African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12486

Full Length Research Paper

Effects of 2-chlorophenol and 2,4-dichlorophenol on mitotic chromosomes and nucleic acid content using Allium cepa and Vicia faba assays

AL-AHMADI MONA SAUD
  • AL-AHMADI MONA SAUD
  • Department of Biology, College of Science, University of Imam Abdulrahman Bin Faisal, P. O. Box 1982, Dammam 31441, Kingdom of Saudi Arabia.
  • Google Scholar


  •  Received: 27 December 2021
  •  Accepted: 20 June 2022
  •  Published: 30 September 2022

References

Abhilash PC, N Singh (2008). Distribution of hexachlorocyclohexane isomers in soil samples from a small-scale industrial area of Lucknow, north India, associated with Indian production. Chemosphere 73(6):1011-1015.
Crossref

 

Adeola AO (2018). Fate and toxicity of chlorinated phenols of environmental implications: A review. Medicinal and Analytical Chemistry International Journal 2(4):1-8.
Crossref

 

Ajay KJ, Sarbhoy RK (1988). Cytogenetic studies on the effects of some chlorinated pesticides III. Concluding remarks. Cytologia 53(3):427-436.
Crossref

 

Arzt ES, Castelo SF, Diaz A, Finkielman S, Nahmod VE (1989). The muscarinic pilocarpine inhibits DNA and interferon- γ cells. synthesis in peripheral blood mononuclear. International Journal of Immunopharmacology 11(3):275-281.
Crossref

 

Atuany A, El; Onuoha T (2018). Level of Organochlorine Pesticide Residues in selected Consumable Vegetables commonly sold im Benin City Markets. Journal of Applied Sciences and Environmental Management 22(10)1625-1630.
Crossref

 

Balcke GU, Wagener S, Kiesel BM, Benndorf M, SchlÖmann, Vogt C (2008). Kinetics of chlorobenzene biodegradation under reduced oxygen level. Biodegradation 19(4):507-518.
Crossref

 

Benfeito S, Tiago S, Garrido J, Andrade PB, Sottomayor MJ, Broges F, Garrido EM (2014). Effects of Chlorophenoxy Herbicide and Their Main Transformation Products on DNA Damage and Acetylcholinesterase Activity. BioMed Research Intranational.
Crossref

 

Brinkley BR, Tousson A, Valdivia M (1985). The kinetochore of mammalian chromosomes: structure and function in normal mitosis and aneuploidy, in: V.L. Dellarco, P.E. Votek and A. Hollaender (Eds), Aneuploidy, Etiology and Mechanisms, Plenum, New York, 243-265.
Crossref

 

Bukowska B (2006). Toxicity of 2,4-Dichlorophenenoxyacetic acid- Molecular Mechanisms. Polish Journal of Environmental Studies 15(3):365-374.

 

Campbell RD (1983). Mitotic Index. In: Lenhoff H.M. (eds) Hydra: Research Methods. Springer, Boston, MA.
Crossref

 

Chandra BR, Saharan RP, Sareen P K (2002). Clastogenic effect of trifluralin in Vici faba. Journal of Cytology and Genetics 3:201-203.

 

Chen J, Jiang J, Zhang F, Yu H, Zhang J(2004). Cytotoxic environmentally relevant chlorophenols on 1929 cells and their mechanisms. Cell Biology and Toxicology 20(3):183-196.
Crossref

 

Czaplicka M (2004). Sources and transformation of chlorophenols in the natural environment. Science of the Total Environment 322(1-3):21-39.
Crossref

 

Dimitris V, Antonopoulou M, Konstantioou KI (2016). Evaluation of toxicity and genotoxicity of 2-chlorophenol on bacteria, fish and human cells. The Science of total Environment 551-552 (1):649-566.
Crossref

 

Dimitrov BD, Gadeva PG (2006). Comparative genotoxicity of the herbicides Roundup, Stomp, and Reglone in plant and mammalian test system. Mutagenesis 21(6):375-382.
Crossref

 

Duchnowicz P, Koter M, Duda W (2002). Damage of erythrocyte by phenoxyacetic herbicides and their metabolites. Pesticide Biochemistry and Physiology 74(1):1-7
Crossref

 

El-Ghamery AA, El-Nahas AI, Mansour MM (2000). The action of atrazine herbicides as an indicator of cell division on chromosomes and nucleic acids content in root meristem of Allium cepa and Vicia faba. Cytologia 65(3):277-287.
Crossref

 

El-Hadary MH, Chung G (2013). Herbicides - A Double Edged Sword. Licensee Intech. Open. This chapter is distributed under the terms of the Creative Commons Attribution 3.0 License.

 

Fernandes TCC, Mazzeo DEC, Marin-Morales MA (2007). Mechanism of micronuclei formation in polyploidizated cells of Allium cepa exposed to trifluralin herbicide. Pesticide Biochemistry and Physiology 88(3):252-259.
Crossref

 

Lone IN, Shukla MS, Charles Richard JL, Peshev ZY, Dimitrov S, Angelov D (2013). Binding of NF-κ B to nucleosomes: effect of translational positioning, nucleosome remodeling and linker histone H1. PLoS Genetics 9(9):e1003830.
Crossref

 

Ganem NJ, Godinho SA, Pellman D(2009). A mechanism linking extra centrosomes to chromosomal instability. Nature 460(7252):278-282.
Crossref

 

Gaulden ME (1987). Hypothesis: Some mutagens directly alter specific chromosomal proteins (DNA topoisomerase II and peripheral proteins) to produce chromosomes stickiness, which causes chromosome aberrations. Mutagenesis 2(5):357-365.
Crossref

 

Hansch C, McCarns S, Smith C, Dodittle D (2000). Comparative QSAR evidence for a free-radical mechanism of phenol-induced toxicity. Chemico-Biological Interactions 127(1):61-72.
Crossref

 

Hidalgo A, Gonzalez-Reyes JA, Navas P, Garcia-Herduge G (1985). Abnormal mitosis and growth inhibition in Allium cepa root induced by Propham and chlorpropham. Cytobios 57(228):7-14.

 

Hoseiny-Rad M, Aivazi A (2020). Biochemical and cytogenetic of Imazethapyr on Cicer arietinum L. Journal of Applied Biology and Biotechnology 8(2):73-77.
Crossref

 

Huang D, Zhang X, Zhang C, Li H, Li D, Hu Y, Yang F, Qi Y (2018). 2,4-Dichlorophenol induces DNA damage through ROS accumulation and GSH depletion in goldfish Carassius auratus. Environmental and Molecular Mutagenesis 59(9):798-804.
Crossref

 

Igbinosa EO, Odjadjare EE, Chigor VN, Igbinosa IH, Emoghene AO, Ekhaise FO, Igiehon NO, Idemudia OG (2013). Toxicological Profile of Chlorophenols and their derivative in the Environment: The public health respective. The Scientific World Journal 460215.P:11.
Crossref

 

Inceer H, Ayaz S, Beyazo?lu O, ?entürk E (2003). Cytogenetic effects of copper chloride on the root tip cells of Helianthus annus L. Turkish Journal of Biology 27(1):43-46.

 

Iqbal M (2016). Vicia faba bioassay for environmental toxicity monitoring: A review. Chemosphere 144:785-802.
Crossref

 

Jensen J (1996). Chlorophenols in the terrestrial environment. Reviews of Environmental Contamination and Toxicology 146:25-51.
Crossref

 

Kumar S, Dubey DK (1998). Effects of gamma rays, EMS and DES on meiosis in Lathyrus sativus. Journal of Cytology and Genetics 33(2):139-147.

 

Kumar G, Rai P (2007). Genotoxic potential of mercury and cadmium in soyabean. Turkish Journal of Biology 31(1):13-18.

 

Kumar G, Singh V (2004). Studies in MI and M2 generations of azide induced medium-strong desynaptic mutant of pearl millets. The Nucleus 47:159-163.

 

Kumar G, Srivastava A (2015). Genotoxicity of herbicide Ingredients Glyphosate and Atrazine on root Meristem of Buckwhea (Fagopyrum. esculentum Moench). Jordan Journal of Biological Science 8(3):2221-226.
Crossref

 

Kumar S, Arya Sk, Roy BK, Singh AK (2010). The effects of 2,4-dichlorophenoxy acetic acid and isoproturon herbicides on the mitotic activity of wheat (Triticum sativum L.) root tips. Turkish Journal of Biology 34(1):55-66.
Crossref

 

Kü?ük D, Liman R (2018). Cytogenetic and genotoxic effects of 2-chlorophenol on Allium cepa L. root meristem cells. Environmental Science and Pollution Research 25(36):36117-36123.
Crossref

 

Lampi P, Vohlonen I, Tuomisto J, Heinonen OP (2000). Increase of specific symptoms after long-term use of chlorophenol polluted drinking water in a community. European Journal of Epidemiology 16(3):245-251.
Crossref

 

Lehnen JR LP, Vaughan MA, Vaughn KC (1990). Tertbutyl affects spindle microtubule organizing center. Journal of Experimental Botany 41(5):537-546.
Crossref

 

Liman R, Ci?erci ?H, Öztürk NS (2015). Determination of genotoxic effects of Imazethapyr herbicide in Allium cepa root cells by mitotic activity, chromosome aberration, and comet assay. Pesticide Biochemistry and Physiology118:38-42.
Crossref

 

Lone MI, Nazam N, Shaikh S, Ahmad W (2013). Genotoxicity of an organochlorine pesticide dichlorophene by micronucleus and chromosomal aberration assay using bone marrow cells of Rattus norvegicus. Caryologia 66(4):296-303.
Crossref

 

Ma TH, Cabera GL, Cebulska Wasilewska A, Chen R, Loarca F, Vandererg AL, Salamone MF (1994). Tradescantia stamen hair mutation bioassay. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 310(2):211-220.
Crossref

 

Mahakhode RH, Somkuwar SR (2013). Mitotic abnormalities induced by glyphosate in Pasoralea corylifolia. International Journal of Current Pharmaceutical Research 5(1):46-48.

 

Michalowics J, Duda W (2007). Phenols- Source and toxicity. Polish Journal of Environmental Studies 16(3):347-362.

 

Michalowicz J, Majsterek I (2010). Chlorophenols, chlorocatechols and chloroguaiacols induce DNA base oxidation in human lymphocytes. Toxicology.268(3):171-175.
Crossref

 

Morejohn LC, Fosket DE (1986). Tubulinsfrom plants fungi and protests; a review. In Shay J.W. (ed), cell ND Molecular biology of the Cytoskeleton. Plenum Publishing Crop, New York, pp. 257-329.
Crossref

 

Öcal A, Ero?lu HE (2012). In vitro cytogenetic effects of Hypericum heterophyllum in human peripheral blood lymphocytes. Bangladesh Journal of Pharmacology 7(1):36-41.
Crossref

 

Palchetti L, Mascn M (2008). Nuclei Acids Biosensor for Environmental Pollution Monitoring. The Analyst 133(7):846-845.
Crossref

 

Pavlica M, Papes D, Nagy B (1991). 2,4Dichlorophenoxyacetic acid causes chromatin and chromosome abnormalities in plant cells and mutation in cultured mammalian cells. Mutation Research 263(2):77-81.
Crossref

 

Sharma A, Kumar V, Thukral AK, Bhardwaj R (2017). Responses of Plants to pesticides Toxicity: An Overview. Planta Daninha 37:1-12.
Crossref

 

Sharma S, Vig AP (2012). Genotoxicity of Atrazine, Avenoxan, Diuron and Quizalofop-P-ethyl herbicides using the Allium cepa root chromosomal aberration assay. Terrestrial and Aquatic Environmental Toxicology 6(2):90-95.

 

Sheila M, Galloway (2000). Cytotoxicity and chromosome aberrations in vitro: Experience in industry and the case for an upper limit on toxicity in the aberration assay. Environmental and Molecular Mutagenesis 35(3):191-201.
Crossref

 

Sinha SP (1989). Genotoxicity of Pesticides. In Perspective in Cytol, Manna G. K. (Ed.) Genetics, New Delhi.

 

Tingting G, Jiangyuan H, Yongmei G, Xueyan ML, Chen Z, Naeem S, Dejun H (2017). The toxic effects of chlorophenols and associated mechanism in fish. Aquatic Toxicology 184:78-93.
Crossref

 

Tolbert PE, Shy CM, Allen J (1991). Micronucleus and other nuclear anomalies in buccal smears: A field test in snuff users. American Journal of Epidemiology 134(8):840-850.
Crossref