African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12427

Full Length Research Paper

Analgesic and anti-inflammatory activities of propolis obtained from Gboko, Nigeria

IPAV Selumun Solomon
  • IPAV Selumun Solomon
  • Department of Chemical Sciences, University of Mkar, Mkar, Benue State, Nigeria.
  • Google Scholar
IGOLI John Ogbaji
  • IGOLI John Ogbaji
  • Department of Chemistry, Federal University of Agriculture, Makurdi, Benue State, Nigeria.
  • Google Scholar
TOR-ANYIIN Terrumun Amom
  • TOR-ANYIIN Terrumun Amom
  • Department of Chemistry, Federal University of Agriculture, Makurdi, Benue State, Nigeria.
  • Google Scholar
ANYAM John Vershima
  • ANYAM John Vershima
  • Department of Chemistry, Federal University of Agriculture, Makurdi, Benue State, Nigeria.
  • Google Scholar


  •  Received: 07 February 2022
  •  Accepted: 21 June 2022
  •  Published: 31 July 2022

References

Abdel Mahdi Kassim Altaee R (2014). Evaluation the Analgesic and Anti-inflammatory Activity of Aqueous Extracts of Iraqi Propolis in Male Albino Mice. Journal of Kerbala University 12(2):1-6.

 

Abozid MM, Ahmed AA (2013). Chemical Composition of Egyptian and Commercial Propolis and its Effects on Liver function and Lipid Profiles in Albino Rats. Journal of Biological, Chemical and Environmental Sciences 8(2):323-340.

 

Adzu B, Amos S, Wambebe C, Gamaniel K (2001). Antinociceptive Activity of Zizyphusspina-christi Root Bark Extract. Fitoterapia 72(4):344-350.
Crossref

 

Akah P, Nwabie AI (1994). Evaluation of Nigerian traditional medicines: Plants used for rheumatic disorder. Journal of Ethnopharmacology 42(3):179-182.
Crossref

 

Alencar SM, Oldoni TLC, Castro ML, Cabral ISR, Costa-Neto CM, Cury JA, Rosalen PL, Ikegaki M (2007). Chemical composition and biological activity of a new type of Brazilian propolis: red propolis. Journal of Ethnopharmacology 113(2):278-283.
Crossref

 

Al-Hariri MT, Abualait TS (2020). Effects of Green Brazilian Propolis Alcohol Extract on Nociceptive Pain Models in Rats. Plants 9(1102):1-9.
Crossref

 

Amresh G, Reddy GD, Rao Ch V, Singh PN (2007). Evaluation of anti-inflammatory activity of Cissampelos pareira root in rats. Journal of Ethnopharmacology 110(3):526-531.
Crossref

 

Arvouet-Grand A, Lejeune B, Bastide P, Pourrat A, Privat AM, Legret P (1993). Propolis Extract. I. Acute Toxicity and Determination of Acute Primary Cutaneous Irritation Index. Journal de Pharmacie de Belgique 48(3):165-170.

 

Atta A, Alkofahi A (1998). Anti-nociceptive and Anti-inflammatory Effects of some Jordanian Medicinal Plant Extracts. Journal of Ethnopharmacology 60(2):117-124.
Crossref

 

Babatunde IR, Abdulbasit A, Oladayo MI, Olasile OI, Olamide FR, Gbolahan BW (2015). Hepatoprotective and Pancreatoprotective Properties of the Ethanolic Extract of Nigerian Propolis. Journal of Intercultural Ethnopharmacology 4(2):102-108.
Crossref

 

Bankova V (2005). Recent Trends and Important Developments in Propolis Research. Evidence-Based Complementary and Alternative Medicine 2(1):29-32.
Crossref

 

Bankova V, Castro SLD, Marcucci MC (2000). Propolis: recent advances in chemistry and plant origin. Apidologie 31:3-15.
Crossref

 

Batista LLV, Campesatto EA, Assis MLB, Barbosa APF, Grillo LAM, Dornelas CB (2012). Comparative study of topical green and red propolis in the repair of wounds induced in rats. Revista do Colegio Brasileiro de Cirurgioes 39(6):515-520.
Crossref

 

Bispo-Junior W, Miranda EO, Alvino V, Araujo B, Silva DW, Porfirio Z (2012). Antimicrobial activity of fractions of red propolis from Alagoas, Brazil. Semina: Ciências Biológicas e da Saúde Londrina 33(1):3-10.
Crossref

 

Boisard S, Le Ray AM, Landreau A, Kempf M, Cassisa V, Flurin C, Richomme P (2015). Antifungal and Antibacterial Metabolites from a French Poplar type Propolis. Evidence Based Complementary and Alternative Medicine 10 p.
Crossref

 

Bonvehi JS, Coll FV, Jorda R (1994). The Composition, Active Components and Bacteriostatic Activity of Propolis in Dietetics. Journal of the American Oil Chemists' Society 71(5):529-532.
Crossref

 

Brodowska KM (2017). Natural flavonoids: Classification, Potential Role and Application of Flavonoid Analogues. European Journal of Biological Research 7(2):108-123.

 

Bueno-Silva B, Franchin M, Alves CDF, Denny C, Colón DF, Cunha TM, Alencar SM, Napimoga MH, Rosalen PL (2016). Main pathways of action of Brazilian red propolis on the modulation of neutrophils migration in the inflammatory process. Phytomedicine 23(13):1583-1590.
Crossref

 

Bankova V (2005). Chemical Diversity of Propolis and the Problem of Standardization. Journal of Ethnopharmacology 100(1-2):114-117.
Crossref

 

Bankova VS, Christov R, Kujumgiev A, Marcucci MC, Popov S (1995). Chemical Composition and Antibactericidal Activity of Brazilian Propolis. Zeitschrift für Naturforschung C 50(3-4):167-172.
Crossref

 

Castaldo S, Capasso F (2002). Propolis, an old remedy used in modern medicine. Fitoterapia 73(1):1-6.
Crossref

 

Cavendish RL, de Souza Santos J, Neto RB, Paixão AO, Oliveira JV, de Araujo ED, e Silva AAB, Thomazzi SM, Cardoso JC, Gomes MZ (2015). Antinociceptive and Anti-inflammatory Effects of Brazilian Red Propolis Extract and Formononetin in Rodents. Journal of Ethnopharmacology 173:127-133.
Crossref

 

Chen C, Shen A (2008). Synergistic Antifungal Activities of Thymol Analogues with Propolis. Natural Product Communications 3(2):279-282.
Crossref

 

Christov R, Trusheva B, Popova M, Bankov V (2005). Chemical composition of propolis from Canada, its antiradical activity and plant origin. Natural Product Research 19(7):673-678.
Crossref

 

De Castro SL (2001). Propolis, Biological and Pharmacological activities. Therapeutic uses of this Bee-Product. Annual Review of Biomedical Sciences 3:49-83.
Crossref

 

Devequi-Nunes D, Machado BAS, Barreto GA, Rebouças Silva J, da Silva DF, da Rocha JLC, Brandão HN, Borges VM, Umsza-Guez MA (2018). Chemical Characterization and Biological Activity of Six different Extracts of Propolis through Conventional Methods and Supercritical Extraction. PLoS ONE 13(12):1-20.
Crossref

 

Dobrowolski JW, Vohora SB, Sharma K, Shah SA, Naqvi SAH, Dandiya PC (1991). Antibacterial, Antifungal, Antiamoebic, Antiinflammatory and Antipyretic Studies on Propolis Bee Products. Journal of Ethnopharmacology 35(1):77-82.
Crossref

 

El-Masry TA, Emara AM, El-Shitany NA (2011). Possible Protective Effect of Propolis against Lead-Induced Neurotoxicity in Animal Model. Journal of Evolutionary Biology Research 3(1):4-11.

 

Fazio A, Plastina P, Meijerink J, Witkamp RF, Gabriele B (2013). Comparative Analyses of Seeds of Wild Fruits of Rubus and Sambucus species from Southern Italy: Fatty Acid Composition of the Oil, Total Phenolic Content, Antioxidant and Anti-inflammatory Properties of the Methanolic Extracts. Food Chemistry 140(4):817-824.
Crossref

 

Fernandez MA, Saenz MT, Garcia MD (1998). Anti-inflammatory Activity in Rats and Mice of Phenolic Acids Isolated from Scrophularia frutescens. Journal of Pharmacy and Pharmacology 50(10):1183-1186.
Crossref

 

Frozza COS, Garcia CSC, Gambato G, Souza MDO, Salvador M, Moura S, Padilha FF, Seixas FK, Collares T, Borsuk S, Dellagostin OA, Henriques JA, Roesch-Ely M (2013). Chemical characterization, antioxidant and cytotoxic activities of Brazilian red propolis. Food and Chemical Toxicology 52:137-142.
Crossref

 

Górniak I, Bartoszewski R, Króliczewski J (2019). Comprehensive Review of Antimicrobial Activities of Plant Flavonoids. Phytochemistry Review 18(1):241-272.
Crossref

 

Greenaway W, May J, Scaysbrook T, Whatley FR (1999). Identification by gas chromatography-mass spectrometry of 150 compounds in propolis. Zeitschrift für Naturforschung C 46(1-2):111-121.
Crossref

 

Havsteen B (1983). Flavonoids, a Class of Natural Products of High Pharmacological Potency. Biochemical Pharmacology 32(7):1141-1148.
Crossref

 

Ichikawa H, Satoh K, Tobe T, Yasuda I, Ushio F, Matsumoto K, Endo K, Ookubo C (2002). Free Radical Scavenging Activity of Propolis. Redox Report 7(5):347-350.
Crossref

 

Inui S, Hatano A, Yoshino M, Hosoya T, Shimamura Y, Masuda S, Ahn MR, Tazawa S, Araki Y, Kumazawa S (2014). Identification of the Phenolic Compounds Contributing to Antibacterial Activity in Ethanol Extracts of Brazilian Red Propolis. Natural Product Research 28(16):1293-1296.
Crossref

 

Ipav SS, Moronkola DO, Aiyelaagbe OO (2018). Analgesic Activities of Leaf, Stem and Root Essential Oils of Corchorus olitorius L. (Tiliaceae) from Nigeria. Journal of Applied Biosciences 123:12388-12395.

 

Khalil ML (2006). Biological activity of bee propolis in health and disease. Asian Pacific Journal of Cancer Prevention 7(1):22-31.

 

Li F, Awale S, Tezuka Y, Kadota S (2008). Cytotoxic constituents from Brazilian red propolis and their Structure-Activity Relationship. Bioorganic & Medicinal Chemistry 16(10):5434-5440.
Crossref

 

Li YC, Xian YF, Ip SP, Su ZR, Su JY, He JJ, Xie QF, Lai XP, Lin ZX (2011). Anti-inflammatory Activity of Patchouli Alcohol Isolated from Pogostemonis herba in Animal Models. Fitoterapia 82(8):1295-1301.
Crossref

 

Marcucci MC, DeCamargo FA, Lopes CMA (1996). Identification of amino acids in Brazilian propolis. Zeitschrift für Naturforschung C 51(1-2):11-14.
Crossref

 

Mirazi N, Hosseini A (2013). Evaluation of Antinociceptive Activity of Berberis Vulgaris L. Fruit's Hydroethanolic Extract in Male Mice. Iranian Journal of Pharmaceutical Sciences 9(4):15-22.

 

Mountassir M, Chaib S, Selami Y, Khalki H, Ouachrif A, Moubtakir S, Aboufatima R, Zyad A, Benharref A, Chait A (2014). Antinociceptive Activity and Acute Toxicity of Moroccan Black Propolis. International Journal of Engineering Research and Technology 3(2):2393-2397.

 

Murugan R, Parimelazhagan T (2013). Study of Anti-nociceptive, Anti-inflammatory Properties and Phytochemical Profiles of Osbeckia parvifolia Arn. (Melastomataceae). Industrial Crops and Products 51:360-369.
Crossref

 

Nande WU, Igoli JO (2017). Isolation and Characterisation of bioactive compounds from plant materials: The Nigerian situation. Nigerian Journal of Pure and Applied Sciences 9(1):132-143.

 

Parandin R, DaroogariS (2019). Anti-Inflammatory and Antinociceptive Activities of the Ethanolic Extract of Propolis in Male Mice and Rats. Zahedan Journal of Research in Medical Sciences 21(2):1-7.
Crossref

 

Paulino N, Dantas AP, Bankova V, Longhi DT, Solange AS, de Castro L, Calixto JB (2003). Bulgarian Propolis Induces Analgesic and Anti-inflammatory Effects in Mice and Inhibits In Vitro Contraction of Airway Smooth Muscle. Journal of Pharmacological Sciences 93(3):307-313.
Crossref

 

Pimenta HC, Violante IM, Musis CR, Borges ÁH, Aranha AM (2015). In vitro Effectiveness of Brazilian Brown Propolis against Enterococcus faecalis. Brazilian Oral Research 29(1):1-6.
Crossref

 

Razmi A, Zarghi A, Arfaee S, Naderi N, Faizi M (2013). Evaluation of Anti-nociceptive and Anti-inflammatory Activities of Novel Chalcone Derivatives. Iranian Journal of Pharmaceutical Research 12:153-159.

 

Ristivojevi? P, Trifkovi?b J, Andri? F, Milojkovi?-Opsenicab D (2015). Poplar-type Propolis: Chemical Composition, Botanical Origin and Biological Activity. Natural Product Communications 10(11):1869-1876.
Crossref

 

Santos FA, Rao VSN, Silveira ER (1998). Investigations on the antinociceptive effect of Psidium guajava leaf essential oil and its major constituents. Phytotherapy Research 12(1):24-27.
Crossref

 

Seidel V, Peyfoon E, Watson DG, Fearnley J (2008). Comparative Study of the Antibacterial Activity of Propolis from Different Geographical and Climatic Zones. Phytotherapy Research 22(9):1256-1263.
Crossref

 

Sforcin JM (2016). Biological Properties and Therapeutic Applications of Propolis. Phytotherapy Research 30(6):894-905.
Crossref

 

Sun L, Liao L, Wang B (2018). Potential Antinociceptive Effects of Chinese Propolis and Identification on Its Active Compounds. Journal of Immunology Research Article ID 5429543 6 p.
Crossref

 

Teixeira EW, Message D, Negri G, Salatino A, Stringheta PC (2008). Seasonal variation, chemical composition and antioxidant activity of Brazilian propolis samples. Evidence Based Complementary and Alternative Medicine 7(3):307-315.
Crossref

 

Tor-Anyiin TA, Igoli JO, Anyam JV, Anyam JN (2015). Isolation and antimicrobial activity of sarracenin from root bark of Strychnos spinosa. Journal of Chemical Society of Nigeria 40(1):71-75.

 

Uwaya DO, Okakwu R, Omozuwa OP (2020). In-Vivo and In-Vitro Anti-Inflammatory Activities of the Aqueous Extract of Di Herbal Formulation (Euphorbia hirta and lactuca virosa). Journal of Applied Sciences and Environmental Management 24(11):1979-1985
Crossref

 

Vardar-Ünlü G, Silici S, Ünlü M (2008). Composition and In vitro Antimicrobial Activity of Populus Buds and Poplar-type Propolis. World Journal of Microbiology and Biotechnology 24(7):1011-1017.
Crossref

 

Wang Y, Chen P, Tang C, Wang Y, Li Y, Zhang H (2014). Antinociceptive and Anti-inflammatory Activities of Extract and Two Isolated Flavonoids of Carthamus tinctorius L. Journal of Ethnopharmacology 151(2):944-950.
Crossref

 

Wieczynska A, Wezgowiec J, Wieckiewicz W, Czarny A, Kulbacka J, Nowakowska D, Gancarz R, Wilk KA (2017). Antimicrobial Activity, Cytotoxicity and Total Phenolic Content of Different Extracts of Propolis from the West Pomeranian Region in Poland. Acta Poloniae Pharmaceutica 74(2):715-722.

 

Xu Y, Lin D, Yu X, Xie X, Wang L, Lian L, Fei N, Chen J, Zhu N, Wang G, Huang X, Pan J (2016). The Antinociceptive Effects of Ferulic Acid on Neuropathic Pain: Involvement of Descending Monoaminergic System and Opioid Receptors. Oncotarget 7(15):20455-20468.
Crossref

 

Xu Q, Wang Y, Guo S, Shen Z,Wang Y, Yang L (2014). Anti-inflammatory and Analgesic Activity of Aqueous Extract of Flospopuli. Journal of Ethnopharmacology 152(3):540-545.
Crossref

 

Yamanishi R, Yoshigai E, Okuyama T, Mori M, Murase H, Machida T, Okumura T, Nishizawa M (2014). The Antiinflammatory Effects of Flavanol-Rich Lychee Fruit Extract in Rat Hepatocytes. PLoS One 9(4):e93818.
Crossref

 

Yonathan M, Asres K, Assefa A, Bucar F (2006). In vivo Anti-inflammatory and Anti nociceptive Activities of Cheilanthes farinosa. Journal of Ethnopharmacology 108(3):462-470.
Crossref

 

Zhang Y, Shu Z, Yin L, Ma L, Wang X, Fu X (2015). Anti-inflammatory and Antinociceptive Activities of Non-Alkaloids Fractions from Aconitum flavum in vivo. Revista Brasileira de Farmacognosia 25(1):47-52.
Crossref

 

Zhao Y, Liu J, Liu C, Zeng X, Li X, Zhao J (2016). Anti-Inflammatory Effects of p-coumaric Acid in LPS Stimulated RAW264.7 Cells: Involvement of NF-kB and MAPKs Pathways. Medicinal Chemistry 6(5):327-330.
Crossref