African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12487

Review

Ellagic acid: Biological properties and biotechnological development for production processes

Leonardo Sepúlveda1, Alberto Ascacio1, Raúl Rodríguez-Herrera1, AntonioAguilera-Carbó2 and Cristóbal N. Aguilar1*
1Department of Food Science and Technology, Universidad Autónoma de Coahuila, Saltillo, Coahuila, México. 2Department of Food Science and Nutrition, Universidad Autónoma Agraria Antonio Narro, Buenavista, Saltillo, Coahuila, México.
Email: [email protected]

  •  Accepted: 15 April 2011
  •  Published: 30 May 2011

Abstract

Ellagic acid, 2,3,7,8-tetrahydroxy-chromeno[5,4,3-cde]chromene-5,10-dione, is a powerful bioactive compound with many potential pharmacological and industrial applications. In this review, the chemical aspects, biological properties and diverse potential applications of ellagic acid for different industries were described. This review also discussed the advance in ellagitannin biodegradation, focusing on the process of isolation of microorganisms and strain selection, medium and culture optimization, as well as fermentation systems for commercially viable industrial scale production. The performances of various fermentation techniques that have been applied for the production of ellagic acid from residual by-products werecompared, while the advantages and disadvantages of each plant source were also discussed.

 

Key words: Ellagic acid, ellagitannin, biodegradation, fungal physiology, solid-state fermentation, submerged fermentation.