African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12487

Review

X-Chromosome short tandem repeat, advantages and typing technology review

Imad Hadi Hameed*
  • Imad Hadi Hameed*
  • Department of Molecular Biology, Babylon University, Hilla City, Iraq.
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Muhanned Abdulhasan Kareem
  • Muhanned Abdulhasan Kareem
  • Babylon University, Centre of Environmental Research, Iraq.
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Rafid H.H
  • Rafid H.H
  • Ministry of Health of Iraq, Iraq.
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  •  Received: 20 August 2014
  •  Accepted: 22 September 2014
  •  Published: 18 February 2015

Abstract

 

Microsatellites of the X-chromosome have been increasingly studied in recent years as a useful tool in forensic analysis. This review describes some details of X-chromosomal short tandem repeat (STR) analysis. Among them are: microsatellites, amplification using polymerase chain reaction (PCR) of STRs, PCR product evaluation, PCR product purification, separation and detection, data analysis of STR by Identity Software, locus information and allele frequencies for X-chromosomal STR in different populations (DXS101, DXS7423, DXS8377, DXS6789, DXS6807 genetic loci) and advantages of X-chromosomal micro-satellites. In forensic casework and DNA databases, polymorphism in STR is important as a forensic genetic marker.

 

Key words: Short tandem repeat (STR) loci, forensic, interpretation.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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