M.A.Waheed⊃ and Hanmanth Rao⊃

Page 11 of 11, showing 31 records out of 531 total, starting on record 501, ending on 531