African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12481

Full Length Research Paper

Study of malondialdehyde (MDA) content, superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activities in chickens infected with avian infectious bronchitis virus

Hai-feng Wang1,2, Xiu-hui Zhong1,3*, Wan-yu Shi1 and Bing Guo2
1College of Animal Science and Technology, Agricultural University of Hebei, Baoding, 071001, China. 2College of Animal Science and Technology, Hebei North University, Zhangjiakou, 075000, China. 3Institute of Traditional Chinese Veterinary Medicine, Agricultural University of Hebei, China
Email: [email protected] or [email protected]

  •  Accepted: 10 June 2011
  •  Published: 17 August 2011

Abstract

This study was carried out to investigate the changes of serum oxidative index in chickens infected with avian infectious bronchitis virus. Eighty (80) 15-day-oldchickens were divided into two groups randomly: the control group and the experimental group. Birds in the experimental group were inoculated with infectious bronchitis virus, then the superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activities and malondialdehyde (MDA) contents in the serum were detected in each group at days 1, 3, 6, 9, 12 post infection, respectively. Results showed that SOD and GSH-Px activities in the serum of the experiment group decreased after infection (P<0.05 or P<0.01). MDA contents of the experiment group increased after infection, and was significantly higher than those of the control group at days 6 and 9 post infection (P<0.01). The results implied that oxidative damage may regulate the occurrence and development of avian infectious bronchitis.

 

Key words: Avian infectious bronchitis, superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), malondialdehyde (MDA).

Abbreviation

MDA, Malondialdehyde; SOD, superoxide dimutase; GSH-Px,glutathione peroxidase; FR, free radical; IB, infectious bronchitis; IBV, infectious bronchitis virus.

Copyright © 2024 Author(s) retain the copyright of this article.

This article is published under the terms of the Creative Commons Attribution License 4.0

Back to Vol. 10 No. 45
Back to articles
  • Articles on Google by:
SUBSCRIBE TO RSS
SUBMIT MANUSCRIPT
CONFERENCES